@fatima1amin.bsky.social
PhD student, Leibniz Institute for Neurobiology, Magdeburg, Germany
Drosophila | Learning & Memory | Action | Neuromodulation
Drosophila | Learning & Memory | Action | Neuromodulation
Pinned
Avoidance engages dopaminergic punishment in Drosophila https://www.biorxiv.org/content/10.1101/2025.07.07.663268v1
🚨🚨My PhD work pre-print🚨🚨
Check it out 👇👇
'Avoidance engages dopaminergic punishment in Drosophila'
It's a great collaborative enterprise and can't thank enough to my mentors and collaborators for the kindest efforts...fingers crossed 🤞🤞
Check it out 👇👇
'Avoidance engages dopaminergic punishment in Drosophila'
It's a great collaborative enterprise and can't thank enough to my mentors and collaborators for the kindest efforts...fingers crossed 🤞🤞
Reposted
Do flies feel pain?
Spooky new preprint from our lab on the cells and circuits that mediate nociceptive behaviors in adult Drosophila, led by graduate student (and newly minted PhD!) @jonesjes.bsky.social.
🪰⚡👻🎃
www.biorxiv.org/content/10.1...
Spooky new preprint from our lab on the cells and circuits that mediate nociceptive behaviors in adult Drosophila, led by graduate student (and newly minted PhD!) @jonesjes.bsky.social.
🪰⚡👻🎃
www.biorxiv.org/content/10.1...
October 29, 2025 at 6:56 PM
Do flies feel pain?
Spooky new preprint from our lab on the cells and circuits that mediate nociceptive behaviors in adult Drosophila, led by graduate student (and newly minted PhD!) @jonesjes.bsky.social.
🪰⚡👻🎃
www.biorxiv.org/content/10.1...
Spooky new preprint from our lab on the cells and circuits that mediate nociceptive behaviors in adult Drosophila, led by graduate student (and newly minted PhD!) @jonesjes.bsky.social.
🪰⚡👻🎃
www.biorxiv.org/content/10.1...
Reposted
Exciting news for #drosophila #connectomics and #neuroscience enthusiasts: the Drosophila male central nervous system connectome is now live for exploration. Find out more at the landing page hosted by our Janelia FlyEM collaborators www.janelia.org/project-team....
Male CNS Connectome
A team of researchers has unveiled the complete connectome of a male fruit fly central nervous system —a seamless map of all the neurons in the brain and nerve cord of a single male fruit fly and the ...
www.janelia.org
October 5, 2025 at 3:40 PM
Exciting news for #drosophila #connectomics and #neuroscience enthusiasts: the Drosophila male central nervous system connectome is now live for exploration. Find out more at the landing page hosted by our Janelia FlyEM collaborators www.janelia.org/project-team....
What an exciting week!!
Thanks to the Learning and Memory Conference and everyone 🙂🙂
Thanks to the Learning and Memory Conference and everyone 🙂🙂
October 2, 2025 at 9:22 PM
What an exciting week!!
Thanks to the Learning and Memory Conference and everyone 🙂🙂
Thanks to the Learning and Memory Conference and everyone 🙂🙂
Can a PhD hat 👩🎓be cooler than this one? Nope.
Thanks to my 2nd home (Gerber lab) for making this wonderful journey full of learning and memory.
I am wholeheartedly thankful to my mentors, collaborators, advisors, well wishers, LIN, colleagues, friends, my flies, and my family. Thank you 🙏
26/09/25
Thanks to my 2nd home (Gerber lab) for making this wonderful journey full of learning and memory.
I am wholeheartedly thankful to my mentors, collaborators, advisors, well wishers, LIN, colleagues, friends, my flies, and my family. Thank you 🙏
26/09/25
September 26, 2025 at 7:23 PM
Can a PhD hat 👩🎓be cooler than this one? Nope.
Thanks to my 2nd home (Gerber lab) for making this wonderful journey full of learning and memory.
I am wholeheartedly thankful to my mentors, collaborators, advisors, well wishers, LIN, colleagues, friends, my flies, and my family. Thank you 🙏
26/09/25
Thanks to my 2nd home (Gerber lab) for making this wonderful journey full of learning and memory.
