Jordan
cocktailchem.bsky.social
Jordan
@cocktailchem.bsky.social
Reposted by Jordan
Fascinating drug discovery story here
#chemchat #chemsky
New from my lab on bioRxiv - we found an existing drug that appears to be safe in humans that selectively kills chemotherapy-resistant cancer cells.
A clinical-stage oncology compound selectively targets drug-resistant cancers https://www.biorxiv.org/content/10.1101/2025.11.26.690878v1
December 1, 2025 at 9:53 PM
Reposted by Jordan
when we talk about elite failure, this is a big part of it, at the leadership level in education and in business, too many executives simply refuse to exercise any kind of judgment whatsoever, everyone wants the perks, no one wants the responsibility
November 30, 2025 at 9:16 PM
Reposted by Jordan
I HAVE NO IDEA WHO NEEDS TO HEAR THIS BUT DUMBARTON OAKS' MEDIEVAL LIBRARY IS HAVING A 30% OFF SALE.

IF YOU WANT TO GET INTO THE WEIRDASS SHIT I STUDY, THIS IS AN INCREDIBLE OPPORTUNITY.

(You need to order from the publisher's website directly)
November 30, 2025 at 4:54 AM
Reposted by Jordan
1/2 I find myself having to make this point more often.

The muddying of distinction between the bullshit engine and genuinely life-saving applications of ML / AI is intentional. It allows the people trying to sell you genAI to claim noble intent and dismiss legitimate concerns.
Having AI crammed down our throats is bullshit, but machine learning has some real uses in science. This awesome page shows experimental cyclone track forecasts from Google DeepMind and Google Research's AI weather models, along with forecasts from ECMWF. 😍

deepmind.google.com/science/weat...
November 30, 2025 at 8:14 AM
This makes me think of early Metric tracks.

youtu.be/L-pfSMHO3F8
Pixel Grip - Work or Shut Up (Official Lyric Video)
YouTube video by Pixel Grip
youtu.be
November 30, 2025 at 3:19 AM
Reposted by Jordan
It’s so very easy to weaponize uncertainty:“We just can’t know if it’s safe, so better not to act at all”. Everyone is glad when the precautionary principle is used as a cudgel against something they already dislike, but the problem comes when it’s used to ban something you know works-like vaccines🤓
November 29, 2025 at 11:16 PM
Reposted by Jordan
Black Friday reminder - that product with a great price being sold by a company with a name that's just a bunch of random letters may end up on our website someday because it explodes.
November 28, 2025 at 4:05 PM
Reposted by Jordan
Because what is America if not seeing something you want and simply using every available option to get it????
November 27, 2025 at 5:57 PM
Reposted by Jordan
A roll of aluminum foil is maybe one of the most incredible things you will ever hold in your life. That was a creation for kings and you wrap it around food and throw it in the dumpster. You talk about planes as aluminum cans, as if both are not one of the most incredible creations in history.
November 27, 2025 at 5:50 PM
Reposted by Jordan
I htink I read every book with Jody Lee's cover art on it when I was a teenager. Think Mercedes Lacky, Lloyd Alexander, Michelle Sagara & more of your favs.

She has scanned & put up her art for sale fineartamerica.com/profiles/3-j...
November 26, 2025 at 9:33 PM
@golikehellmachine.com New cursed object dropped.
Society is a construct. You can just ask someone to do a ska cover of Faith of the Heart and they'll say "$300 please" and you give it to them and then you have it.

Everyone, give
@skatunenetwork.bsky.social
your money. They deserve it.
November 26, 2025 at 6:19 PM
Reposted by Jordan
i got tired of "how to read more" advice from people who are book critics and don't own tvs and live in monasteries with no wifi, so here is some advice from someone with a terminal case of internet brain www.shesabeast.co/how-to-read-...
how to read more
from someone who actually struggles
www.shesabeast.co
November 26, 2025 at 4:25 PM
Reposted by Jordan
also if I can Stoicism post just a bit: this is also what memento mori is for. you are going to die someday - do you really imagine than one of your regrets will be that you didn't organize more of your life around what random Redditors think is gay?

bsky.app/profile/maxk...
So many men go through life like that. You can play poker because it's right-coded, you can't enjoy fruity alcoholic drinks because they're women-coded, you can't lick an ice cream cone because it's gay-coded. All day, every day, choosing and judging things based on coding for narrow norms.
November 26, 2025 at 4:06 PM
A friend once told me that I was more myself than anyone else he knew.
What is the best compliment you ever received? Putting aside whether or not you believed it.
November 26, 2025 at 4:44 PM
Reposted by Jordan
Frankly if you think that “cleverly satirizing a troll” is a compelling way to post on here I’m going to assume you are a boring person with uninteresting views and mute you
Friends,

If I have never communicated with you before about anything ever,

And your first communication with me about anything ever is extremely troll-like,

My first thought is going to be "that's a troll," not "that person is on my side but is cleverly perfectly satirizing a troll"
November 26, 2025 at 4:17 PM
Reposted by Jordan
Glad to see this @wired.com guide on high quality masks! A KN95 can help protect you and your loved ones from COVID-19 and other airborne viruses, especially during this busy travel season. I only wish Wired wrote about the pandemic in the present tense 🙏😷

www.wired.com/story/best-d...
15 Good N95, KF94, and KN95 Face Masks to Buy Right Now
Flu season is here. These are the best disposable face coverings we’ve tested—and where you can find them.
www.wired.com
November 25, 2025 at 2:18 AM
Reposted by Jordan
“They are drunk and silver is stolen” covers so much.
Well this 2,600-year-old clay letter was a journey.

It comes from the archive of a goldsmith named Nabû-zeru-iddin in the heart of ancient Assyria. We’ve got someone left on read, a lawsuit, a mean step-mom, and people who get drunk and steal silver.
November 24, 2025 at 10:28 AM
Reposted by Jordan
Gyms are not therapy either.
Children are not therapy
Wives are not therapy
Marriage is not therapy

only therapy is therapy
November 24, 2025 at 7:25 PM
Reposted by Jordan
This is going around a lot today and, man... the last six months of my mom's life were absolutely *miserable* for me in a way they did not have to be, in a society that valued help and care. But the sandwich generation thing is real and is absolutely, miserably awful.
November 24, 2025 at 4:52 PM
Reposted by Jordan
Just a friendly reminder as we go into the holidays:

Folks don't have to explain to you why they don't drink.

If you offer them a drink and they decline, don't ask them why. It's not your business.

Just offer them something without alcohol to drink instead. And move on.
November 23, 2025 at 8:04 PM
Reposted by Jordan
You in my business now… don’t do that
Twitter accounts are based in Russia. BlueSky accounts are based in homes with, frankly, too many books, plants, obsolete cables, and pieces of rustic pottery, that could do with a bit of a tidying up, to be honest.
November 23, 2025 at 11:04 PM
Last year we did a big order from a local food truck that does barbecue tacos. On top of a few veggie dishes it was both plenty to eat and minimal work while tasting better than any turkey we could have done.
Actually in the spirit of this conversation, what’s a decision you made about a past Thanksgiving holiday that really paid off? I think people often feel trapped by their lives. Sharing our experiences can liberate us from that sense of claustrophobia.
On the most recent episode of VIBE CHECK, we answer listener questions about Thanksgiving, most importantly “do you go celebrate with the family members you don’t even like?”
November 23, 2025 at 8:02 PM
I have left places at exactly the right time for the last two decades.
What’s the lore behind choosing your career path ?
November 23, 2025 at 3:44 AM