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cpuentelelievre.bsky.social
Caroline Puente-Lelievre
@cpuentelelievre.bsky.social
44 followers 54 following 27 posts
Research fellow @aucklanduni.bsky.social
Structural phylogenetics #strphylo protein evolution, plant systematics
Posts Replies Media Videos
cpuentelelievre.bsky.social
From AI to ancestral proteins, the #APSPM2026 speaker lineup brings protein evolution research together in one place. Check out the list of confirmed speakers here:
biosig.lab.uq.edu.au/strphy26/spe...
Brisbane + online
Feb 2026
Free registration
@official-smbe.bsky.social
APSPM 2026: Structural Phylogenetics Meeting
A pivotal SMBE regional meeting in Brisbane on the interface of protein structure, function, and evolution.
biosig.lab.uq.edu.au
November 14, 2025 at 4:58 AM
cpuentelelievre.bsky.social
Protein evolution underpins the principles that govern molecular function. Investigating how protein structure and function evolve will enable protein design to genuinely transform medicine.
rcsbpdb.bsky.social RCSB Protein Data Bank @rcsbpdb.bsky.social · 11d
AI in Protein Design: Hype vs. Reality Explained by David Baker
In this GEN interview, he emphasizes that designing new proteins from scratch is now a reality. Whether AI transforms medicine will require improving our understanding of biology's complexity
AI in Protein Design: Hype vs. Reality Explained by David Baker
In this GEN interview, Nobel Laureate David Baker, PhD, emphasizes that designing proteins from scratch is reality and unpacks what's needed for AI to transform medicine.
www.genengnews.com
November 7, 2025 at 3:58 AM
Reposted by Caroline Puente-Lelievre
ebi.embl.org
UniProt is changing its reference proteomes resource.

Reference proteomes will remain in UniProtKB, while others will move to UniParc.

Read more about these changes:
www.ebi.ac.uk/about/news/u...

🧬 🖥️

Uniprot is a collaboration between EMBL-EBI, @sib.swiss & the Protein Information Resource.
Changes to UniProt proteomes
UniProt, the data resource for protein sequence and function information, is making major changes to its proteomes resource and to the UniProt Knowledgebase. UniProt has developed a new workflow that ...
www.ebi.ac.uk
November 4, 2025 at 9:58 AM
cpuentelelievre.bsky.social
Looking forward to seeing David Moi's talk about Foldtree and the upcoming Foldtree II at #APSPM2026 in sunny Brisbane.

biosig.lab.uq.edu.au/strphy26/spe...

@official-smbe.bsky.social
November 7, 2025 at 3:24 AM
Reposted by Caroline Puente-Lelievre
official-smbe.bsky.social
Registration is now open for SMBE 2026!

Head over to the registration page to find all the details and secure your spot 🏃‍♀️

📝 smbe2026.org/registration
🐦 Early-bird deadline: March 31, 2026

If you are an active member of the SMBE you can register for the meeting with discounts.

#SMBE2026
SMBE 2026 | Registration is open
November 3, 2025 at 11:05 AM
cpuentelelievre.bsky.social
I’m so excited and impressed with the abstracts we have received so far. Looking forward to the talks!
November 3, 2025 at 5:48 AM
cpuentelelievre.bsky.social
February 2026 is shaping up to be the month for protein science down under!

Lorne (Feb 8–12) @lorneproteins.bsky.social

APSPM 2026, Brisbane (Feb 15–18)
biosig.lab.uq.edu.au/strphy26/str...

Two meetings and a summer of great science!

@strphy.bsky.social

@official-smbe.bsky.social
October 30, 2025 at 3:49 AM
cpuentelelievre.bsky.social
You can become an expert after the meeting!
@official-smbe.bsky.social
strphy.bsky.social Structural Phylogenetics (StrPhy) @strphy.bsky.social · 15d
#APSPM2026 is open to anyone curious about combining protein structure and evolution. Learn where to start in our workshops and discover how structure meets phylogenetics.

Feb 15 - 18, 2026
Brisbane, Australia
Register here: biosig.lab.uq.edu.au/strphy26/reg...
(in-person only)
October 30, 2025 at 1:00 AM
cpuentelelievre.bsky.social
We can’t wait to welcome you to sunny Brisbane. Home to world-class research and a vibrant scientific community. Join us at the University of Queensland for #APSPM2026 to discuss how protein structure and evolution come together #StrPhy26
October 27, 2025 at 5:02 AM
Reposted by Caroline Puente-Lelievre
compoundchem.com
It's #NationalPumpkinDay! 🎃

Why are pumpkins orange, and what do pumpkins have to do with pumpkin spice? Here are the chemical answers in @cenmag.bsky.social: cen.acs.org/articles/93/...

