De-Zhi Jin
@dezhijin.bsky.social
Focus on Brain & AI
A Ph.D. candidate at Beijing University of Posts and Telecommunications
A big fan of history, Chinese calligraphy, and marathon
A Ph.D. candidate at Beijing University of Posts and Telecommunications
A big fan of history, Chinese calligraphy, and marathon
👍
New today in @Nature: your visual cortex contains touch-based body maps. bit.ly/VisualBodyMaps
Your brain transforms what you see into first-person, body-referenced codes: A previously unknown bridge between vision and touch.
Your brain transforms what you see into first-person, body-referenced codes: A previously unknown bridge between vision and touch.
November 27, 2025 at 6:16 AM
👍
Reposted by De-Zhi Jin
How do dissociative states affect brain state dynamics 🧠, and do these effects vary if pharmacologically induced 💊 or due to a clinical condition 🏥?
Learn more here ⬇️
Learn more here ⬇️
Brain State Dynamics in Ketamine-Induced Dissociation Resemble Those in PTSD
Dissociation, an altered state of consciousness in which individuals feel detached from their body, environment, and sense of self, is a common feature of Post-Traumatic Stress Disorder (PTSD).…
www.bpsgos.org
November 16, 2025 at 1:00 PM
How do dissociative states affect brain state dynamics 🧠, and do these effects vary if pharmacologically induced 💊 or due to a clinical condition 🏥?
Learn more here ⬇️
Learn more here ⬇️
Reposted by De-Zhi Jin
👏 👏 👏
An Open, Fully-processed, Longitudinal Data Resource to Study Brain Development and Transdiagnostic Executive Function | bioRxiv www.biorxiv.org/content/10.1...
An Open, Fully-processed, Longitudinal Data Resource to Study Brain Development and Transdiagnostic Executive Function | bioRxiv www.biorxiv.org/content/10.1...
November 13, 2025 at 1:12 AM
👏 👏 👏
An Open, Fully-processed, Longitudinal Data Resource to Study Brain Development and Transdiagnostic Executive Function | bioRxiv www.biorxiv.org/content/10.1...
An Open, Fully-processed, Longitudinal Data Resource to Study Brain Development and Transdiagnostic Executive Function | bioRxiv www.biorxiv.org/content/10.1...
Reposted by De-Zhi Jin
Westlin and colleagues found that patients with functional neurological disorder exhibit atypical macroscale cortical organization, characterised by altered functional gradients that are linked to symptom severity.
Functional Connectivity Gradients Reveal Altered Hierarchical Cortical Organization in Functional Neurological Disorder
Neuroimaging studies of functional neurological disorder (FND), a core neuropsychiatric
condition, often rely on discrete connections or parcellations that may obscure the
brain’s functional network a...
www.biologicalpsychiatrycnni.org
October 28, 2025 at 4:35 PM
Westlin and colleagues found that patients with functional neurological disorder exhibit atypical macroscale cortical organization, characterised by altered functional gradients that are linked to symptom severity.
Reposted by De-Zhi Jin
Such a nice collection of brain-body interaction articles in the special issue of @currentbiology.bsky.social. Love the beautiful vagus nerve on the cover by Andreas Vesalius www.cell.com/current-biol...
October 22, 2025 at 6:44 PM
Such a nice collection of brain-body interaction articles in the special issue of @currentbiology.bsky.social. Love the beautiful vagus nerve on the cover by Andreas Vesalius www.cell.com/current-biol...
Reposted by De-Zhi Jin
Excited to share our work making an "allostasis-first" case that brain function is most productively framed in terms of its core regulatory function. We also introduce some new ideas in the context of metabolism and cognitive function in Alzheimer's.
www.cell.com/neuron/fullt...
www.cell.com/neuron/fullt...
October 14, 2025 at 7:56 PM
Excited to share our work making an "allostasis-first" case that brain function is most productively framed in terms of its core regulatory function. We also introduce some new ideas in the context of metabolism and cognitive function in Alzheimer's.
www.cell.com/neuron/fullt...
www.cell.com/neuron/fullt...
Reposted by De-Zhi Jin
Zhang et al. leveraged a digital twin brain model with multiscale data to demonstrate that metabolic activities in reward circuits are more prominent during early methamphetamine abstinence, while neuroplasticity is essential throughout both early and later abstinence.
Stage-Dependent Neural Mechanisms in Human Methamphetamine Abstinence: Insights From the Digital Twin Brain Model
Reward circuits are crucial in treating human methamphetamine (MA) addiction, while
the underlying mechanisms of action may vary throughout the intervention process.
