Chao Yang
@chaooo.bsky.social
Associate Professor, Shanghai Institute of Materia Medica.
Bacterial genome evolution, genomic epidemiology, Vibrio
Bacterial genome evolution, genomic epidemiology, Vibrio
Reposted by Chao Yang
Combination of large-scale phylogenomic analysis, mouse lethality experiments and bacterial growth assays shows sheds light on how a pandemic clone of Vibrio parahaemolyticus was able to spread worldwide
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Wave succession in the pandemic clone of Vibrio parahaemolyticus driven by gene loss - Nature Ecology & Evolution
A combination of large-scale phylogenomic analysis, mouse lethality experiments and bacterial growth assays shows that gene loss in the putrescine utilization pathway has enhanced biofilm formation an...
www.nature.com
August 27, 2025 at 11:04 AM
Combination of large-scale phylogenomic analysis, mouse lethality experiments and bacterial growth assays shows sheds light on how a pandemic clone of Vibrio parahaemolyticus was able to spread worldwide
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Chao Yang
Beautiful work on the emergence of the pandemic clone of V. parahaemolyticus
Combination of large-scale phylogenomic analysis, mouse lethality experiments and bacterial growth assays shows sheds light on how a pandemic clone of Vibrio parahaemolyticus was able to spread worldwide
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Wave succession in the pandemic clone of Vibrio parahaemolyticus driven by gene loss - Nature Ecology & Evolution
A combination of large-scale phylogenomic analysis, mouse lethality experiments and bacterial growth assays shows that gene loss in the putrescine utilization pathway has enhanced biofilm formation an...
www.nature.com
August 27, 2025 at 11:21 AM
Beautiful work on the emergence of the pandemic clone of V. parahaemolyticus
Our “Less is more” story is out! 🚀 We reveal how gene loss shaped the adaptive evolution of pandemic Vibrio parahaemolyticus, highlight a potentially general mechanism across bacteria. Huge thanks @danielfalush.bsky.social @campy-bara.bsky.social @jaimemurtaza.bsky.social & all coauthors
Combination of large-scale phylogenomic analysis, mouse lethality experiments and bacterial growth assays shows sheds light on how a pandemic clone of Vibrio parahaemolyticus was able to spread worldwide
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Wave succession in the pandemic clone of Vibrio parahaemolyticus driven by gene loss - Nature Ecology & Evolution
A combination of large-scale phylogenomic analysis, mouse lethality experiments and bacterial growth assays shows that gene loss in the putrescine utilization pathway has enhanced biofilm formation an...
www.nature.com
August 27, 2025 at 1:06 PM
Our “Less is more” story is out! 🚀 We reveal how gene loss shaped the adaptive evolution of pandemic Vibrio parahaemolyticus, highlight a potentially general mechanism across bacteria. Huge thanks @danielfalush.bsky.social @campy-bara.bsky.social @jaimemurtaza.bsky.social & all coauthors
Reposted by Chao Yang
How to get introgressed fragments in genomic data? Everything you always wanted to know you find in our review in @cp-trendsgenetics.bsky.social, led by Xin Huang:
doi.org/10.1016/j.ti...
doi.org/10.1016/j.ti...
July 24, 2025 at 2:04 AM
How to get introgressed fragments in genomic data? Everything you always wanted to know you find in our review in @cp-trendsgenetics.bsky.social, led by Xin Huang:
doi.org/10.1016/j.ti...
doi.org/10.1016/j.ti...
What drove the post-pandemic global pertussis upsurge? Immunity debt? Waning immunity? Other factors?
Our recent study highlights the key role of pathogen evolution.
We also identified the global spread of a drug-resistant clone, MR-MT28, which warrants coordinated global surveillance.
Our recent study highlights the key role of pathogen evolution.
We also identified the global spread of a drug-resistant clone, MR-MT28, which warrants coordinated global surveillance.
Adaptive evolution and global spread of macrolide-resistant Bordetella pertussis during the post-pandemic pertussis resurgence
Pertussis resurgence following the COVID-19 pandemic remains poorly understood. Here, we integrate global surveillance data with 8,117 Bordetella pertussis genomes from 35 countries to investigate the...
www.medrxiv.org
July 21, 2025 at 10:42 AM
What drove the post-pandemic global pertussis upsurge? Immunity debt? Waning immunity? Other factors?
Our recent study highlights the key role of pathogen evolution.
We also identified the global spread of a drug-resistant clone, MR-MT28, which warrants coordinated global surveillance.
Our recent study highlights the key role of pathogen evolution.
We also identified the global spread of a drug-resistant clone, MR-MT28, which warrants coordinated global surveillance.
Reposted by Chao Yang
Molassodon! Excited to post my research group's first laboratory project. We identify a phenotype and a putative ecological strategy for the Molassodon ecospecies of Vibrio parahamolyticus, thanks to the hard work of our lab team led by @campy-bara.bsky.social www.biorxiv.org/content/10.1...
June 30, 2025 at 4:24 AM
Molassodon! Excited to post my research group's first laboratory project. We identify a phenotype and a putative ecological strategy for the Molassodon ecospecies of Vibrio parahamolyticus, thanks to the hard work of our lab team led by @campy-bara.bsky.social www.biorxiv.org/content/10.1...
Reposted by Chao Yang
Delighted to present our Macrogenetics atlas of prokaryotes. www.biorxiv.org/content/10.1... This is a herculean effort from Chao Yang, which has a previous existence as a preprint first posted in 2018 "why panmictic bacteria are rare?" www.biorxiv.org/content/10.1...
Macrogenetic atlas of prokaryotes
Macrogenetics investigates the patterns and predictors of intraspecific genetic variation across diverse taxa, offering a framework to address longstanding evolutionary hypotheses. Here, we present a ...
www.biorxiv.org
February 28, 2025 at 6:06 AM
Delighted to present our Macrogenetics atlas of prokaryotes. www.biorxiv.org/content/10.1... This is a herculean effort from Chao Yang, which has a previous existence as a preprint first posted in 2018 "why panmictic bacteria are rare?" www.biorxiv.org/content/10.1...