I am wholeheartedly thankful to my mentors, collaborators, advisors, well wishers, LIN, colleagues, friends, my flies, and my family. Thank you 🙏
26/09/25
And here begins the 'LearnMamBo' era! Congratulations @obarnstedt.bsky.social as always!
We are super excited that our project ***LearnMamBo*** Neuronal Dynamics of Learning and Memory in the Mammillary Body gets an #ercstartinggrant @erc.europa.eu – we will dissect the associated circuits supporting episodic memory – REACH OUT if interested in joining this project!
a man wearing a hat and a suit says mambo no. 5 .
ALT: a man wearing a hat and a suit says mambo no. 5 .
media.tenor.com
September 4, 2025 at 3:27 PM
And here begins the 'LearnMamBo' era! Congratulations @obarnstedt.bsky.social as always!
Reposted
The first full central nervous system connectome dataset of an adult fly, with the most comprehensive annotation of sensory and motor neurons to date.
A heroic effort with contributions from many groups, a product of the collaborative spirit of the Drosophila neuroscience community.
A heroic effort with contributions from many groups, a product of the collaborative spirit of the Drosophila neuroscience community.
Happy Friday! The female adult fly brain-and-nerve-cord (BANC) connectome is now LIVE!
Explore the data here: codex.flywire.ai?dataset=banc
Check out the preprint here: doi.org/10.1101/2025...
Explore the data here: codex.flywire.ai?dataset=banc
Check out the preprint here: doi.org/10.1101/2025...
a man with a mustache in a blue suit says tiny celebration in front of a group of people
ALT: a man with a mustache in a blue suit says tiny celebration in front of a group of people
media.tenor.com
August 1, 2025 at 11:14 PM
The first full central nervous system connectome dataset of an adult fly, with the most comprehensive annotation of sensory and motor neurons to date.
A heroic effort with contributions from many groups, a product of the collaborative spirit of the Drosophila neuroscience community.
A heroic effort with contributions from many groups, a product of the collaborative spirit of the Drosophila neuroscience community.
🚨🚨My PhD work pre-print🚨🚨
Check it out 👇👇
'Avoidance engages dopaminergic punishment in Drosophila'
It's a great collaborative enterprise and can't thank enough to my mentors and collaborators for the kindest efforts...fingers crossed 🤞🤞
Check it out 👇👇
'Avoidance engages dopaminergic punishment in Drosophila'
It's a great collaborative enterprise and can't thank enough to my mentors and collaborators for the kindest efforts...fingers crossed 🤞🤞
Avoidance engages dopaminergic punishment in Drosophila https://www.biorxiv.org/content/10.1101/2025.07.07.663268v1
July 10, 2025 at 5:41 PM
🚨🚨My PhD work pre-print🚨🚨
Check it out 👇👇
'Avoidance engages dopaminergic punishment in Drosophila'
It's a great collaborative enterprise and can't thank enough to my mentors and collaborators for the kindest efforts...fingers crossed 🤞🤞
Check it out 👇👇
'Avoidance engages dopaminergic punishment in Drosophila'
It's a great collaborative enterprise and can't thank enough to my mentors and collaborators for the kindest efforts...fingers crossed 🤞🤞
Reposted
Our new paper out now in Science explores how neural activity in the lateral entorhinal cortex (LEC) *drifts* over time - and *jumps* at key boundaries - to help organize events in memory.
🔗 www.science.org/doi/10.1126/...
Here's a quick summary of what we found 🧵👇
🔗 www.science.org/doi/10.1126/...
Here's a quick summary of what we found 🧵👇
June 26, 2025 at 6:15 PM
Our new paper out now in Science explores how neural activity in the lateral entorhinal cortex (LEC) *drifts* over time - and *jumps* at key boundaries - to help organize events in memory.
🔗 www.science.org/doi/10.1126/...
Here's a quick summary of what we found 🧵👇
🔗 www.science.org/doi/10.1126/...
