Vanesa Cepas López
@cepaslopez.bsky.social
MSCA Postdoctoral fellow at University of Turin/Candiolo Cancer Institute.
Interested in redox biology, cell plasticity and cancer.
🐣 Asturies 🏠 Torino
Interested in redox biology, cell plasticity and cancer.
🐣 Asturies 🏠 Torino
🚨ECRs apply to the PhD Symposium! Best presentations will be awarded a free registration for SFRR-E conference 2026 in Mainz! You have all the info in the SFRR-E intranet!
October 30, 2025 at 9:33 AM
🚨ECRs apply to the PhD Symposium! Best presentations will be awarded a free registration for SFRR-E conference 2026 in Mainz! You have all the info in the SFRR-E intranet!
Reposted by Vanesa Cepas López
New biosensor for REDOX lovers! Scientists at VIB, Daria Ezeriņa and Joris Messens, with global partners, developed HyPerFLEX🌈!
@messenslab.bsky.social
@messenslab.bsky.social
October 17, 2025 at 3:11 PM
New biosensor for REDOX lovers! Scientists at VIB, Daria Ezeriņa and Joris Messens, with global partners, developed HyPerFLEX🌈!
@messenslab.bsky.social
@messenslab.bsky.social
Reposted by Vanesa Cepas López
REVIEW🚨
The authors discuss the regulation and interplay of the metabolic #CellDeath pathways #ferroptosis, #disulfidptosis and #cuproptosis and explore how these mechanisms can be harnessed for cancer therapies.
@mdanderson.bsky.social
📖 ⬇️
https://bit.ly/3L3vN...
The authors discuss the regulation and interplay of the metabolic #CellDeath pathways #ferroptosis, #disulfidptosis and #cuproptosis and explore how these mechanisms can be harnessed for cancer therapies.
@mdanderson.bsky.social
📖 ⬇️
https://bit.ly/3L3vN...
October 22, 2025 at 2:46 PM
REVIEW🚨
The authors discuss the regulation and interplay of the metabolic #CellDeath pathways #ferroptosis, #disulfidptosis and #cuproptosis and explore how these mechanisms can be harnessed for cancer therapies.
@mdanderson.bsky.social
📖 ⬇️
https://bit.ly/3L3vN...
The authors discuss the regulation and interplay of the metabolic #CellDeath pathways #ferroptosis, #disulfidptosis and #cuproptosis and explore how these mechanisms can be harnessed for cancer therapies.
@mdanderson.bsky.social
📖 ⬇️
https://bit.ly/3L3vN...
Reposted by Vanesa Cepas López
🚨New paper published today on cancer bugs and drugs!🚨
“Chemotherapy modulation by a cancer-associated microbiota metabolite”
Congrats to the Cabreiro lab on this exciting study!
#Cancer #Microbiome #Metabolism #Chemotherapy
#MRC_LMS #ImperialCollege #CECAD_Cologne
www.cell.com/cell-systems...
“Chemotherapy modulation by a cancer-associated microbiota metabolite”
Congrats to the Cabreiro lab on this exciting study!
#Cancer #Microbiome #Metabolism #Chemotherapy
#MRC_LMS #ImperialCollege #CECAD_Cologne
www.cell.com/cell-systems...
September 10, 2025 at 5:16 PM
🚨New paper published today on cancer bugs and drugs!🚨
“Chemotherapy modulation by a cancer-associated microbiota metabolite”
Congrats to the Cabreiro lab on this exciting study!
#Cancer #Microbiome #Metabolism #Chemotherapy
#MRC_LMS #ImperialCollege #CECAD_Cologne
www.cell.com/cell-systems...
“Chemotherapy modulation by a cancer-associated microbiota metabolite”
Congrats to the Cabreiro lab on this exciting study!
#Cancer #Microbiome #Metabolism #Chemotherapy
#MRC_LMS #ImperialCollege #CECAD_Cologne
www.cell.com/cell-systems...
