Darin Takemoto
@dtake01.bsky.social
Weeder of woods. Interests: statistics, bioinformatics, music, games.
Reposted by Darin Takemoto
![Comic. Someone is claiming to predict the exact date of a future earthquake. Should you listen? [flowchart: start] → NO (There are big earthquakes constantly, so if anyone ever *does* figure this out, it will be immediately obvious that their method works and then the world’s seismologists will not shut up about it. You won’t need this flowchart.)](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:cz73r7iyiqn26upot4jtjdhk/bafkreic7wdqg4w6qfevbqzzq4esd6237pojsnpwsrbb7gaxsxobqaiwazm@jpeg)
November 10, 2025 at 8:55 PM
Reposted by Darin Takemoto
Reposted by Darin Takemoto
Delusional thinking about healthspan and longevity, now from China
"In 5 to 10 years nobody will get cancer."
"Living to 150 is definitely realistic. In a few years this will be the reality."
www.nytimes.com/2025/11/08/w...
"In 5 to 10 years nobody will get cancer."
"Living to 150 is definitely realistic. In a few years this will be the reality."
www.nytimes.com/2025/11/08/w...
In China, the Dream of Outrunning Time
www.nytimes.com
November 9, 2025 at 3:39 PM
Delusional thinking about healthspan and longevity, now from China
"In 5 to 10 years nobody will get cancer."
"Living to 150 is definitely realistic. In a few years this will be the reality."
www.nytimes.com/2025/11/08/w...
"In 5 to 10 years nobody will get cancer."
"Living to 150 is definitely realistic. In a few years this will be the reality."
www.nytimes.com/2025/11/08/w...
Reposted by Darin Takemoto
I wrote a review of James Watson's obituary by CSHL: liorpachter.wordpress.com/2025/11/08/r...
Review of Cold Spring Harbor Laboratory’s Obituary for Dr. James Watson
James Watson, who described himself as “not a racist in a conventional way”, has died at the age of 97. Below is a review of an obituary for Dr. James Watson published by Cold Spring Ha…
liorpachter.wordpress.com
November 8, 2025 at 9:58 PM
I wrote a review of James Watson's obituary by CSHL: liorpachter.wordpress.com/2025/11/08/r...
Reposted by Darin Takemoto
In an interim analysis, sibeprenlimab, a humanized IgG2 monoclonal antibody that inhibits the proliferation-inducing ligand APRIL (a key driver of IgA nephropathy), reduced proteinuria as compared with placebo. nej.md/493Xtza
@asnkidney.bsky.social | #KidneyWk
@asnkidney.bsky.social | #KidneyWk
November 8, 2025 at 4:35 PM
In an interim analysis, sibeprenlimab, a humanized IgG2 monoclonal antibody that inhibits the proliferation-inducing ligand APRIL (a key driver of IgA nephropathy), reduced proteinuria as compared with placebo. nej.md/493Xtza
@asnkidney.bsky.social | #KidneyWk
@asnkidney.bsky.social | #KidneyWk
Reposted by Darin Takemoto
Reposted by Darin Takemoto
In case anyone is wondering if Watson was really THAT bad, @lpachter.bsky.social compiled a list of quotes that are absolutely not for the faint of heart.
liorpachter.wordpress.com/2018/05/18/j...
liorpachter.wordpress.com/2018/05/18/j...
November 7, 2025 at 10:18 PM
In case anyone is wondering if Watson was really THAT bad, @lpachter.bsky.social compiled a list of quotes that are absolutely not for the faint of heart.
liorpachter.wordpress.com/2018/05/18/j...
liorpachter.wordpress.com/2018/05/18/j...
Reposted by Darin Takemoto
A Snowy Egret & Tricolored Heron for #BirdOfTheDay. It may look like a dance in the 1st photo but they are #fighting Started by the Snowy Egret dive bombing the heron as it stalked the mud flat during low tide and continued as an aerial battle into a nearby neighborhood. photos first 😉🪶 #birds
November 7, 2025 at 2:49 PM
A Snowy Egret & Tricolored Heron for #BirdOfTheDay. It may look like a dance in the 1st photo but they are #fighting Started by the Snowy Egret dive bombing the heron as it stalked the mud flat during low tide and continued as an aerial battle into a nearby neighborhood. photos first 😉🪶 #birds
Reposted by Darin Takemoto
Contrast this with the response of a president who was an actual decent human being.
November 6, 2025 at 5:51 PM
Contrast this with the response of a president who was an actual decent human being.