This gap limits the identification...
www.biologicalpsychiatryjournal.com
October 16, 2025 at 2:22 PM
Zhang et al. leveraged a digital twin brain model with multiscale data to demonstrate that metabolic activities in reward circuits are more prominent during early methamphetamine abstinence, while neuroplasticity is essential throughout both early and later abstinence.
Reposted by De-Zhi Jin
A bit belated, but here are some new papers! first, a conceptual framework for modelling extremes in neuroimaging data
onlinelibrary.wiley.com/doi/full/10....
Great work from the inimitable Charlotte Fraza!
onlinelibrary.wiley.com/doi/full/10....
Great work from the inimitable Charlotte Fraza!
Using Extreme Value Statistics to Reconceptualize Psychopathology as Extreme Deviations From a Normative Reference Model
Overview of our approach for extreme value statistics. First, we fit a normative model to imaging phenotypes, before employing a ‘peaks-over-threshold’ approach widely used in meteorology and finance...
onlinelibrary.wiley.com
October 16, 2025 at 3:00 PM
A bit belated, but here are some new papers! first, a conceptual framework for modelling extremes in neuroimaging data
onlinelibrary.wiley.com/doi/full/10....
Great work from the inimitable Charlotte Fraza!
onlinelibrary.wiley.com/doi/full/10....
Great work from the inimitable Charlotte Fraza!
Reposted by De-Zhi Jin
Thanks for the figure @bttyeo.bsky.social 🙂🧠🙏🏽!
In this review, @lucinauddin.bsky.social and Hugh Garavan examine how task and resting-state fMRI can reveal brain-behavior relationships in youth, highlighting current controversies and challenges, outlining solutions, and proposing future directions in developmental neuroscience research.
Task and resting state fMRI modelling of brain-behavior relationships in developmental cohorts
Functional magnetic resonance imaging (fMRI) data are often used to inform individual
differences in cognitive, behavioral, and psychiatric phenotypes. These so-called
“brain-behavior” association stu...
www.biologicalpsychiatryjournal.com
October 1, 2025 at 11:09 PM
Thanks for the figure @bttyeo.bsky.social 🙂🧠🙏🏽!
Turn off Zotero. It's time to play a game.🥰
Creative experiences and brain clocks
"The higher the level of expertise and performance, the greater the delay in brain age."
Open Access
www.nature.com/articles/s41...
"The higher the level of expertise and performance, the greater the delay in brain age."
Open Access
www.nature.com/articles/s41...
Creative experiences and brain clocks - Nature Communications
Creative experiences such as dance, music, drawing, and strategy video games might preserve brain health. The authors show that regular practice or short training in these activities is linked to brains that look younger and work more efficiently.
www.nature.com
October 4, 2025 at 3:17 AM
Turn off Zotero. It's time to play a game.🥰
Reposted by De-Zhi Jin
Excited to share that our work introducing the Reproducible Brain Charts (RBC) data resource is now published in Neuron!! 🎉
📚 Read the paper: authors.elsevier.com/c/1lpaF3BtfH...
🧠 Explore the RBC dataset: reprobrainchart.github.io
📚 Read the paper: authors.elsevier.com/c/1lpaF3BtfH...
🧠 Explore the RBC dataset: reprobrainchart.github.io
(1/18) Now out on BioRxiv‼️ Reproducible Brain Charts: An open data resource for mapping brain development and its associations with mental health | doi.org/10.1101/2025...
Funded by National Institute of Mental Health (NIMH)
Funded by National Institute of Mental Health (NIMH)
Reproducible Brain Charts: An open data resource for mapping brain development and its associations with mental health
Major mental disorders are increasingly understood as disorders of brain development. Large and heterogeneous samples are required to define generalizable links between brain development and psychopat...
doi.org
September 22, 2025 at 9:51 PM
Excited to share that our work introducing the Reproducible Brain Charts (RBC) data resource is now published in Neuron!! 🎉
📚 Read the paper: authors.elsevier.com/c/1lpaF3BtfH...
🧠 Explore the RBC dataset: reprobrainchart.github.io
📚 Read the paper: authors.elsevier.com/c/1lpaF3BtfH...
🧠 Explore the RBC dataset: reprobrainchart.github.io
Reposted by De-Zhi Jin
Precision Functional Neuroimaging Reveals Individually Specific Auditory Responses in Infants | bioRxiv www.biorxiv.org/content/10.1...