Here's a quick summary of what we found 🧵👇
Reposted
How do brain circuits evolve? We started looking for some answers by using synapse-resolution cross-species comparative connectomics on an entire olfactory circuit 👇
bit.ly/44aVm9E
bit.ly/44aVm9E
June 12, 2025 at 11:04 AM
How do brain circuits evolve? We started looking for some answers by using synapse-resolution cross-species comparative connectomics on an entire olfactory circuit 👇
bit.ly/44aVm9E
bit.ly/44aVm9E
Reposted
Excited to share our Science paper on HaloDA1.0-the first genetically encoded far-red dopamine sensor! 🥳It enables powerful multiplex imaging in neurons, brain slices, and live animals.🧠🔬 #GRABsensors #Dopamine www.science.org/doi/10.1126/...
In vivo multiplex imaging of dynamic neurochemical networks with designed far-red dopamine sensors
Dopamine (DA) plays a crucial role in a variety of brain functions through intricate interactions with other neuromodulators and intracellular signaling pathways. However, studying these complex netwo...
www.science.org
June 6, 2025 at 5:20 AM
Excited to share our Science paper on HaloDA1.0-the first genetically encoded far-red dopamine sensor! 🥳It enables powerful multiplex imaging in neurons, brain slices, and live animals.🧠🔬 #GRABsensors #Dopamine www.science.org/doi/10.1126/...
Reposted
Nature research paper: Molecular gradients shape synaptic specificity of a visuomotor transformation
https://go.nature.com/4jFNOQR
https://go.nature.com/4jFNOQR
Molecular gradients shape synaptic specificity of a visuomotor transformation - Nature
Gradients of cell recognition molecules wire a sensorimotor interface in Drosophila.
go.nature.com
June 4, 2025 at 6:40 PM
Nature research paper: Molecular gradients shape synaptic specificity of a visuomotor transformation
https://go.nature.com/4jFNOQR
https://go.nature.com/4jFNOQR
Reposted
new preprint, led by @ellenlesser.bsky.social, on proprioceptive sensing of the Drosophila wing. tldr, there are a lot of proprioceptors out in the wing and they are wildly diverse and complex (eg, compared to the fly leg). just one example in this image...(1/4)
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
June 3, 2025 at 2:01 PM
new preprint, led by @ellenlesser.bsky.social, on proprioceptive sensing of the Drosophila wing. tldr, there are a lot of proprioceptors out in the wing and they are wildly diverse and complex (eg, compared to the fly leg). just one example in this image...(1/4)
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted
A projection from the lateral hypothalamus (LHA) to the pedunculopontine nucleus (PPN) prioritizes survival over other needs by triggering safety-directed movement
@nkrauth.bsky.social @giachiblue.bsky.social @clemmensenc.bsky.social @olekiehn.bsky.social
www.nature.com/articles/s41...
@nkrauth.bsky.social @giachiblue.bsky.social @clemmensenc.bsky.social @olekiehn.bsky.social
www.nature.com/articles/s41...
A hypothalamus–brainstem circuit governs the prioritization of safety over essential needs - Nature Neuroscience
Animals need to adapt behavior to balance survival with fulfillment of essential needs. Krauth et al. identify neurons in the lateral hypothalamus that, when activated, prioritize survival over other ...
www.nature.com
June 2, 2025 at 4:46 PM
A projection from the lateral hypothalamus (LHA) to the pedunculopontine nucleus (PPN) prioritizes survival over other needs by triggering safety-directed movement
@nkrauth.bsky.social @giachiblue.bsky.social @clemmensenc.bsky.social @olekiehn.bsky.social
www.nature.com/articles/s41...
@nkrauth.bsky.social @giachiblue.bsky.social @clemmensenc.bsky.social @olekiehn.bsky.social
www.nature.com/articles/s41...
Reposted
It is out! Read how you achieve 1.7 mm deep 3-photon imaging in prefrontal cortex with dendritic spine resolution over a week.
www.nature.com/articles/s42...
www.nature.com/articles/s42...
