Cannabis and Cannabinoid Research
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Cannabis and Cannabinoid Research
@cannabisjrnl.bsky.social
Cannabis and Cannabinoid Research is the premier peer-reviewed journal dedicated to the scientific, medical, and psychosocial exploration of clinical cannabis, cannabinoids, and the endocannabinoid system.
🔥 New study: Nearly 1 in 3 Californians aged 50+ is a caregiver, & caregivers—especially those supporting someone with dementia—are more likely to use cannabis than non-caregivers. Call for more work on whether cannabis helps or harms caregiver well-being: doi.org/10.1177/2578...
Taking Care of Themselves: Cannabis Use Among Informal Care Partners of Older Adults | Cannabis and Cannabinoid Research
Background: Cannabis use among older persons has been increasing relative to younger populations, and persons over 50 years old are more likely to use cannabis for age-related therapeutic purposes.…
doi.org
December 8, 2025 at 1:01 PM
🧬 New study finds heavy cannabis use in women may be linked to MASLD with liver fibrosis, while overall cannabis use shows no effect on liver stiffness. Gender & frequency matter!
🔗 doi.org/10.1089/can....

#CannabisResearch #LiverHealth #MASLD #WomenHealth
Associations of Cannabis Use, Metabolic Dysfunction-Associated Steatotic Liver Disease, and Liver Fibrosis in U.S. Adults | Cannabis and Cannabinoid Research
Introduction: Following the introduction of metabolic dysfunction-associated steatotic liver disease (MASLD) as a replacement term for nonalcoholic fatty liver disease, the relationship between MASLD…
doi.org
December 1, 2025 at 1:03 PM
🌿 New study: Chronic cannabis users hospitalized with COVID-19 had lower rates of severe infection, intubation, ARDS, and mortality compared with non-users—potentially linked to immunomodulatory effects.
🔗 doi.org/10.1089/can....

#CannabisResearch #COVID19 #Immunology #PublicHealth
November 26, 2025 at 1:02 PM
🌿 New randomized trial: Chronic CBD reduced daytime sleepiness, fatigue, and improved psychological well-being in patients with hypertension—even without changing sleep quality.
🔗 doi.org/10.1089/can....

#CBD #Hypertension #Sleepiness #CannabisResearch
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doi.org
November 26, 2025 at 1:00 PM
🧬 New study finds cell-type specific regulation of the endocannabinoid system in the endometrium, with higher FAAH in epithelial cells and changes across the menstrual cycle—offering insights into reproductive biology.
🔗 doi.org/10.1089/can....

#Endocannabinoids #Endometriosis
November 24, 2025 at 1:01 PM
🌿 New study: CBD-rich cannabis treatment in autistic children may reduce anxiety (general, social, panic, separation) and decrease repetitive behaviors.
🔗 doi.org/10.1089/can....

#AutismResearch #CBD #CannabisTherapy #ChildHealth
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doi.org
November 19, 2025 at 1:02 PM
� New study shows CBD—but not THC—boosts anti-inflammatory eicosanoids in plasma, highlighting its potential as a therapy for inflammatory diseases.
#CannabisResearch #CBD #Inflammation #Therapeutics

Read: www.liebertpub.com/doi/10.1089/...
November 17, 2025 at 1:01 PM
🚨 New review shows 1 in 3 children on therapeutic cannabinoids experience gastrointestinal side effects, especially those with Dravet syndrome. Monitoring & education are key!
🔗 doi.org/10.1089/can....

#CannabisResearch #Pediatrics #Epilepsy
Prevalence of Gastrointestinal Adverse Events of Therapeutic Cannabinoids in Children: A Systematic Review and Meta-Analysis | Cannabis and Cannabinoid Research
Introduction: The endocannabinoid system plays a crucial role in gastrointestinal homeostasis; although some gastrointestinal adverse events have been reported with therapeutic cannabinoids in…
doi.org
November 12, 2025 at 1:02 PM
🔥 Most-Read in 2025 (so far): From chemovar classification and THC/CBD pharmacology to clinical and product studies — here are the Top 10 most-requested papers from Cannabis and Cannabinoid Research!

🌿 📖 home.liebertpub.com/publications...
November 10, 2025 at 1:01 PM
🌿 Cannabis and Cannabinoid Research celebrates 10 years by highlighting the Top 10 most-downloaded articles of all time!

From opioid substitution to CBD safety, immune function, and pain management—these papers shaped a decade of cannabis science.
📖 Explore more: home.liebertpub.com/publications...
November 5, 2025 at 1:01 PM
🎉 Cannabis and Cannabinoid Research turns 10!
We’re celebrating by featuring the most-downloaded studies from the past decade and from 2025—research that’s shaped how we understand cannabis, cannabinoids, and health.

Stay tuned for our highlights!
#CannabisResearch #Cannabinoids #10YearsOfCCR
November 3, 2025 at 1:01 PM
🌿 Study: Among adults with cannabis use disorder, 89% used ≥1 other substance, 34% used 2+. Mood & personality disorders were linked to higher polysubstance use. Screening recommended.

Read more: doi.org/10.1177/2578...

#CannabisResearch #CUD #PolysubstanceUse #MentalHealth
doi.org
October 29, 2025 at 12:03 PM
💚 Study: In adults without preexisting CKD, regular cannabis use was not linked to higher risk of chronic kidney disease, rapid kidney decline, or albuminuria.

Read more: doi.org/10.1177/2578...

