di Bernardo Lab
@diegodibi.bsky.social
#Syntheticbiology to advance gene and cell therapy in rare genetic disease is our major focus. We rely on biomedical engineering, molecular biology and bioinformatics to achieve this goal. https://dibernardo.tigem.it
Reposted by di Bernardo Lab
Are GLP-1s the first longevity drugs? go.nature.com/49aN7gR
November 12, 2025 at 8:42 PM
Are GLP-1s the first longevity drugs? go.nature.com/49aN7gR
Reposted by di Bernardo Lab
Our 2nd online talk of the AI Hub in Generative Models generative biology meetings is on November 20th at 12pm UK time. We have @alextong.bsky.social presenting "Scalable Equilibrium Sampling via Generative Modelling" hosted by @jhartford.bsky.social - register here lnkd.in/eQUhfZjV
LinkedIn
This link will take you to a page that’s not on LinkedIn
lnkd.in
November 12, 2025 at 8:43 AM
Our 2nd online talk of the AI Hub in Generative Models generative biology meetings is on November 20th at 12pm UK time. We have @alextong.bsky.social presenting "Scalable Equilibrium Sampling via Generative Modelling" hosted by @jhartford.bsky.social - register here lnkd.in/eQUhfZjV
Reposted by di Bernardo Lab
Work published today in @natbiotech.nature.com from Arc’s Luke Gilbert and Patrick Hsu labs presents a new way to insert large DNA sequences into the genome using engineered recombinases that don’t require DNA cutting or rely on the cell's repair machinery.
November 6, 2025 at 5:46 PM
Work published today in @natbiotech.nature.com from Arc’s Luke Gilbert and Patrick Hsu labs presents a new way to insert large DNA sequences into the genome using engineered recombinases that don’t require DNA cutting or rely on the cell's repair machinery.
Reposted by di Bernardo Lab
Meet our speakers for #SynBio26 🌟
Field experts will provide fascinating insights on how synthetic based-biology innovations are transforming human health and planetary sustainability.
Submit an abstract by 1 December 2025 - bursaries available
📎 bit.ly/43nlbBW
#ALife ⚙️🧫
Field experts will provide fascinating insights on how synthetic based-biology innovations are transforming human health and planetary sustainability.
Submit an abstract by 1 December 2025 - bursaries available
📎 bit.ly/43nlbBW
#ALife ⚙️🧫
October 15, 2025 at 10:00 AM
Meet our speakers for #SynBio26 🌟
Field experts will provide fascinating insights on how synthetic based-biology innovations are transforming human health and planetary sustainability.
Submit an abstract by 1 December 2025 - bursaries available
📎 bit.ly/43nlbBW
#ALife ⚙️🧫
Field experts will provide fascinating insights on how synthetic based-biology innovations are transforming human health and planetary sustainability.
Submit an abstract by 1 December 2025 - bursaries available
📎 bit.ly/43nlbBW
#ALife ⚙️🧫
dibernardo.tigem.it/join-us Postdoctoral Positions in Synthetic Biology – Join the DIMERCIRCUITS Project funded by an ERC Advanced Grant starting in 2026.
di Bernardo Lab - Join Us
Postdoctoral Positions in Synthetic Biology – Join the DIMERCIRCUITS Project funded by an ERC Advanced Grant starting in 2026.
My lab is looking for highly motivated postdoctoral researchers to join o...
dibernardo.tigem.it
October 24, 2025 at 7:46 AM
dibernardo.tigem.it/join-us Postdoctoral Positions in Synthetic Biology – Join the DIMERCIRCUITS Project funded by an ERC Advanced Grant starting in 2026.
New from our lab!!! thanks to a fantastic graduate student (Adele De Hoeffer) a small blog on how to use #AI language models to write DNA thanks to @hf.co
huggingface.co/blog/hugging...
huggingface.co/blog/hugging...
Promoter-GPT: Writing DNA Instructions with Language Models
A Blog post by Hugging Science on Hugging Face
huggingface.co
October 22, 2025 at 3:15 PM
New from our lab!!! thanks to a fantastic graduate student (Adele De Hoeffer) a small blog on how to use #AI language models to write DNA thanks to @hf.co
huggingface.co/blog/hugging...
huggingface.co/blog/hugging...
Reposted by di Bernardo Lab
Research reveals that the daily #yogurt consumption of the world’s oldest woman is linked to her much younger #cell #age.
From a team including Maria A. Blasco at @cniostopcancer.bsky.social.