August 6, 2025 at 12:24 AM
Precision Functional Neuroimaging Reveals Individually Specific Auditory Responses in Infants | bioRxiv www.biorxiv.org/content/10.1...
Reposted by De-Zhi Jin
News from ENIGMA-Epilepsy! 🧠
Our latest study links polygenic risk for TLE-HS to cortical thinning in kids—mirroring patterns in adult patients.
Early imaging-genetics insights could reveal interplay of epilepsy risk and phenotypes before symptoms emerge.
Read more 👉 doi.org/10.1093/brai...
Our latest study links polygenic risk for TLE-HS to cortical thinning in kids—mirroring patterns in adult patients.
Early imaging-genetics insights could reveal interplay of epilepsy risk and phenotypes before symptoms emerge.
Read more 👉 doi.org/10.1093/brai...
August 18, 2025 at 11:42 AM
News from ENIGMA-Epilepsy! 🧠
Our latest study links polygenic risk for TLE-HS to cortical thinning in kids—mirroring patterns in adult patients.
Early imaging-genetics insights could reveal interplay of epilepsy risk and phenotypes before symptoms emerge.
Read more 👉 doi.org/10.1093/brai...
Our latest study links polygenic risk for TLE-HS to cortical thinning in kids—mirroring patterns in adult patients.
Early imaging-genetics insights could reveal interplay of epilepsy risk and phenotypes before symptoms emerge.
Read more 👉 doi.org/10.1093/brai...
Reposted by De-Zhi Jin
Interested in Network hubs, cortical hierarchies, and gradients? Ever wonder where they come from? Check our latest review, where we cover different approaches to mapping hubs, models for their evolution, and mechanisms for how they develop:
osf.io/preprints/os...
osf.io/preprints/os...
August 17, 2025 at 4:27 AM
Interested in Network hubs, cortical hierarchies, and gradients? Ever wonder where they come from? Check our latest review, where we cover different approaches to mapping hubs, models for their evolution, and mechanisms for how they develop:
osf.io/preprints/os...
osf.io/preprints/os...
Reposted by De-Zhi Jin
Functional connectivity heterogeneity and consequences for clinical and cognitive prediction: Stage 2 registered report | Imaging Neuroscience | MIT Press direct.mit.edu/imag/article...
Functional connectivity heterogeneity and consequences for clinical and cognitive prediction: Stage 2 registered report
Abstract. Functional connectivity is frequently used to assess dynamic brain functioning and predict individual differences in behavioral outcomes, such as psychopathology. Inferences from functional ...
direct.mit.edu
August 14, 2025 at 6:16 AM
Functional connectivity heterogeneity and consequences for clinical and cognitive prediction: Stage 2 registered report | Imaging Neuroscience | MIT Press direct.mit.edu/imag/article...
Reposted by De-Zhi Jin
I still get chills
Meet Mike
*30+ years severe depression
*first hospitalized @ 13y
*20 meds
*3 rounds of ECT
*2 near-fatal suicide attempts
Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE
see videos, read paper, follow thread
doi.org/10.31234/osf...
Meet Mike
*30+ years severe depression
*first hospitalized @ 13y
*20 meds
*3 rounds of ECT
*2 near-fatal suicide attempts
Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE
see videos, read paper, follow thread
doi.org/10.31234/osf...
August 10, 2025 at 6:23 PM
I still get chills
Meet Mike
*30+ years severe depression
*first hospitalized @ 13y
*20 meds
*3 rounds of ECT
*2 near-fatal suicide attempts
Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE
see videos, read paper, follow thread
doi.org/10.31234/osf...
Meet Mike
*30+ years severe depression
*first hospitalized @ 13y
*20 meds
*3 rounds of ECT
*2 near-fatal suicide attempts
Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE
see videos, read paper, follow thread
doi.org/10.31234/osf...
Reposted by De-Zhi Jin
Polygenic scores for autism are associated with reduced neurite density in adults and children from the general population | Molecular Psychiatry www.nature.com/articles/s41...
July 11, 2025 at 2:39 AM
Polygenic scores for autism are associated with reduced neurite density in adults and children from the general population | Molecular Psychiatry www.nature.com/articles/s41...
🧐four subnetworks within the Action Mode Network related to decisions, action implementation, feedback, and the bodily self
We have argued that the brain’s Action Mode Network controls functions required for goal-directed behavior. www.nature.com/articles/s41...
Now, in new work, we show that AMN contains distinct subnetworks for making decisions, implementing actions, and processing feedback. doi.org/10.1073/pnas...
Now, in new work, we show that AMN contains distinct subnetworks for making decisions, implementing actions, and processing feedback. doi.org/10.1073/pnas...