The @sfrre-ecr.bsky.social webinar series is back! You can't miss tomorrow's talks by @avdar66.bsky.social and Thibaut Vignane for some exciting insights about Redox Regulation in Cellular Aggregates 🚀
🎬 WE’RE BACK with the 4th round of ECR webinars! 🚀
Join us tomorrow, September 2nd for our season opener:
"Redox regulation in cellular aggregates"
🎤 Speakers: Avilien Dard, PhD & Thibaut Vignane, PhD
#SFRRIWebinars #ECRVoices #RedoxResearch #WeAreSFRR #ScienceCommunity #LifelongLearning
Join us tomorrow, September 2nd for our season opener:
"Redox regulation in cellular aggregates"
🎤 Speakers: Avilien Dard, PhD & Thibaut Vignane, PhD
#SFRRIWebinars #ECRVoices #RedoxResearch #WeAreSFRR #ScienceCommunity #LifelongLearning
September 1, 2025 at 12:34 PM
The @sfrre-ecr.bsky.social webinar series is back! You can't miss tomorrow's talks by @avdar66.bsky.social and Thibaut Vignane for some exciting insights about Redox Regulation in Cellular Aggregates 🚀
Reposted by Vanesa Cepas López
🚀New preprint w/ @roberto_amv: We used chemogenetics to precisely control mitochondrial H2O2 in skeletal muscle in vivo. This exposes a dose-dependent sequence: translation suppression → proteolysis → denervation-like → degeneration @tejensen23 www.biorxiv.org/content/10.1...
August 28, 2025 at 2:13 PM
🚀New preprint w/ @roberto_amv: We used chemogenetics to precisely control mitochondrial H2O2 in skeletal muscle in vivo. This exposes a dose-dependent sequence: translation suppression → proteolysis → denervation-like → degeneration @tejensen23 www.biorxiv.org/content/10.1...
Reposted by Vanesa Cepas López
🍹Interested in #DevBio and #metabolism ? This Review discusses the relationship between metabolism and embryogenesis!
👉https://rdcu.be/eCHvJ
bit.ly/4oVnB4t
👉https://rdcu.be/eCHvJ
bit.ly/4oVnB4t
Metabolic regulation of key developmental events during mammalian embryogenesis - Nature Cell Biology
This Review discusses the intricate relationship between metabolism and embryogenesis, highlighting the orchestration of key developmental processes by metabolites and signalling molecules that provid...
bit.ly
August 27, 2025 at 1:15 PM
🍹Interested in #DevBio and #metabolism ? This Review discusses the relationship between metabolism and embryogenesis!
👉https://rdcu.be/eCHvJ
bit.ly/4oVnB4t
👉https://rdcu.be/eCHvJ
bit.ly/4oVnB4t
Reposted by Vanesa Cepas López
I am very happy to share that my PhD work in the Mansfeld lab (www.mansfeldlab.com) was published yesterday! 🎉 In this study, we characterized a novel redox switch on p21 that regulates proliferation: www.cell.com/molecular-ce...
Huge thanks to everyone involved for making this possible 🙏@icr.ac.uk
Huge thanks to everyone involved for making this possible 🙏@icr.ac.uk
A redox switch in p21-CDK feedback during G2 phase controls the proliferation-cell cycle exit decision
ROS oxidize cell cycle proteins and regulate cell proliferation. Vorhauser et al.
show that oxidation of the cyclin-dependent kinase (CDK) inhibitor p21 at cysteine
41 (C41) during the G2 phase contro...
www.cell.com
August 26, 2025 at 7:18 AM
I am very happy to share that my PhD work in the Mansfeld lab (www.mansfeldlab.com) was published yesterday! 🎉 In this study, we characterized a novel redox switch on p21 that regulates proliferation: www.cell.com/molecular-ce...
Huge thanks to everyone involved for making this possible 🙏@icr.ac.uk
Huge thanks to everyone involved for making this possible 🙏@icr.ac.uk
If you’re looking for a wonderful postdoc experience plus exciting project, this is the place!
A new postdoc position in our group will open early next year — looking for candidates with a proven track record & relevant experience.
If #CRISPRscreens, #syntheticlethality, #smallmolecules & #celldeath excite you, let’s talk! DMs welcome.
pls share 🙏
If #CRISPRscreens, #syntheticlethality, #smallmolecules & #celldeath excite you, let’s talk! DMs welcome.
pls share 🙏
August 4, 2025 at 5:46 PM
If you’re looking for a wonderful postdoc experience plus exciting project, this is the place!
Reposted by Vanesa Cepas López
Save the dates!
July 8, 2025 at 5:57 PM
Save the dates!
Reposted by Vanesa Cepas López
Happy to share our review paper, "Emerging Trends for the Regulation of Thiol-Based RedoxTranscription Factor Pathways" doi.org/10.1021/acs.... It was fun learning about the really cool science being undertaken by some excellent labs. Thanks, ACS Biochemistry, for the invite.
