D Flemming Hansen
@dflemminghansen.bsky.social
Passion for dynamics, relaxation, and deep learning. Group leader @crick.ac.uk and Professor and chair of NMR spectroscopy @ucl.ac.uk
https://www.ucl.ac.uk/hansen-lab/
https://www.ucl.ac.uk/hansen-lab/
Pinned
A combined NMR and deep neural network approach for enhancing the spectral resolution of aromatic side chains in proteins
Combining developments in deep learning and NMR opens up opportunities like high-resolution aromatic spectra from protein samples.
doi.org
Tailored NMR experiments combined with a new DNN provide high-resolution spectra of aromatic side chains and accurate uncertainty estimates - enabling quantifications of dynamics and kinetics
doi.org/10.1126/scia...
#ScienceAdvances @crick.ac.uk @uclofficial.bsky.social @ukri.org
#NMRchat
doi.org/10.1126/scia...
#ScienceAdvances @crick.ac.uk @uclofficial.bsky.social @ukri.org
#NMRchat
Reposted by D Flemming Hansen
Delighted to announce @tlhr.bsky.social, @g-heller.bsky.social and I are building the UK’s first FRO @bindresearch.org with the goal of making disordered proteins druggable. Interested in doing breakthrough open science in an innovative organisation in Central London? We’d love to hear from you!
February 11, 2025 at 9:46 AM
Delighted to announce @tlhr.bsky.social, @g-heller.bsky.social and I are building the UK’s first FRO @bindresearch.org with the goal of making disordered proteins druggable. Interested in doing breakthrough open science in an innovative organisation in Central London? We’d love to hear from you!
Reposted by D Flemming Hansen
Today @gogs-k.bsky.social, @tlhr.bsky.social, and I are launching @bindresearch.org, a UK-based not-for-profit research startup to deliver publicly–available tools and datasets to make intrinsically disordered proteins druggable. 🍝 💊🧲 💻 🦠
February 11, 2025 at 9:26 AM
Today @gogs-k.bsky.social, @tlhr.bsky.social, and I are launching @bindresearch.org, a UK-based not-for-profit research startup to deliver publicly–available tools and datasets to make intrinsically disordered proteins druggable. 🍝 💊🧲 💻 🦠
Reposted by D Flemming Hansen
Breakthrough, led by D. Flemming Hansen @dflemminghansen.bsky.social @uclofficial.bsky.social and colleagues, addresses current challenges in obtaining high-resolution NMR spectra for aromatic residues www.ucl.ac.uk/lifesciences... #NMRnews #NMRchat #NMR 🧲
Combined NMR and Deep Neural Network approach enhances resolution of protein aromatic side chains
FID-Net-2, a deep learning model, enhances the resolution of 1H-13C NMR spectra for aromatic side chains. It offers detailed structural and dynamic insights that improve NMR analysis in structural bio...
www.ucl.ac.uk
January 11, 2025 at 6:06 PM
Breakthrough, led by D. Flemming Hansen @dflemminghansen.bsky.social @uclofficial.bsky.social and colleagues, addresses current challenges in obtaining high-resolution NMR spectra for aromatic residues www.ucl.ac.uk/lifesciences... #NMRnews #NMRchat #NMR 🧲
Reposted by D Flemming Hansen
Open #PhDposition: decipher the mechanisms underlying allostery.
What allows a protein to communicate over many nanometers to regulate its function? How did it evolve? What is the link to protein dynamics?
Join us to study exciting mechanisms by NMR & more.
More info attached.
phd.pages.ista.ac.at
What allows a protein to communicate over many nanometers to regulate its function? How did it evolve? What is the link to protein dynamics?
Join us to study exciting mechanisms by NMR & more.
More info attached.
phd.pages.ista.ac.at
December 22, 2024 at 11:12 AM
Open #PhDposition: decipher the mechanisms underlying allostery.
What allows a protein to communicate over many nanometers to regulate its function? How did it evolve? What is the link to protein dynamics?
Join us to study exciting mechanisms by NMR & more.
More info attached.
phd.pages.ista.ac.at
What allows a protein to communicate over many nanometers to regulate its function? How did it evolve? What is the link to protein dynamics?
Join us to study exciting mechanisms by NMR & more.
More info attached.
phd.pages.ista.ac.at
Tailored NMR experiments combined with a new DNN provide high-resolution spectra of aromatic side chains and accurate uncertainty estimates - enabling quantifications of dynamics and kinetics
doi.org/10.1126/scia...
#ScienceAdvances @crick.ac.uk @uclofficial.bsky.social @ukri.org
#NMRchat
doi.org/10.1126/scia...
#ScienceAdvances @crick.ac.uk @uclofficial.bsky.social @ukri.org
#NMRchat
A combined NMR and deep neural network approach for enhancing the spectral resolution of aromatic side chains in proteins
Combining developments in deep learning and NMR opens up opportunities like high-resolution aromatic spectra from protein samples.
doi.org
December 20, 2024 at 11:28 PM
Tailored NMR experiments combined with a new DNN provide high-resolution spectra of aromatic side chains and accurate uncertainty estimates - enabling quantifications of dynamics and kinetics
doi.org/10.1126/scia...