#CannabisResearch #KidneyHealth #LongitudinalStudy
doi.org
October 27, 2025 at 12:03 PM
🌿 Study: Cannabis purchasing decisions vary by user type. Retail employees care less about THC, more about brand & appearance. Frequent users value strain, production method, price & appearance.

Read more: doi.org/10.1177/2578...

#CannabisResearch #ConsumerBehavior #THC #CannabisPolicy
doi.org
October 22, 2025 at 12:08 PM
🚦 Study: Recreational cannabis legalization & dispensary openings in CT did not significantly change motor vehicle accident rates.

Read more: doi.org/10.1177/2578...

#CannabisResearch #RoadSafety #CannabisLegalization
doi.org
October 20, 2025 at 12:02 PM
🌿 Cannabis affects the brain differently across the lifespan:
-In utero & teens: High neurodevelopmental risk
-Late adulthood: Rising use, low perceived risk
-Policy, education, & research needed to reduce harm.
Read more: doi.org/10.1177/2578...
#CannabisResearch #THC #BrainHealth #Neurodevelopment
Age-Related Effects of Cannabis and Cannabinoids on Brain and Behavior | Cannabis and Cannabinoid Research
Introduction: The effect of cannabis use on health is likely to depend on individual differences. In particular, there is a growing need to understand the impact of cannabis and…
doi.org
October 15, 2025 at 12:03 PM
🌿 Pilot trial: Oral CBD ± THC reduced specific eCBome mediators (2-EPG & 2-OG) in people with HIV on ART. No major gut microbiome changes observed. Larger studies needed.

Read more: doi.org/10.1177/2578...

#CannabisResearch #CBD #THC #HIV #EndocannabinoidSystem #GutMicrobiome
doi.org
October 13, 2025 at 12:03 PM
🌿 New study: PEG carrier oil ↑ plasma THC vs PG/VG. Adolescents less sensitive to locomotor suppression, females metabolize THC slower. High-dose vaporized cannabis → hypothermia & antinociception in mice.

Read more: doi.org/10.1177/2578...

#CannabisResearch #THC #VaporizedCannabis #Neuroscience
October 8, 2025 at 12:03 PM
🌿 New review: Pure CBD may help social & generalized anxiety; Δ9-THC may reduce PTSD nightmares & tics in Tourette syndrome. Mixed formulations show no clear effect. More high-quality trials needed.

Read more: doi.org/10.1177/2578...

#CannabisResearch #CBD #THC #Anxiety #Tourette
Effects of Different Cannabinoid Formulations on Anxiety-Related Disorders, and Tourette Syndrome: A Systematic Review and Meta-Analysis | Cannabis and Cannabinoid Research
Introduction: Cannabinoid formulations have been increasingly proposed as therapeutic potential options for anxiety disorders (ADs). Several countries have expanded regulatory frameworks facilitating…
doi.org
October 6, 2025 at 12:02 PM
🧪 Study published in Cannabis and Cannabinoid Resarch finds Cannabigerol (CBG) safe and non-toxic in animal models, with lifespan extension benefits in worms.

Supports CBG’s potential as a safe therapeutic compound.
www.liebertpub.com/doi/10.1089/...
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www.liebertpub.com
September 24, 2025 at 12:28 PM
🧠 Study published in Cannabis and Cannabinoid Research suggests THCV may improve sustained attention and is well tolerated in healthy adults.

Promising early evidence for therapeutic uses in attention disorders.
www.liebertpub.com/doi/10.1089/...
A Two-Phase, Dose-Ranging, Placebo-Controlled Study of the Safety and Preliminary Test of Acute Effects of Oral Δ8-Tetrahydrocannabivarin in Healthy Participants | Cannabis and Cannabinoid Research
Introduction: Tetrahydrocannabivarin (THCV) is an understudied cannabinoid that appears to have effects that vary as a function of dose. No human study has evaluated the safety and nature of effects…
www.liebertpub.com
September 22, 2025 at 12:01 PM
📈 Cannabis use is up among older adults, raising health concerns. Age matters in cannabis effects—new study highlights need for targeted public health efforts.

More here:https://www.liebertpub.com/doi/10.1177/25785125251361926
Age Differences in Cannabis Consumption Patterns and in Associations Between Delta-9-Tetrahydrocannabinol Intake and Cannabis Use Disorders Among Adults with Daily Use | Cannabis and Cannabinoid Research
Introduction: Cannabis use has risen disproportionately among middle-aged and older U.S. adults, groups particularly vulnerable to adverse effects, including cannabis use disorder (CUD). Consumption…
www.liebertpub.com
September 17, 2025 at 12:03 PM
🔬 Study: Δ10-THC Isomers
A 2023 study in Cannabis and Cannabinoid Research shows both cis- and trans-Δ10-THC act as CB1 receptor antagonists, offering new insight into cannabinoid pharmacology and potential therapies.
👉 www.liebertpub.com/doi/10.1089/...
September 15, 2025 at 12:01 PM
📢 New meta-analysis: 1 in 3 pediatric patients on therapeutic cannabinoids experience GI side effects, with higher rates in interventional studies (47%). Important for clinicians & families to consider! 🩺

🌿https://www.liebertpub.com/doi/10.1089/can.2024.0104

#Cannabinoids
www.liebertpub.com
September 11, 2025 at 10:13 PM
** New study
Most adults with cannabis use disorder also struggle with additional substance use disorders—alcohol, opioids, stimulants, sedatives—highlighting the need for broader treatment approaches.

🔗 Read the full study: www.liebertpub.com/doi/10.1177/...

#PolysubstanceUse #CUD #MentalHealth
September 10, 2025 at 12:04 PM