#ChemSky 🧪
Infographic on the chemistry of pumpkins. The colour of pumpkins is due to carotenoid compounds such as beta-carotene, the same compound that gives carrots their orange colour. The vegetal aroma of pumpkins is mainly due to cis-3-hexen-1-ol, along with other six-carbon alcohols and aldehydes. Canned pumpkin is often not the same type of pumpkin as those used for carving, and consequently, the aroma compounds differ, including burnt-smelling 2-methylbutanal, coffee furanone, and furfural. Pumpkin spice flavour has little to do with pumpkin and more to do with the spices added, including cinnamon, nutmeg and clove.
October 26, 2025 at 8:50 PM
Reposted by Caroline Puente-Lelievre
strphy.bsky.social
Abstract submissions are open for #APSPM2026!
🗓️ Deadline: Nov 28, 2026
📍 Brisbane + online
🎓 Travel grants for students & ECRs
Join us to explore how protein structures and AI are reshaping evolutionary biology.

@official-smbe.bsky.social

#StrPhy26 #StrPhy
APSPM 2026: Structural Phylogenetics Meeting
A pivotal SMBE regional meeting in Brisbane on the interface of protein structure, function, and evolution.
biosig.lab.uq.edu.au
October 24, 2025 at 4:06 AM
Reposted by Caroline Puente-Lelievre
official-smbe.bsky.social
The conference will be held on the beautiful St Lucia campus of The University of Queensland. Plenary speakers are @joannamasel.bsky.social (University of Arizona, USA) and Nicholas Matzke (University of Auckland, NZ).

Registration is free, but spaces are limited to 50 in-person attendees.
October 22, 2025 at 10:17 AM
Reposted by Caroline Puente-Lelievre
official-smbe.bsky.social
Structural phylogenetics is poised to reshape our understanding of molecular evolution. While the availability of structural data has exploded, its integration into evolutionary analysis has yet to reach its full potential. This meeting provides a timely forum to explore this frontier.
October 22, 2025 at 10:17 AM
Reposted by Caroline Puente-Lelievre
official-smbe.bsky.social
We are excited to announce APSPM 2026 - the SMBE Australasian Protein Structural Phylogenetics Meeting!

🗓️ 15-18 Feb. 2026
🌏 Brisbane, Australia

🔗 biosig.lab.uq.edu.au/strphy26/

📄 Abstract submission: 28.11.2025
✈️ Travel grant application: 28.11.2025
✏️ Registration: 15.01.2026

#StrPhy26
APSPM 2026: Structural Phylogenetics Meeting
A pivotal SMBE regional meeting in Brisbane on the interface of protein structure, function, and evolution.
biosig.lab.uq.edu.au
October 22, 2025 at 10:17 AM
cpuentelelievre.bsky.social
Registration is now open! Limited spots so register fast. We also have generous travel grants. We’d love to see attendees from all career stages and backgrounds. #StrPhy26 @official-smbe.bsky.social
October 22, 2025 at 8:41 AM
cpuentelelievre.bsky.social
New in the #StructuralPhylogenetics special section:
Dixson et al. show that structural and physicochemical features of proteins uncover remote evolutionary relationships and provide a new toolset to revisit mitochondrial enzyme evolution.
@genomebiolevol.bsky.social
Inference of Cytochrome P450 Evolutionary History Using Structural and Physicochemical Metrics
Abstract. Cytochrome P450s are a superfamily of heme-binding monooxygenases involved with the detoxification of intrinsic and extrinsic toxins. They are ne
academic.oup.com
October 15, 2025 at 10:52 PM
cpuentelelievre.bsky.social
Follow this account for updates on the upcoming SMBE Australasian Protein Structural Phylogenetics Meeting #APSPM
proteinmechanic.bsky.social Ashar Malik @proteinmechanic.bsky.social · Oct 9
We’ve set up a dedicated Bluesky space for structural phylogenetics: @strphy.bsky.social. Follow for community updates.