Reposted by Darin Takemoto
holy shit -- one of Trump's toadies just passed out and the White House event is brought to an abrupt end
November 6, 2025 at 5:38 PM
holy shit -- one of Trump's toadies just passed out and the White House event is brought to an abrupt end
A nice set of guidelines to make biomedical data resources (or any data resources) accessible
doi.org/qcv7
doi.org/qcv7
Ten simple rules for making biomedical data resources accessible
doi.org
November 7, 2025 at 1:54 PM
A nice set of guidelines to make biomedical data resources (or any data resources) accessible
doi.org/qcv7
doi.org/qcv7
Reposted by Darin Takemoto
Majestic Egret At The Wetlands by Debra Martz
Reddish Egret captured in Port Aransas, Texas.
debra-martz.pixels.com/featured/maj...
#ReddishEgret #egret ##bird #giftideas #birds #aves #avian #BirdLovers #featheredFriends #ornithology #photography #PhotographyIsArt #BuyIntoArt #AYearForArt
Reddish Egret captured in Port Aransas, Texas.
debra-martz.pixels.com/featured/maj...
#ReddishEgret #egret ##bird #giftideas #birds #aves #avian #BirdLovers #featheredFriends #ornithology #photography #PhotographyIsArt #BuyIntoArt #AYearForArt
November 4, 2025 at 1:14 PM
Majestic Egret At The Wetlands by Debra Martz
Reddish Egret captured in Port Aransas, Texas.
debra-martz.pixels.com/featured/maj...
#ReddishEgret #egret ##bird #giftideas #birds #aves #avian #BirdLovers #featheredFriends #ornithology #photography #PhotographyIsArt #BuyIntoArt #AYearForArt
Reddish Egret captured in Port Aransas, Texas.
debra-martz.pixels.com/featured/maj...
#ReddishEgret #egret ##bird #giftideas #birds #aves #avian #BirdLovers #featheredFriends #ornithology #photography #PhotographyIsArt #BuyIntoArt #AYearForArt
Reposted by Darin Takemoto
Analysis of ancient genomes shows Denisovan ancestry in Eurasia varied over 40,000 years, with early East Asians carrying the highest levels and later gene flow shaping regional differences. doi.org/g9856x
Dynamics of Denisovan ancestry in Eurasians over the past 40,000 years revealed
Modern humans inherited part of their ancestry from multiple, genetically distinct Denisovan groups through interbreeding events.
phys.org
November 4, 2025 at 4:05 PM
Analysis of ancient genomes shows Denisovan ancestry in Eurasia varied over 40,000 years, with early East Asians carrying the highest levels and later gene flow shaping regional differences. doi.org/g9856x
Reposted by Darin Takemoto
This week's @nature.com cover highlights a report of A.I.- mediated distortion
When #ChatGPT was asked to rate 40,000 résumés, it ranked the older male candidates as better quality than the younger female applicants nature.com/articles/s41...
When #ChatGPT was asked to rate 40,000 résumés, it ranked the older male candidates as better quality than the younger female applicants nature.com/articles/s41...
November 2, 2025 at 6:12 PM
This week's @nature.com cover highlights a report of A.I.- mediated distortion
When #ChatGPT was asked to rate 40,000 résumés, it ranked the older male candidates as better quality than the younger female applicants nature.com/articles/s41...
When #ChatGPT was asked to rate 40,000 résumés, it ranked the older male candidates as better quality than the younger female applicants nature.com/articles/s41...
Reposted by Darin Takemoto
A word that has become a euphemism for promoting and selling things without data or evidence
November 2, 2025 at 6:19 PM
A word that has become a euphemism for promoting and selling things without data or evidence
Reposted by Darin Takemoto
🤝 I’m forming a focus group to synergize and supercharge evidence‑based science communication on social media. Want to join? Drop a comment below or DM me. #SciComm
November 1, 2025 at 11:50 AM
🤝 I’m forming a focus group to synergize and supercharge evidence‑based science communication on social media. Want to join? Drop a comment below or DM me. #SciComm
Reposted by Darin Takemoto
Bottom line of systematic assessment of studies on Covid vaccinations/boosters:
~50% reduction of hospitalization, across all adults (not just older) who are not immunocompromised
Real data on vaccine-induced myocarditis: occurred in 1-3 per 100,000 male adolescents
www.nejm.org/doi/full/10....