Emerging Trends for the Regulation of Thiol-Based Redox Transcription Factor Pathways
Thiol-based redox transcription factor pathways play central roles in the cellular response to peroxide stress. We review the bacterial OxyR, yeast AP-1 and mammalian NRF2/Keap1 systems and the princi...
doi.org
June 30, 2025 at 9:54 AM
Happy to share our review paper, "Emerging Trends for the Regulation of Thiol-Based RedoxTranscription Factor Pathways" doi.org/10.1021/acs.... It was fun learning about the really cool science being undertaken by some excellent labs. Thanks, ACS Biochemistry, for the invite.
Reposted by Vanesa Cepas López
Don't miss it !
🧪 The 2nd FEBS Redox Medicine Workshop will explore how the exposome—diet, chemicals, microbes & more—modulates redox regulation in health & disease. From tools to therapies, talks span redox in metabolism, epigenetics, transcription, cell death & beyond.
#Redox #Exposome #FEBS
🧪 The 2nd FEBS Redox Medicine Workshop will explore how the exposome—diet, chemicals, microbes & more—modulates redox regulation in health & disease. From tools to therapies, talks span redox in metabolism, epigenetics, transcription, cell death & beyond.
#Redox #Exposome #FEBS
June 29, 2025 at 12:17 PM
Reposted by Vanesa Cepas López
🎉Excited to share our latest paper, published in Nature Communications!🎉
"Enhancing autophagy by redox regulation extends lifespan in Drosophila"
#redox #metabolism #ageing #Drosophila
@natcomms.nature.com @mrc-lms.bsky.social
doi.org/10.1038/s414...
"Enhancing autophagy by redox regulation extends lifespan in Drosophila"
#redox #metabolism #ageing #Drosophila
@natcomms.nature.com @mrc-lms.bsky.social
doi.org/10.1038/s414...
Enhancing autophagy by redox regulation extends lifespan in Drosophila - Nature Communications
Redox signalling is emerging as an important regulator of metabolism and physiology, which is dysregulated in ageing and disease. Here, the authors show that redox regulation of a key redox sensitive ...
doi.org
June 27, 2025 at 11:21 AM
🎉Excited to share our latest paper, published in Nature Communications!🎉
"Enhancing autophagy by redox regulation extends lifespan in Drosophila"
#redox #metabolism #ageing #Drosophila
@natcomms.nature.com @mrc-lms.bsky.social
doi.org/10.1038/s414...
"Enhancing autophagy by redox regulation extends lifespan in Drosophila"
#redox #metabolism #ageing #Drosophila
@natcomms.nature.com @mrc-lms.bsky.social
doi.org/10.1038/s414...
🎉 Exciting news! I’ve been awarded an ECR seed grant from SFRR-E! It supports early career researchers in launching new projects and generating preliminary data for future grant applications. Grateful for the support and looking forward to getting started!
🔗 www.sfrr-europe.org/index.php/aw...
🔗 www.sfrr-europe.org/index.php/aw...
ECR FELLOWSHIP AWARDEES
www.sfrr-europe.org
June 24, 2025 at 5:47 PM
🎉 Exciting news! I’ve been awarded an ECR seed grant from SFRR-E! It supports early career researchers in launching new projects and generating preliminary data for future grant applications. Grateful for the support and looking forward to getting started!
🔗 www.sfrr-europe.org/index.php/aw...
🔗 www.sfrr-europe.org/index.php/aw...
Reposted by Vanesa Cepas López
Organelle conversations drive ferroptosis -
news and views on a recent study by @mariamls.bsky.social and colleagues
www.nature.com/articles/s41...
news and views on a recent study by @mariamls.bsky.social and colleagues
www.nature.com/articles/s41...
Organelle conversations drive ferroptosis - Nature Cell Biology
Ferroptosis begins with phospholipid peroxidation, leading to membrane damage rupture and cell death. Although research has surged, the intracellular site for ferroptosis initiation remains uncertain....
www.nature.com
June 19, 2025 at 9:28 AM
Organelle conversations drive ferroptosis -
news and views on a recent study by @mariamls.bsky.social and colleagues
www.nature.com/articles/s41...
news and views on a recent study by @mariamls.bsky.social and colleagues
www.nature.com/articles/s41...
Reposted by Vanesa Cepas López
Want to apply for a Marie Skłodowska-Curie Fellowships to work with us? Apply: cimus.usc.gal/jobs/marie-s...
Marie Skłodowska-Curie Fellowships: Call for Expressions of Interest 2025 | CiMUS
Marie Skłodowska-Curie Fellowships: Call for Expressions of Interest 2025
cimus.usc.gal
June 4, 2025 at 10:08 PM
Want to apply for a Marie Skłodowska-Curie Fellowships to work with us? Apply: cimus.usc.gal/jobs/marie-s...