#StrPhy #StructuralPhylogenetics
October 10, 2025 at 10:15 PM
cpuentelelievre.bsky.social
The case for useless knowledge by Betül Kaçar. In this 3 minute video she explains why the simple act of being curious and asking questions (without needing a reason) is one of the most powerful things a human can do. www.youtube.com/watch?v=J2k3...
The case for useless knowledge | Betül Kaçar
YouTube video by The Well
www.youtube.com
October 8, 2025 at 10:01 PM
cpuentelelievre.bsky.social
The next NZ Phylogenomics Meeting will be in Waiheke Island (a short ferry trip away from Auckland City) on February 10 - 13, 2026. It combines maths, computer science, statistics, and biology for phylogenetics, genome analysis and molecular evolution. compevol.github.io/Waiheke2026/
Picture of the sea from Waiheke Island.
October 8, 2025 at 9:50 PM
cpuentelelievre.bsky.social
Save the date! the SMBE Australasian Protein Structural Phylogenetics Meeting #APSPM will take place on 15 - 18 February, 2026 at the University of Queensland in Brisbane, Australia. More details coming up soon. Registration will be free thanks to the generous support of @official-smbe.bsky.social
October 7, 2025 at 10:46 PM
cpuentelelievre.bsky.social
The protein structure era!
compoundchem.com Compound Interest | Chemistry infographics @compoundchem.com · Oct 7
With the 2025 Nobel Prize in Chemistry being announced tomorrow, here's a reminder of the research on protein structure prediction that won last year's prize: www.compoundchem.com/2024/10/10/2...

#ChemSky 🧪
The 2024 Nobel Prize in Chemistry was awarded to David Baker for computational protein design and to Demis Hassabis and John M. Jumper for protein structure prediction. Proteins are important biological molecules formed from 20 naturally occurring amino acids. Proteins form folded 3D structures which are key to their function and properties, but the exact way in which they fold is hard to predict. In 2020, Demis Hassabis, John Jumper and their co-workers unveiled an artificial intelligence model called AlphaFold2 to predict 3D folded structures of proteins. David Baker developed Rosetta, software that also attempts to predict protein structures, and used it to start with a protein structure and use the software to work out its amino acid sequence. Predicting and designing protein structures benefits the design of protein-based drugs, sensors, vaccines, catalysts, and more. It also aids our understanding of existing proteins and how they interact with other molecules.
October 7, 2025 at 10:36 PM
cpuentelelievre.bsky.social
The earliest animals may have been sea sponges. MIT team found chemical fossils (>541M yrs old steranes) pointing to ancient demosponges.
October 1, 2025 at 3:23 AM
Reposted by Caroline Puente-Lelievre
smbe-idea.bsky.social
LAST CHANCE FOR PROPOSAL SUBMISSION!

SMBE IDEA 2026
Supporting intiatives tackling inequities in evolutionary biology

We have funding in:
💡 Inclusion, Diversity, Equity and Access ($25k)
🪂 Non-Parachute Science ($10k)
🗣️ Outreach ($10k)

📅 Deadline: Oct 10, 2025
docs.google.com/forms/d/e/1F...
SMBE IDEA 2026 call for proposals
SMBE, through the IDEA (Inclusion, Diversity, Equity and Access) task force, aims to address systemic racism, sexism, colonialism and other exclusion in our SMBE society. With this in mind, SMBE has m...
docs.google.com
September 30, 2025 at 2:14 PM
cpuentelelievre.bsky.social
Open-source GPU-accelerated MMseqs2 makes protein homology search & structure prediction a lot faster. It will redefine the way we handle large-scale sequence & structure analyses.
martinsteinegger.bsky.social Martin Steinegger 🇺🇦 @martinsteinegger.bsky.social · Sep 21
MMseqs2-GPU sets new standards in single query search speed, allows near instant search of big databases, scales to multiple GPUs and is fast beyond VRAM. It enables ColabFold MSA generation in seconds and sub-second Foldseek search against AFDB50. 1/n
📄 www.nature.com/articles/s41...
💿 mmseqs.com
GPU-accelerated homology search with MMseqs2 - Nature Methods
Graphics processing unit-accelerated MMseqs2 offers tremendous speedups for homology retrieval from metagenomic databases, query-centered multiple sequence alignment generation for structure predictio...
www.nature.com
September 24, 2025 at 4:00 AM
cpuentelelievre.bsky.social
A wikipedia page on structural phylogenetics! en.wikipedia.org/wiki/Protein...
Protein structural phylogenetics - Wikipedia
en.wikipedia.org
September 24, 2025 at 3:54 AM