~50% reduction of hospitalization, across all adults (not just older) who are not immunocompromised
Real data on vaccine-induced myocarditis: occurred in 1-3 per 100,000 male adolescents
www.nejm.org/doi/full/10....
October 31, 2025 at 8:17 PM
Bottom line of systematic assessment of studies on Covid vaccinations/boosters:
~50% reduction of hospitalization, across all adults (not just older) who are not immunocompromised
Real data on vaccine-induced myocarditis: occurred in 1-3 per 100,000 male adolescents
www.nejm.org/doi/full/10....
~50% reduction of hospitalization, across all adults (not just older) who are not immunocompromised
Real data on vaccine-induced myocarditis: occurred in 1-3 per 100,000 male adolescents
www.nejm.org/doi/full/10....
Reposted by Darin Takemoto
Rufus Wainwright changes lyrics in ‘O Canada’ as rebuke to Trump’s 51st state comments
Rufus Wainwright changes lyrics in ‘O Canada’ as rebuke to Trump’s 51st state comments
Rufus Wainwright gave O Canada a subtle twist before Game 5 of the World Series on Wednesday night at Dodger Stadium.
www.ctvnews.ca
October 30, 2025 at 4:03 AM
Rufus Wainwright changes lyrics in ‘O Canada’ as rebuke to Trump’s 51st state comments
Reposted by Darin Takemoto
On the nominee..."as they seek to dismantle the system that awarded them" www.nytimes.com/2025/10/30/o...
Opinion | The Doctor Who Hates Medicine
www.nytimes.com
October 30, 2025 at 1:47 PM
On the nominee..."as they seek to dismantle the system that awarded them" www.nytimes.com/2025/10/30/o...
Reposted by Darin Takemoto
![Comic. Two-column table. Column A lists planets: Mercury, Venus, Earth, Mars, Jupiter, Saturn, Uranus, Neptune. Column B has checkmark boxes for whether the planets have rings: the outer planets’ boxes are checked, and Earth has a red check. [Earth with a ring with an array pf points around it. An arrow labeled “Geostationary Satellite Bel”t points to the ring.] [caption] Astronomy fact: A century ago, Earth didn’t have rings, but we have one now! It’s where all the satellite dishes are pointed.](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:cz73r7iyiqn26upot4jtjdhk/bafkreifauh76r3os5nnzjvkcz5sl2pgx5iz4sgkxebqjw3aogjn6e677aa@jpeg)
October 20, 2025 at 10:44 PM
Reposted by Darin Takemoto
MSNBC captured the crowd from the Boston "No Kings" rally:
October 18, 2025 at 6:49 PM
MSNBC captured the crowd from the Boston "No Kings" rally:
Reposted by Darin Takemoto
Strategically charging and discharging electric vehicles to the grid can reduce overall emissions, improve public health, and lower energy costs while supporting renewable energy expansion. doi.org/g9643g
Letting EVs take a load off the grid could result in 'negative emissions' while saving drivers money
Letting electric vehicles strategically charge from and discharge to the grid could spark environmental and public health benefits for Americans, according to a new study from the University of Michigan and Carnegie Mellon University.
techxplore.com
October 16, 2025 at 3:40 PM
Strategically charging and discharging electric vehicles to the grid can reduce overall emissions, improve public health, and lower energy costs while supporting renewable energy expansion. doi.org/g9643g
Reposted by Darin Takemoto
Gene therapy has restored and maintained immune function in most children with ADA-SCID, with stable results and a strong safety profile observed over long-term follow-up.
Gene therapy delivers lasting immune protection in children with rare disorder
An experimental gene therapy developed by researchers at UCLA, University College London and Great Ormond Street Hospital has restored and maintained immune system function in 59 of 62 children born with ADA-SCID, a rare and deadly genetic immune disorder.
medicalxpress.com
October 15, 2025 at 9:00 PM
Gene therapy has restored and maintained immune function in most children with ADA-SCID, with stable results and a strong safety profile observed over long-term follow-up.
Reposted by Darin Takemoto
Analysis adjusting for common biases suggests that happiness does not follow a U-shaped curve with age, but instead gradually declines through adulthood with a sharper drop in later years.
By removing common biases, study debunks U-shaped happiness curve with age
Many survey-based studies have been conducted to try to understand how happiness changes over a person's lifetime. While there have been a few different outcomes, the most common has been the U-shaped curve.
phys.org
October 10, 2025 at 4:02 PM
Analysis adjusting for common biases suggests that happiness does not follow a U-shaped curve with age, but instead gradually declines through adulthood with a sharper drop in later years.