C. Andrew Frank
@candrewfrank.bsky.social
Husband, dad to 3, son, brother, uncle, cousin, nephew. Fruit fly neuroscientist, geneticist. Professor, University of Iowa. He/him.
A red sky on Bluesky
November 12, 2025 at 3:21 AM
A red sky on Bluesky
Two Graeme Davis UCSF alums publishing in @plosbiology.org in consecutive weeks. Congratulations on this fantastic work, Kira!! 🎉
Congrats to Charlotte Taylor and team for dissecting how astrocyte networks integrate histamine to modulate adenosine over sleep and wake in unexpected ways:
dx.plos.org/10.1371/jour...
@vincenttse.bsky.social @maxine.science @trishavv.bsky.social
dx.plos.org/10.1371/jour...
@vincenttse.bsky.social @maxine.science @trishavv.bsky.social
Cortical astrocyte histamine-1-receptors regulate intracellular calcium and extracellular adenosine dynamics across sleep and wake
While histamine-1-receptor (H1R) signaling in neurons regulates arousal, these receptors are also abundant on cortical astrocytes. This study shows that astrocytic H1R signaling modulates calcium acti...
dx.plos.org
October 3, 2025 at 2:06 AM
Two Graeme Davis UCSF alums publishing in @plosbiology.org in consecutive weeks. Congratulations on this fantastic work, Kira!! 🎉
This is wild – an AI-generated, podcast-style bit about our recent @plosbiology.org paper produced by The Sanz Science Experience.
I listened. The clip was conversational, down-to-earth, and accurate. It was easy for me to understand, but the paper is from my lab.
www.youtube.com/watch?v=f--T...
I listened. The clip was conversational, down-to-earth, and accurate. It was easy for me to understand, but the paper is from my lab.
www.youtube.com/watch?v=f--T...
Mitochondrial Complex I, ROS and Homeostasis at the Synapse
YouTube video by The Sanz Science Experience
www.youtube.com
September 29, 2025 at 5:28 PM
This is wild – an AI-generated, podcast-style bit about our recent @plosbiology.org paper produced by The Sanz Science Experience.
I listened. The clip was conversational, down-to-earth, and accurate. It was easy for me to understand, but the paper is from my lab.
www.youtube.com/watch?v=f--T...
I listened. The clip was conversational, down-to-earth, and accurate. It was easy for me to understand, but the paper is from my lab.
www.youtube.com/watch?v=f--T...
We have an uncorrected proof published for Bhagaban Mallik's study on Mitochondrial Complex I and how it regulates synapse function. You can find it in @plosbiology.org. I am so proud!
H/T collaborators: Drs. Sajad Bhat and Xinnan Wang @xinnanwanglab.bsky.social
journals.plos.org/plosbiology/...
H/T collaborators: Drs. Sajad Bhat and Xinnan Wang @xinnanwanglab.bsky.social
journals.plos.org/plosbiology/...
Mitochondrial Complex I and ROS control neuromuscular function through opposing pre- and postsynaptic mechanisms
How do neurons adapt to mitochondrial dysfunction in different tissues? This study shows that Mitochondrial Complex I depletion triggers ROS-driven compensatory signaling in motor neurons that preserv...
journals.plos.org
September 22, 2025 at 10:53 PM
We have an uncorrected proof published for Bhagaban Mallik's study on Mitochondrial Complex I and how it regulates synapse function. You can find it in @plosbiology.org. I am so proud!
H/T collaborators: Drs. Sajad Bhat and Xinnan Wang @xinnanwanglab.bsky.social
journals.plos.org/plosbiology/...
H/T collaborators: Drs. Sajad Bhat and Xinnan Wang @xinnanwanglab.bsky.social
journals.plos.org/plosbiology/...
We have proofs! And you know what that means. Assertive editing.
A copy editor has flagged my name on an author line and wants me to spell out Carl Andrew Frank as my name instead of C. Andrew Frank.
I am irrationally irritated by this 😆
A copy editor has flagged my name on an author line and wants me to spell out Carl Andrew Frank as my name instead of C. Andrew Frank.
I am irrationally irritated by this 😆
September 19, 2025 at 7:42 PM
We have proofs! And you know what that means. Assertive editing.
A copy editor has flagged my name on an author line and wants me to spell out Carl Andrew Frank as my name instead of C. Andrew Frank.
I am irrationally irritated by this 😆
A copy editor has flagged my name on an author line and wants me to spell out Carl Andrew Frank as my name instead of C. Andrew Frank.
I am irrationally irritated by this 😆
I think that societal advancement requires nonviolence.
September 12, 2025 at 8:11 PM
I think that societal advancement requires nonviolence.
New email signature. I dropped the Associate. Now maybe I can drop the some of the pounds I gained as an Associate Professor😆
July 1, 2025 at 11:00 PM
New email signature. I dropped the Associate. Now maybe I can drop the some of the pounds I gained as an Associate Professor😆
Today I learned that you should not wash chicken.
June 9, 2025 at 4:06 PM
Today I learned that you should not wash chicken.
Grant reviewers are triaging Pope Francis’s tomb over font and kerning choices.
www.nytimes.com/2025/05/04/w...
www.nytimes.com/2025/05/04/w...
Designers Do a Double Take at the Lettering on Pope Francis’ Tombstone
Irregularly spaced letters spelling “F R A NCISC VS” have caused a stir among typography nerds who specialize in spacing and fonts. One called them “an abomination unto design.”
www.nytimes.com
May 4, 2025 at 7:25 PM
Grant reviewers are triaging Pope Francis’s tomb over font and kerning choices.
www.nytimes.com/2025/05/04/w...
www.nytimes.com/2025/05/04/w...