🇪🇺 #FrontierResearch @scienceinnovation.ec.europa.eu #cancer @manuelansede.bsky.social 🧪
From a team including Maria A. Blasco at @cniostopcancer.bsky.social.
🇪🇺 #FrontierResearch @scienceinnovation.ec.europa.eu #cancer @manuelansede.bsky.social 🧪
She Lived To 117. Here’s How The World’s Oldest Woman’s Cells Stayed Decades Younger Than Her Age - NewsBreak
Study suggests Maria Branyas Morera’s daily yogurt habit could have shaped her tremendously healthy gut microbiome In A Nutshell Maria Branyas Morera lived
buff.ly
October 19, 2025 at 11:30 AM
Research reveals that the daily #yogurt consumption of the world’s oldest woman is linked to her much younger #cell #age.
From a team including Maria A. Blasco at @cniostopcancer.bsky.social.
🇪🇺 #FrontierResearch @scienceinnovation.ec.europa.eu #cancer @manuelansede.bsky.social 🧪
From a team including Maria A. Blasco at @cniostopcancer.bsky.social.
🇪🇺 #FrontierResearch @scienceinnovation.ec.europa.eu #cancer @manuelansede.bsky.social 🧪
Reposted by di Bernardo Lab
Arc is looking for an outstanding early-career scientist to be our next Science Fellow. This program provides resources and freedom for those looking to transition into a principal investigator role immediately after doctoral training. Apply here: arcinstitute.org/programs/sea...
October 13, 2025 at 7:36 PM
Arc is looking for an outstanding early-career scientist to be our next Science Fellow. This program provides resources and freedom for those looking to transition into a principal investigator role immediately after doctoral training. Apply here: arcinstitute.org/programs/sea...
Reposted by di Bernardo Lab
I'm very excited to announce that UNC Biology has 6 faculty positions open this year! The first is for an Asst Professor who studies organismal resilience using an integrative approach 1/n
unc.peopleadmin.com/postings/307...
unc.peopleadmin.com/postings/307...
October 12, 2025 at 2:20 PM
I'm very excited to announce that UNC Biology has 6 faculty positions open this year! The first is for an Asst Professor who studies organismal resilience using an integrative approach 1/n
unc.peopleadmin.com/postings/307...
unc.peopleadmin.com/postings/307...
Just back from the ESCGT 2025 in Sevilla Spain with my fantastic post docs who presented their work on engineering AAV producer cell lines and novel ways to address gene dosage compensation in gene replacement therapy, all using #syntheticbiology
October 13, 2025 at 7:32 AM
Just back from the ESCGT 2025 in Sevilla Spain with my fantastic post docs who presented their work on engineering AAV producer cell lines and novel ways to address gene dosage compensation in gene replacement therapy, all using #syntheticbiology
Reposted by di Bernardo Lab
The team is already working to expand the platform’s abilities, including testing in clinically relevant immune and stem cells, and engineering future versions of the system that can rearrange sequences beyond one megabase.
Learn more in the full paper: www.science.org/doi/10.1126/...
Learn more in the full paper: www.science.org/doi/10.1126/...
Megabase-scale human genome rearrangement with programmable bridge recombinases
Bridge recombinases are naturally occurring RNA-guided DNA recombinases that we previously demonstrated can programmably insert, excise, and invert DNA in vitro and in Escherichia coli. In this study,...
www.science.org
September 25, 2025 at 6:27 PM
The team is already working to expand the platform’s abilities, including testing in clinically relevant immune and stem cells, and engineering future versions of the system that can rearrange sequences beyond one megabase.
Learn more in the full paper: www.science.org/doi/10.1126/...
Learn more in the full paper: www.science.org/doi/10.1126/...
Reposted by di Bernardo Lab
🧪Roman Jerala @kemijski.bsky.social developed a new method for modular protein design that allows controlled assembly and disassembly.
The work is publicly available and could support advances in synthetic biology.
👉 europa.eu/!4GrrNf
#Biochemistry #Catalysis #GeneEditing @addgene.bsky.social
The work is publicly available and could support advances in synthetic biology.
👉 europa.eu/!4GrrNf
#Biochemistry #Catalysis #GeneEditing @addgene.bsky.social
September 22, 2025 at 6:56 AM
🧪Roman Jerala @kemijski.bsky.social developed a new method for modular protein design that allows controlled assembly and disassembly.
The work is publicly available and could support advances in synthetic biology.
👉 europa.eu/!4GrrNf
#Biochemistry #Catalysis #GeneEditing @addgene.bsky.social
The work is publicly available and could support advances in synthetic biology.