#ScienceAdvances @crick.ac.uk @uclofficial.bsky.social @ukri.org
#NMRchat
doi.org/10.1126/scia...
#ScienceAdvances @crick.ac.uk @uclofficial.bsky.social @ukri.org
#NMRchat
Apparent C2V symmetry and correlated motion
December 16, 2024 at 5:31 PM
Apparent C2V symmetry and correlated motion
Reposted by D Flemming Hansen
Chemical Exchange & Sparsely Populated States in #NMR by Guillaume Bouvignies from @cnrs.bsky.social @normalesup.bsky.social
December 15, 2024 at 9:00 AM
Chemical Exchange & Sparsely Populated States in #NMR by Guillaume Bouvignies from @cnrs.bsky.social @normalesup.bsky.social
All the cool details that are normally left out are revealed this morning !
Excellent tutorial on artificial intelligence in magnetic resonance presented by Ilya Kuprov at the @rsc-nmrdg.bsky.social Winter meeting #nmrchat
Excellent tutorial on artificial intelligence in magnetic resonance presented by Ilya Kuprov at the @rsc-nmrdg.bsky.social Winter meeting #nmrchat
December 13, 2024 at 10:03 AM
All the cool details that are normally left out are revealed this morning !
Excellent tutorial on artificial intelligence in magnetic resonance presented by Ilya Kuprov at the @rsc-nmrdg.bsky.social Winter meeting #nmrchat
Excellent tutorial on artificial intelligence in magnetic resonance presented by Ilya Kuprov at the @rsc-nmrdg.bsky.social Winter meeting #nmrchat
Interesting talk by Prof Poul Erik Hansen about how NMR deuterium isotope effects can report on hydrogen bonding and salt bridges at the annual NMRDG winter meeting.
@rsc-nmrdg.bsky.social
#NMRchat
@rsc-nmrdg.bsky.social
#NMRchat
December 12, 2024 at 3:39 PM
Interesting talk by Prof Poul Erik Hansen about how NMR deuterium isotope effects can report on hydrogen bonding and salt bridges at the annual NMRDG winter meeting.
@rsc-nmrdg.bsky.social
#NMRchat
@rsc-nmrdg.bsky.social
#NMRchat
Reposted by D Flemming Hansen
📣📣 XIVth international conference on #NMR a tool for biology. May 26-28, 2025 @pasteur.fr Paris, France. The registration is open 👉 www.nmr2025.conferences-pasteur.org
Coorganized with
@brukercorporation.bsky.social
Coorganized with
@brukercorporation.bsky.social
November 25, 2024 at 3:35 PM
📣📣 XIVth international conference on #NMR a tool for biology. May 26-28, 2025 @pasteur.fr Paris, France. The registration is open 👉 www.nmr2025.conferences-pasteur.org
Coorganized with
@brukercorporation.bsky.social
Coorganized with
@brukercorporation.bsky.social
Reposted by D Flemming Hansen
Hi Team #NMRchat #NMR. Happy to see you out here!
Let's start spreading the word about the ENC-ISMAR Joint Conference, April 6-10, 2025.
Oral Abstract Deadline: January 10
www.enc-conference.org/enc-ismar-2025
Let's start spreading the word about the ENC-ISMAR Joint Conference, April 6-10, 2025.
Oral Abstract Deadline: January 10
www.enc-conference.org/enc-ismar-2025
December 4, 2024 at 9:35 PM
Hi Team #NMRchat #NMR. Happy to see you out here!
Let's start spreading the word about the ENC-ISMAR Joint Conference, April 6-10, 2025.
Oral Abstract Deadline: January 10
www.enc-conference.org/enc-ismar-2025
Let's start spreading the word about the ENC-ISMAR Joint Conference, April 6-10, 2025.
Oral Abstract Deadline: January 10
www.enc-conference.org/enc-ismar-2025
Reposted by D Flemming Hansen
Are you a student or postdoc planning to attend the ENC-ISMAR Joint Conference?
We have awards and stipends available to support your travel.
All you neeed to do is apply! January 10 deadline. Giddy-up!
Details: www.enc-conference.org/Awards
#NMRchat #NMR
We have awards and stipends available to support your travel.
All you neeed to do is apply! January 10 deadline. Giddy-up!
Details: www.enc-conference.org/Awards
#NMRchat #NMR
December 6, 2024 at 4:12 PM
Are you a student or postdoc planning to attend the ENC-ISMAR Joint Conference?
We have awards and stipends available to support your travel.
All you neeed to do is apply! January 10 deadline. Giddy-up!
Details: www.enc-conference.org/Awards
#NMRchat #NMR
We have awards and stipends available to support your travel.
All you neeed to do is apply! January 10 deadline. Giddy-up!
Details: www.enc-conference.org/Awards
#NMRchat #NMR