Reposted by Vanesa Cepas López
New review together with
@k-hadian.bsky.social group-
Have fun reading!
#ferroptosis #nutrition #celldeath
www.sciencedirect.com/science/arti...
@k-hadian.bsky.social group-
Have fun reading!
#ferroptosis #nutrition #celldeath
www.sciencedirect.com/science/arti...
The metabolic code of ferroptosis: nutritional regulators of cell death
Ferroptosis is a distinctive form of regulated cell death driven by iron-dependent phospholipid peroxidation. Its initiation and suppression are finel…
www.sciencedirect.com
May 29, 2025 at 6:16 AM
New review together with
@k-hadian.bsky.social group-
Have fun reading!
#ferroptosis #nutrition #celldeath
www.sciencedirect.com/science/arti...
@k-hadian.bsky.social group-
Have fun reading!
#ferroptosis #nutrition #celldeath
www.sciencedirect.com/science/arti...
Reposted by Vanesa Cepas López
.🧬We looked for a CD44:SLC1A2 fusion in breast cancer. The data said no. Instead of shelving it, we published.
📢 Now out in @SpringerNature MCB: link.springer.com/article/10.1...
Negative results matter. Transparency matters. Proud of this one 🥳! #OpenScience
📢 Now out in @SpringerNature MCB: link.springer.com/article/10.1...
Negative results matter. Transparency matters. Proud of this one 🥳! #OpenScience
CD44 and SLC1A2 are commonly regulated but do not form a fusion transcript in ER+ breast cancer - Molecular and Cellular Biochemistry
Endocrine therapy (ET) is essential for managing ER+ HER2− breast cancer; however, resistance remains a significant clinical challenge. This study investigated whether CD44-SLC1A2 gene fusions, report...
link.springer.com
May 24, 2025 at 9:21 AM
.🧬We looked for a CD44:SLC1A2 fusion in breast cancer. The data said no. Instead of shelving it, we published.
📢 Now out in @SpringerNature MCB: link.springer.com/article/10.1...
Negative results matter. Transparency matters. Proud of this one 🥳! #OpenScience
📢 Now out in @SpringerNature MCB: link.springer.com/article/10.1...
Negative results matter. Transparency matters. Proud of this one 🥳! #OpenScience
🚨🚨The call for the new edition of the Mentoring Program is open. You can apply as a mentor or mentee through the SFRR-E intranet, it only takes 10 minutes!
Say hello to Tim, Pariki, Timo, and Vanesa.
👥 Mentoring Program — Personalized mentor–mentee pairs to support your career journey.
📝 Editorial Mentoring Program — Learn how to peer-review scientific papers with guidance from senior researchers.
Interested? Contact us ecr@sfrr-europe.org
👥 Mentoring Program — Personalized mentor–mentee pairs to support your career journey.
📝 Editorial Mentoring Program — Learn how to peer-review scientific papers with guidance from senior researchers.
Interested? Contact us ecr@sfrr-europe.org
May 21, 2025 at 5:41 PM
🚨🚨The call for the new edition of the Mentoring Program is open. You can apply as a mentor or mentee through the SFRR-E intranet, it only takes 10 minutes!
Reposted by Vanesa Cepas López
The @EMBO workshop #EMBOthiolSwitches is coming up soon, join us in beautiful Sant Feliu de Guíxols, Spain, 13–18 September 2025!
We have a fantastic speaker lineup, with a few spots still open for short talks. Abstract deadline extended to 31 May 2025.
meetings.embo.org/event/25-thi...
We have a fantastic speaker lineup, with a few spots still open for short talks. Abstract deadline extended to 31 May 2025.
meetings.embo.org/event/25-thi...
Thiol-based redox switches: From chemistry to physiology and pathology
Redox reactions have been essential for the emergence of life on Earth, and diverse strategies have evolved for responding to various cellular redox species. These mechanisms are still of vital impor…
meetings.embo.org
May 19, 2025 at 6:45 AM
The @EMBO workshop #EMBOthiolSwitches is coming up soon, join us in beautiful Sant Feliu de Guíxols, Spain, 13–18 September 2025!
We have a fantastic speaker lineup, with a few spots still open for short talks. Abstract deadline extended to 31 May 2025.
meetings.embo.org/event/25-thi...
We have a fantastic speaker lineup, with a few spots still open for short talks. Abstract deadline extended to 31 May 2025.
meetings.embo.org/event/25-thi...
Reposted by Vanesa Cepas López
New Professor position at Saarland University for Cell Physiology!