👉 europa.eu/!4GrrNf
#Biochemistry #Catalysis #GeneEditing @addgene.bsky.social
Reposted by di Bernardo Lab
Please repost!
Postdoc in adaptive laboratory evolution and C1 synthetic metabolism!
Location: DTU Biosustain
🦠🧬🔬
Starting in 01/2026!
Fell free to reach out if you have questions!
efzu.fa.em2.oraclecloud.com/hcmUI/Candid...
Postdoc in adaptive laboratory evolution and C1 synthetic metabolism!
Location: DTU Biosustain
🦠🧬🔬
Starting in 01/2026!
Fell free to reach out if you have questions!
efzu.fa.em2.oraclecloud.com/hcmUI/Candid...
efzu.fa.em2.oraclecloud.com
September 12, 2025 at 11:43 AM
Please repost!
Postdoc in adaptive laboratory evolution and C1 synthetic metabolism!
Location: DTU Biosustain
🦠🧬🔬
Starting in 01/2026!
Fell free to reach out if you have questions!
efzu.fa.em2.oraclecloud.com/hcmUI/Candid...
Postdoc in adaptive laboratory evolution and C1 synthetic metabolism!
Location: DTU Biosustain
🦠🧬🔬
Starting in 01/2026!
Fell free to reach out if you have questions!
efzu.fa.em2.oraclecloud.com/hcmUI/Candid...
Join our lab dibernardo.tigem.it for the #ERC-funded project DIMERCIRCUITS at @tigem.bsky.social. We are building synthetic gene circuits to power next-generation gene and cell therapies. We are looking for candidates with a PhD in #SyntheticBiology or related. Apply by email: dibernardo@tigem.it
September 10, 2025 at 10:36 AM
Join our lab dibernardo.tigem.it for the #ERC-funded project DIMERCIRCUITS at @tigem.bsky.social. We are building synthetic gene circuits to power next-generation gene and cell therapies. We are looking for candidates with a PhD in #SyntheticBiology or related. Apply by email: dibernardo@tigem.it
Reposted by di Bernardo Lab
My MCDB dept is accepting applications for a faculty position at the Assistant Professor level!
Applications Due by October 15, 2025
We welcome applications from all areas of physiology and neuroscience, spanning molecular, cellular, systems, and organismal levels.
lsa.umich.edu/mcdb/news-ev...
Applications Due by October 15, 2025
We welcome applications from all areas of physiology and neuroscience, spanning molecular, cellular, systems, and organismal levels.
lsa.umich.edu/mcdb/news-ev...
MCDB Opens Search for Faculty | U-M LSA Molecular, Cellular, and Developmental Biology (MCDB)
MCDB welcomes applications at the Assistant Professor level from outstanding biological scientists in all areas of physiology and neuroscience, spanning molecular, cellular, systems, and organismal le...
lsa.umich.edu
August 26, 2025 at 1:29 PM
My MCDB dept is accepting applications for a faculty position at the Assistant Professor level!
Applications Due by October 15, 2025
We welcome applications from all areas of physiology and neuroscience, spanning molecular, cellular, systems, and organismal levels.
lsa.umich.edu/mcdb/news-ev...
Applications Due by October 15, 2025
We welcome applications from all areas of physiology and neuroscience, spanning molecular, cellular, systems, and organismal levels.
lsa.umich.edu/mcdb/news-ev...
Reposted by di Bernardo Lab
Synthetic biology meets diagnostics: Engineering biosensing platforms for rapid and accurate pathogen and viral detection
doi.org/10.1016/j.bi...
doi.org/10.1016/j.bi...
September 7, 2025 at 3:24 PM
Synthetic biology meets diagnostics: Engineering biosensing platforms for rapid and accurate pathogen and viral detection
doi.org/10.1016/j.bi...
doi.org/10.1016/j.bi...
Reposted by di Bernardo Lab
The #MaxPlanckPostdocProgram offers a guaranteed contract of at least 3 years, targeted mentoring, and career workshops. The call for applications is open now! 🚀 Take advantage of this opportunity and browse the job vacancies. www.mpg.de/en/max-planc...
September 1, 2025 at 8:46 AM
The #MaxPlanckPostdocProgram offers a guaranteed contract of at least 3 years, targeted mentoring, and career workshops. The call for applications is open now! 🚀 Take advantage of this opportunity and browse the job vacancies. www.mpg.de/en/max-planc...