Three-photon in vivo imaging of neurons and glia in the medial prefrontal cortex with sub-cellular resolution - Communications Biology
Three-photon in vivo imaging provides access to medial prefrontal cortex, hippocampus and spinal cord in mice at up to 1.7 mm depth of neurons, dendrites, spines, astrocytes and microglia.
www.nature.com
June 1, 2025 at 9:58 AM
It is out! Read how you achieve 1.7 mm deep 3-photon imaging in prefrontal cortex with dendritic spine resolution over a week.
www.nature.com/articles/s42...
www.nature.com/articles/s42...
Reposted
Congratulations to our Human Neural Circuitry team; bit.ly/4dEyX7Z publishes today in Science! This was the hardest challenge of my career, but one of the most rewarding, after years of rebuilding– & expanding my inpatient neuropsychiatry in the service of basic discovery bsky.app/profile/deis...
May 30, 2025 at 5:32 AM
Congratulations to our Human Neural Circuitry team; bit.ly/4dEyX7Z publishes today in Science! This was the hardest challenge of my career, but one of the most rewarding, after years of rebuilding– & expanding my inpatient neuropsychiatry in the service of basic discovery bsky.app/profile/deis...
Reposted
New preprint from the lab, led by grad student Brandon Pratt, on the encoding properties and sensorimotor function of proprioceptive limit detectors (ie, hair plates) in the fly leg.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
May 19, 2025 at 1:44 PM
New preprint from the lab, led by grad student Brandon Pratt, on the encoding properties and sensorimotor function of proprioceptive limit detectors (ie, hair plates) in the fly leg.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted
Nature research paper: Dopaminergic action prediction errors serve as a value-free teaching signal
https://go.nature.com/4kjOtIi
https://go.nature.com/4kjOtIi
Dopaminergic action prediction errors serve as a value-free teaching signal - Nature
Dopaminergic action prediction error signals are used by mice as a value-free teaching signal to reinforce stable sound–action associations in the tail of the striatum.
go.nature.com
May 15, 2025 at 12:10 PM
Nature research paper: Dopaminergic action prediction errors serve as a value-free teaching signal
https://go.nature.com/4kjOtIi
https://go.nature.com/4kjOtIi
Reposted
Happy to announce that our paper examining the function of leg mechanosensory neurons by way of their connectivity is finally officially published! rdcu.be/ekqVt
Divergent neural circuits for proprioceptive and exteroceptive sensing of the Drosophila leg
Nature Communications - Determining whether somatosensory neurons are involved in internal or external sensing remains a challenge. Here, the authors show that analyzing connectivity is a powerful...
rdcu.be
May 2, 2025 at 2:19 PM
Happy to announce that our paper examining the function of leg mechanosensory neurons by way of their connectivity is finally officially published! rdcu.be/ekqVt
Reposted
A competitive disinhibitory network for robust optic flow processing in Drosophila
#Drosophila
#Drosophila
A competitive disinhibitory network for robust optic flow processing in Drosophila
#Drosophila
PubMed link
pubmed.ncbi.nlm.nih.gov
May 2, 2025 at 5:23 AM
A competitive disinhibitory network for robust optic flow processing in Drosophila
#Drosophila
#Drosophila
Reposted
How does a fly’s nervous system differ by sex? 🧠🪰
Led by Tomke Stürner & Paul Brooks, Greg Jefferis’ group, the Drosophila Connectomics group (University of Cambridge) & global colleagues publish a new atlas, revealing sex-specific neurons driving distinct behaviours.
www.nature.com/articles/s41...
Led by Tomke Stürner & Paul Brooks, Greg Jefferis’ group, the Drosophila Connectomics group (University of Cambridge) & global colleagues publish a new atlas, revealing sex-specific neurons driving distinct behaviours.
www.nature.com/articles/s41...
April 30, 2025 at 3:19 PM
How does a fly’s nervous system differ by sex? 🧠🪰
Led by Tomke Stürner & Paul Brooks, Greg Jefferis’ group, the Drosophila Connectomics group (University of Cambridge) & global colleagues publish a new atlas, revealing sex-specific neurons driving distinct behaviours.
www.nature.com/articles/s41...
