Our work on developing a fluorescent probe to measure granzyme B activity in anti-tumor immunity is finally out! pubs.acs.org/doi/10.1021/...
Granzyme B-Targeting Quenched Activity-Based Probes for Assessing Tumor Response to Immunotherapy
Molecular imaging of immune activation holds tremendous potential for the development of novel immunotherapies. In particular, chemical probes capable of detecting immune responses before changes in t...
pubs.acs.org
October 8, 2025 at 11:44 PM
Our work on developing a fluorescent probe to measure granzyme B activity in anti-tumor immunity is finally out! pubs.acs.org/doi/10.1021/...
Happy to share our work published www.nature.com/articles/s41.... We describe the design of activity-based probes and chemoproteomic strategies to study USP18.
Chemical tools to define and manipulate interferon-inducible Ubl protease USP18 - Nature Communications
USP18 is a multifunctional cysteine protease involved in IFN pathways. Here, the authors report chemical probes and chemoproteomics platforms that allow to detect and perturb USP18 activity in complex...
www.nature.com
January 22, 2025 at 11:03 PM
Happy to share our work published www.nature.com/articles/s41.... We describe the design of activity-based probes and chemoproteomic strategies to study USP18.
It was great to host @christhechang.bsky.social to CBL, NCI-Frederick. A wonderful seminar, a stimulating day full of new ideas! Thanks for the visit!
November 22, 2024 at 1:55 AM
It was great to host @christhechang.bsky.social to CBL, NCI-Frederick. A wonderful seminar, a stimulating day full of new ideas! Thanks for the visit!