We are looking for a new colleague in the biology department at Saarland University!
We are looking for excellent Cell Biologists / Cell Physiologists for a W2 tenure track W3 professorship in 'Dynamics of Biological Systems'.
Please share!
jobs.zeit.de/jobs/w2-prof...
We are looking for excellent Cell Biologists / Cell Physiologists for a W2 tenure track W3 professorship in 'Dynamics of Biological Systems'.
Please share!
jobs.zeit.de/jobs/w2-prof...
W2 Professorship (with tenure track to W3) in the Dynamics of Biological Systems (m/f/x) - Universität des Saarlandes
Universität des Saarlandes bietet Stelle als W2 Professorship (with tenure track to W3) in the Dynamics of Biological Systems (m/f/x) in Saarbrücken - jetzt bewerben!
jobs.zeit.de
May 12, 2025 at 3:01 PM
New Professor position at Saarland University for Cell Physiology!
Reposted by Vanesa Cepas López
A new tool from our lab :-). Together with the Brachvogel, Bogeski and Mielenz labs. We developed a genetically encoded sensor to monitor activity of the dipeptidases DPP8 and DPP9 in cells allowing us to ask fundamental questions about their spatiotemporal regulation. DOI: 10.26508/lsa.202403076
May 12, 2025 at 3:39 PM
A new tool from our lab :-). Together with the Brachvogel, Bogeski and Mielenz labs. We developed a genetically encoded sensor to monitor activity of the dipeptidases DPP8 and DPP9 in cells allowing us to ask fundamental questions about their spatiotemporal regulation. DOI: 10.26508/lsa.202403076
Reposted by Vanesa Cepas López
Excited to see our N&V w/ @mikelangelipid.bsky.social published in Nature, highlighting new work from Raphael Rodriguez and team. A heterofunctional molecule that activates lysosomal iron triggers lipid peroxidation and ferroptosis in therapy-resistant cancer cells. www.nature.com/articles/d41...
Lipid-degrading small molecule kills cancer cells by ferroptosis
A molecule designed to activate iron locked up in organelles called lysosomes and thereby induce cell death might offer a way to tackle treatment-resistant cancer.
www.nature.com
May 7, 2025 at 10:17 PM
Excited to see our N&V w/ @mikelangelipid.bsky.social published in Nature, highlighting new work from Raphael Rodriguez and team. A heterofunctional molecule that activates lysosomal iron triggers lipid peroxidation and ferroptosis in therapy-resistant cancer cells. www.nature.com/articles/d41...
Reposted by Vanesa Cepas López
Monitoring subcellular NADP redox state with NAPstar biosensors @riemerlab.bsky.social @morganlab-saarland.bsky.social
@jan-oleniemeier.bsky.social
www.sciencedirect.com/science/arti...
@jan-oleniemeier.bsky.social
www.sciencedirect.com/science/arti...
Monitoring subcellular NADP redox state with NAPstar biosensors
www.sciencedirect.com
April 17, 2025 at 6:58 AM
Monitoring subcellular NADP redox state with NAPstar biosensors @riemerlab.bsky.social @morganlab-saarland.bsky.social
@jan-oleniemeier.bsky.social
www.sciencedirect.com/science/arti...
@jan-oleniemeier.bsky.social
www.sciencedirect.com/science/arti...
📢 Exciting Webinar Alert!
Join us tomorrow, April 1st, at 15:00 CET for an unmissable webinar on chaperones in redox biology, hosted by @sfrre-ecr.bsky.social! We’re thrilled to welcome two fantastic speakers: @ulrichlab.bsky.social and @rsutandy.bsky.social.
See you there!
Join us tomorrow, April 1st, at 15:00 CET for an unmissable webinar on chaperones in redox biology, hosted by @sfrre-ecr.bsky.social! We’re thrilled to welcome two fantastic speakers: @ulrichlab.bsky.social and @rsutandy.bsky.social.
See you there!
March 31, 2025 at 11:27 AM
📢 Exciting Webinar Alert!
Join us tomorrow, April 1st, at 15:00 CET for an unmissable webinar on chaperones in redox biology, hosted by @sfrre-ecr.bsky.social! We’re thrilled to welcome two fantastic speakers: @ulrichlab.bsky.social and @rsutandy.bsky.social.
See you there!
Join us tomorrow, April 1st, at 15:00 CET for an unmissable webinar on chaperones in redox biology, hosted by @sfrre-ecr.bsky.social! We’re thrilled to welcome two fantastic speakers: @ulrichlab.bsky.social and @rsutandy.bsky.social.
See you there!