Led by Tomke Stürner & Paul Brooks, Greg Jefferis’ group, the Drosophila Connectomics group (University of Cambridge) & global colleagues publish a new atlas, revealing sex-specific neurons driving distinct behaviours.
www.nature.com/articles/s41...
Reposted
Many animals use "adaptive control" to pursue moving objects, relying on flexible feedback loops to adjust their movement gain over time. But how do neural circuits actually implement this?
Here, we show how adaptive control in Drosophila pursuit involves two specialized parallel feedback loops.
Here, we show how adaptive control in Drosophila pursuit involves two specialized parallel feedback loops.
Specialized parallel pathways for adaptive control of visual object pursuit
To pursue an unpredictably moving visual object, the brain must generate motor commands that continuously steer the object to the midline of the visual field via feedback. Behavior implies that visual...
doi.org
April 28, 2025 at 3:19 PM
Many animals use "adaptive control" to pursue moving objects, relying on flexible feedback loops to adjust their movement gain over time. But how do neural circuits actually implement this?
Here, we show how adaptive control in Drosophila pursuit involves two specialized parallel feedback loops.
Here, we show how adaptive control in Drosophila pursuit involves two specialized parallel feedback loops.
Reposted
Greater mouse-tailed bats crawl backwards over cave walls, and it seems they use their long tails to help feel their way.
Bats that walk backwards have developed unusual navigation strategy
Greater mouse-tailed bats crawl backwards over cave walls, and it seems they use their long tails to help feel their way
www.newscientist.com
April 26, 2025 at 7:36 AM
Greater mouse-tailed bats crawl backwards over cave walls, and it seems they use their long tails to help feel their way.
Reposted
Pleased to share the final published version of @glopez.bsky.social's work in @currentbiology.bsky.social! www.sciencedirect.com/science/arti...
"Region-specific nucleus accumbens dopamine signals encode distinct aspects of avoidance learning"
Congrats, Gaby!!!
"Region-specific nucleus accumbens dopamine signals encode distinct aspects of avoidance learning"
Congrats, Gaby!!!
Region-specific nucleus accumbens dopamine signals encode distinct aspects of avoidance learning
Avoidance learning—learning to avoid bad outcomes—is an essential survival behavior. Dopamine signals are widely observed in response to aversive stim…
www.sciencedirect.com
April 22, 2025 at 4:17 PM
Pleased to share the final published version of @glopez.bsky.social's work in @currentbiology.bsky.social! www.sciencedirect.com/science/arti...
"Region-specific nucleus accumbens dopamine signals encode distinct aspects of avoidance learning"
Congrats, Gaby!!!
"Region-specific nucleus accumbens dopamine signals encode distinct aspects of avoidance learning"
Congrats, Gaby!!!
Reposted
Fly journal is now on BlueSky! The world’s only academic journal dedicated to research on Drosophila & cognate insects. A fully open-access journal that combines rapid publication with high standards of peer-review. For further info and how to submit your work, see the link.
Fly
Open access research on Drosophila developmental/evolutionary biology, organogenesis, neurobiology, circadian rhythms, learning & memory, sex determination
www.tandfonline.com
April 17, 2025 at 9:39 AM
Fly journal is now on BlueSky! The world’s only academic journal dedicated to research on Drosophila & cognate insects. A fully open-access journal that combines rapid publication with high standards of peer-review. For further info and how to submit your work, see the link.
Reposted
Why do some neurons say “sleep” while others shout “stay awake!” — inside the same brain?
In fruit flies, researchers just mapped the molecular chaos behind this nightly tug-of-war. And it’s wilder than we thought.
buff.ly/nA9M8EM
In fruit flies, researchers just mapped the molecular chaos behind this nightly tug-of-war. And it’s wilder than we thought.
buff.ly/nA9M8EM
April 18, 2025 at 1:59 PM
Why do some neurons say “sleep” while others shout “stay awake!” — inside the same brain?
In fruit flies, researchers just mapped the molecular chaos behind this nightly tug-of-war. And it’s wilder than we thought.
buff.ly/nA9M8EM
In fruit flies, researchers just mapped the molecular chaos behind this nightly tug-of-war. And it’s wilder than we thought.
buff.ly/nA9M8EM