Reposted by di Bernardo Lab
Come and join us at a free complementary Japan-UK Engineering Biology meeting after the main ESSL conference (essl2025.org/). A few spaces left to some see some of the up and coming superstars of #synbio in the UK!
September 1, 2025 at 8:31 PM
Come and join us at a free complementary Japan-UK Engineering Biology meeting after the main ESSL conference (essl2025.org/). A few spaces left to some see some of the up and coming superstars of #synbio in the UK!
Reposted by di Bernardo Lab
Your DNA sequence reveals a rare mutation. Will you get the disease, i.e. penetrance? A new study using machine learning predicts this across 10 common diseases, 1,600 genomic variants
New @science.org
science.org/doi/10.1126/...
New @science.org
science.org/doi/10.1126/...
August 28, 2025 at 6:18 PM
Your DNA sequence reveals a rare mutation. Will you get the disease, i.e. penetrance? A new study using machine learning predicts this across 10 common diseases, 1,600 genomic variants
New @science.org
science.org/doi/10.1126/...
New @science.org
science.org/doi/10.1126/...
Reposted by di Bernardo Lab
A benchmarking competition improves tools that predict how regulatory regions control gene expression go.nature.com/3NnblYZ
rdcu.be/eCbmL
rdcu.be/eCbmL
A community effort to optimize sequence-based deep learning models of gene regulation - Nature Biotechnology
A benchmarking competition improves tools that predict how regulatory regions control gene expression.
go.nature.com
August 29, 2025 at 1:33 AM
A benchmarking competition improves tools that predict how regulatory regions control gene expression go.nature.com/3NnblYZ
rdcu.be/eCbmL
rdcu.be/eCbmL
Reposted by di Bernardo Lab
Strategies and applications of synthetic cell communication
doi.org/10.1038/s415...
doi.org/10.1038/s415...
Strategies and applications of synthetic cell communication - Nature Chemical Biology
Recent advances in engineering bottom-up synthetic cells have created powerful compartmentalized biochemical reactors with cell-like abilities. To push the boundaries of the collective capabilities of...
doi.org
August 29, 2025 at 9:20 AM
Strategies and applications of synthetic cell communication
doi.org/10.1038/s415...
doi.org/10.1038/s415...
Reposted by di Bernardo Lab
EMBL Cell Biology and Biophysics department is searching for a new director. A major position to lead this field in Europe and beyond.
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
Head of the Cell Biology and Biophysics Unit
The European Molecular Biology Laboratory (EMBL) is Europe’s flagship life sciences organisation, and one of the world’s leading research institutions. An intergovernmental organisation of 29 Member S...
embl.wd103.myworkdayjobs.com
July 29, 2025 at 7:50 AM
EMBL Cell Biology and Biophysics department is searching for a new director. A major position to lead this field in Europe and beyond.
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
Reposted by di Bernardo Lab
Optical pooled screening is enhanced by amplification of barcodes before in situ sequencing go.nature.com/3ZVzqOi
rdcu.be/exfh0
rdcu.be/exfh0
Multiplexed, image-based pooled screens in primary cells and tissues with PerturbView - Nature Biotechnology
Optical pooled screening is enhanced by amplification of barcodes before in situ sequencing.
go.nature.com
July 23, 2025 at 1:39 AM
Optical pooled screening is enhanced by amplification of barcodes before in situ sequencing go.nature.com/3ZVzqOi
rdcu.be/exfh0
rdcu.be/exfh0
We are hiring a Bioinformatician expert in NGS for our Bioinformatics Core @tigem.bsky.social please share with anyone that may be interested.
July 22, 2025 at 7:24 AM
We are hiring a Bioinformatician expert in NGS for our Bioinformatics Core @tigem.bsky.social please share with anyone that may be interested.
Today, I’m really happy to host Caleb Bashore from Rice University at Telethon Institute of Genetics and Medicine (TIGEM). He’s doing amazing workin synthetic biology so if you are in the Naples area and wants to attend his seminar today you’re welcome.
www.tigem.it/newsroom/sem...
www.tigem.it/newsroom/sem...
Caleb J. Bashor, PhD - "Engineering synthetic regulatory circuits in human cells"
www.tigem.it
July 15, 2025 at 6:02 AM
Today, I’m really happy to host Caleb Bashore from Rice University at Telethon Institute of Genetics and Medicine (TIGEM). He’s doing amazing workin synthetic biology so if you are in the Naples area and wants to attend his seminar today you’re welcome.
www.tigem.it/newsroom/sem...
www.tigem.it/newsroom/sem...