Brandon Findlay
chemtips.bsky.social
Brandon Findlay
@chemtips.bsky.social
Because organic chemistry is hard enough. Author of chemtips.wordpress.com
Associate Professor, Concordia University
Lab website is findlaylab.ca
If you remove the "mab" suffix, most antibody drugs are great names for demons:

Atezolizu
Basilixi
Drozitu
Ozanezu
Porgavixi
November 5, 2025 at 8:17 PM
@cenmag.bsky.social Pet spa? Really?
It's been ten minutes and my wife is still giggling.
October 23, 2025 at 10:51 PM
Bacteria exposed to antibiotics become resistant, that's the core of the #AMR crisis. We figured out how to expose them to antibiotics and evolve susceptibility instead. @farhanrc.bsky.social shows how, in our latest paper.
academic.oup.com/jac/advance-...
Sequential antibiotic exposure restores antibiotic susceptibility
AbstractBackground. The prevalence of antibiotic resistance continues to rise, rendering many valuable antimicrobial drugs ineffective. Pairwise cyclic ant
academic.oup.com
October 9, 2025 at 2:31 PM
Reposted by Brandon Findlay
We’re proud to showcase the work of Brandon Findlay, Associate Professor in #Chemistry & #Biochemistry at @concordia.ca whose lab is tackling one of today’s most pressing #GlobalHealth challenges: #AntimicrobialResistance.

#HealthResearch #AntibioticResistance

www.youtube.com/watch?v=MGxV...
Meet The Researcher: Brandon Findlay, Chemistry & Biochemistry, Antimicrobial Resistance Researcher
YouTube video by Concordia University School of Health
www.youtube.com
September 11, 2025 at 4:04 PM
The Findlay lab turned 10 years old today! What an incredible journey it's been.
August 1, 2025 at 1:41 PM
New paper from the lab!
Evolving bacteria in the lab is a great way to understand #AMR. But, does it matter what evolution platform you use? Yes.

@farhanrc.bsky.social showed different platforms select different evolutionary paths. Read more at IJAA:
www.sciencedirect.com/science/arti...
#microsky
Large scale laboratory evolution uncovers clinically relevant collateral antibiotic sensitivity
The increasing prevalence of antibiotic resistance is a critical challenge, necessitating the development of strategies to mitigate the evolution of r…
www.sciencedirect.com
July 2, 2025 at 4:44 PM
Reposted by Brandon Findlay
🚨NEW PREPRINT ALERT:

In this paper, Jacob and Suzana from the Auclair lab investigate how Salmonella Typhimurium adapts to growing on itaconate, with detailed metabolic and genomic studies.

Many thanks to our collaborators at McGill and Concordia! (Details below) #chemsky

doi.org/10.1101/2025...
June 21, 2025 at 11:57 AM
The latest work from my lab is out in @molbioevol.bsky.social! @farhanrc.bsky.social evolved bacteria right into evolutionary traps, reverting antibiotic-resistant strains back into sensitive ones. #microsky academic.oup.com/mbe/advance-...
Tripartite loops reverse antibiotic resistance
Abstract. Antibiotic resistance threatens to undo many of the advancements of modern medicine. A slow antibiotic development pipeline makes it impossible t
academic.oup.com
June 6, 2025 at 5:33 PM
Toxin-antitoxin systems are weird, but seem pretty effective. So where are the plasmids with 20+ toxin/antitoxin pairs? The logic that makes one pair adaptive should be true for 2 pairs, 3 pairs, n+1 pairs...
#microsky
March 11, 2025 at 7:58 PM
This seems like a fitting first post. My lab has just published a paper on the evolution of resistance to Octyl-tridecaptin A1!

This antibiotic is tough to evolve resistance against. To crack it we had to optimize SAGE, our lab evolution system.
www.sciencedirect.com/science/arti...

#AMR #microsky
www.sciencedirect.com
January 14, 2025 at 5:40 PM