July 11, 2025 at 1:10 AM
🧐four subnetworks within the Action Mode Network related to decisions, action implementation, feedback, and the bodily self
Reposted by De-Zhi Jin
We have argued that the brain’s Action Mode Network controls functions required for goal-directed behavior. www.nature.com/articles/s41...
Now, in new work, we show that AMN contains distinct subnetworks for making decisions, implementing actions, and processing feedback. doi.org/10.1073/pnas...
Now, in new work, we show that AMN contains distinct subnetworks for making decisions, implementing actions, and processing feedback. doi.org/10.1073/pnas...
July 10, 2025 at 7:52 PM
We have argued that the brain’s Action Mode Network controls functions required for goal-directed behavior. www.nature.com/articles/s41...
Now, in new work, we show that AMN contains distinct subnetworks for making decisions, implementing actions, and processing feedback. doi.org/10.1073/pnas...
Now, in new work, we show that AMN contains distinct subnetworks for making decisions, implementing actions, and processing feedback. doi.org/10.1073/pnas...
Reposted by De-Zhi Jin
Hypermodularity and community detection in hypergraphs arxiv.org/abs/2412.06935
Hypermodularity and community detection in hypergraphs
Numerous networked systems feature a structure of nontrivial communities, which often correspond to their functional modules. Such communities have been detected in real-world biological, social and t...
arxiv.org
July 9, 2025 at 6:42 AM
Hypermodularity and community detection in hypergraphs arxiv.org/abs/2412.06935
Reposted by De-Zhi Jin
Alert!!!!
“An Action Networks Model for Pain”
We propose a new model for chronic pain — and highlight two functionally connected cortical networks that could revolutionize how we treat it.
👉 thread below 🧵
osf.io/preprints/ps...
“An Action Networks Model for Pain”
We propose a new model for chronic pain — and highlight two functionally connected cortical networks that could revolutionize how we treat it.
👉 thread below 🧵
osf.io/preprints/ps...
June 26, 2025 at 1:29 PM
Alert!!!!
“An Action Networks Model for Pain”
We propose a new model for chronic pain — and highlight two functionally connected cortical networks that could revolutionize how we treat it.
👉 thread below 🧵
osf.io/preprints/ps...
“An Action Networks Model for Pain”
We propose a new model for chronic pain — and highlight two functionally connected cortical networks that could revolutionize how we treat it.
👉 thread below 🧵
osf.io/preprints/ps...
Reposted by De-Zhi Jin
NetNeuroLab posters + talks at @ohbmofficial.bsky.social
synapse types! neurotransmission connectomes! mouse maps! neuromorphic networks! generative models! neuropeptides! ⤵️
synapse types! neurotransmission connectomes! mouse maps! neuromorphic networks! generative models! neuropeptides! ⤵️
June 23, 2025 at 2:57 PM
NetNeuroLab posters + talks at @ohbmofficial.bsky.social
synapse types! neurotransmission connectomes! mouse maps! neuromorphic networks! generative models! neuropeptides! ⤵️
synapse types! neurotransmission connectomes! mouse maps! neuromorphic networks! generative models! neuropeptides! ⤵️
From this, what is the neural mechanism by which humans distinguish virtual from reality?
Real and imagined images are processed using the same systems in the brain, yet most people can distinguish between the two. Now neuroscientists have identified two brain regions that keep imagined images separate from reality.
https://go.nature.com/4jRSfIm
https://go.nature.com/4jRSfIm
How the brain separates real images from those it imagines
Nature - Neuroscientists have found the regions that keep them apart.
go.nature.com
June 14, 2025 at 3:20 PM
From this, what is the neural mechanism by which humans distinguish virtual from reality?
Reposted by De-Zhi Jin
Do girls and boys really differ in their mathematical skills? A recent @nature.com paper by @standehaene.bsky.social et al shows that French boys and girls enter school with similar abilities, but after just four months, boys pull ahead 🧪 www.nature.com/articles/s41...
Rapid emergence of a maths gender gap in first grade - Nature
Boys and girls exhibit very similar maths scores upon school entry, but a gender gap in favour of boys becomes highly significant after 4 months of schooling, which increases with years of schooling,&...
www.nature.com
June 13, 2025 at 1:33 AM
Do girls and boys really differ in their mathematical skills? A recent @nature.com paper by @standehaene.bsky.social et al shows that French boys and girls enter school with similar abilities, but after just four months, boys pull ahead 🧪 www.nature.com/articles/s41...