Drosophila neuroscience friends! Please help us to identify deserving Ph.D. students or recent Ph.D. graduates for the Elkins Memorial Lecture competition (CSHL, October 2025).
Details below – send nominations by email to Troy Littleton (troy@mit.edu).
Details below – send nominations by email to Troy Littleton (troy@mit.edu).
April 30, 2025 at 9:34 PM
Drosophila neuroscience friends! Please help us to identify deserving Ph.D. students or recent Ph.D. graduates for the Elkins Memorial Lecture competition (CSHL, October 2025).
Details below – send nominations by email to Troy Littleton (troy@mit.edu).
Details below – send nominations by email to Troy Littleton (troy@mit.edu).
Michelle Obama says she did not attend Donald Trump's second inauguration because she did not have anything to wear. Mad respect.
www.cbsnews.com/news/michell...
www.cbsnews.com/news/michell...
Michelle Obama addresses not attending Trump's inauguration, the importance of saying "no"
Former first lady Michelle Obama told actor Taraji P. Henson on her podcast, "IMO," about her choice to skip President Trump's inauguration.
www.cbsnews.com
April 24, 2025 at 9:40 PM
Michelle Obama says she did not attend Donald Trump's second inauguration because she did not have anything to wear. Mad respect.
www.cbsnews.com/news/michell...
www.cbsnews.com/news/michell...
Fenton 2011-2025
Frank family member 2015-2025
Who rescued whom? 💕 🐾
Frank family member 2015-2025
Who rescued whom? 💕 🐾
April 1, 2025 at 1:11 AM
Fenton 2011-2025
Frank family member 2015-2025
Who rescued whom? 💕 🐾
Frank family member 2015-2025
Who rescued whom? 💕 🐾
Standing up for Science in Iowa City
March 7, 2025 at 10:25 PM
Standing up for Science in Iowa City
Arial 11. Full justify with auto-hyphenation.
Figure legends: Arial 9. And brief because nobody wants to read them.
White space, yes. Walls of text, no.
Four figures because you ran out of time? No.
20 figures because you want to impress with a mountain of data? Also, no.
Figure legends: Arial 9. And brief because nobody wants to read them.
White space, yes. Walls of text, no.
Four figures because you ran out of time? No.
20 figures because you want to impress with a mountain of data? Also, no.
February 21, 2025 at 5:55 PM
Arial 11. Full justify with auto-hyphenation.
Figure legends: Arial 9. And brief because nobody wants to read them.
White space, yes. Walls of text, no.
Four figures because you ran out of time? No.
20 figures because you want to impress with a mountain of data? Also, no.
Figure legends: Arial 9. And brief because nobody wants to read them.
White space, yes. Walls of text, no.
Four figures because you ran out of time? No.
20 figures because you want to impress with a mountain of data? Also, no.
I wanted to share good news (which in normal times would be neutral). One of my lab's NIH grants was renewed for year 2 (March 1).
That means that funding is not completely frozen. And it means there are people in Bethesda who believe in the mission of the NIH and research. And I thank them.
That means that funding is not completely frozen. And it means there are people in Bethesda who believe in the mission of the NIH and research. And I thank them.
February 19, 2025 at 5:57 PM
I wanted to share good news (which in normal times would be neutral). One of my lab's NIH grants was renewed for year 2 (March 1).
That means that funding is not completely frozen. And it means there are people in Bethesda who believe in the mission of the NIH and research. And I thank them.
That means that funding is not completely frozen. And it means there are people in Bethesda who believe in the mission of the NIH and research. And I thank them.
If they cancel study section, can I get another dog? 🐕
January 24, 2025 at 12:50 AM
If they cancel study section, can I get another dog? 🐕
Hey Elon fans — your hero and his CEO are now trivializing the Holocaust with puns.
Some were curious or unsure about “the context” of his salute. Well…amidst all that talk he is adding his own context.
Some were curious or unsure about “the context” of his salute. Well…amidst all that talk he is adding his own context.
January 23, 2025 at 8:52 PM
Hey Elon fans — your hero and his CEO are now trivializing the Holocaust with puns.
Some were curious or unsure about “the context” of his salute. Well…amidst all that talk he is adding his own context.
Some were curious or unsure about “the context” of his salute. Well…amidst all that talk he is adding his own context.
Don’t dress like a doofus, friends! 🥶
January 21, 2025 at 2:27 PM
Don’t dress like a doofus, friends! 🥶
I am so proud of Dr. Bhagaban Mallik and the years of work he compiled to formulate this story. It has taken our group into new directions, and what more could you want out of science?
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Mitochondrial Complex I and ROS control synapse function through opposing pre- and postsynaptic mechanisms
Neurons require high amounts energy, and mitochondria help to fulfill this requirement. Dysfunctional mitochondria trigger problems in various neuronal tasks. Using the Drosophila neuromuscular juncti...
www.biorxiv.org
December 31, 2024 at 6:03 PM
I am so proud of Dr. Bhagaban Mallik and the years of work he compiled to formulate this story. It has taken our group into new directions, and what more could you want out of science?
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Folks who celebrated a CEO’s murder — and who now seem to be lionizing the killer as a combo hero/sex symbol — have bizarre moral compasses.
You can be dismayed by insurance practices AND oppose vigilante violence.
Oh, that anti-corporate hero? Undone by his visits to Starbucks and McDonald’s.
You can be dismayed by insurance practices AND oppose vigilante violence.
Oh, that anti-corporate hero? Undone by his visits to Starbucks and McDonald’s.
December 10, 2024 at 4:51 PM
Folks who celebrated a CEO’s murder — and who now seem to be lionizing the killer as a combo hero/sex symbol — have bizarre moral compasses.
You can be dismayed by insurance practices AND oppose vigilante violence.
Oh, that anti-corporate hero? Undone by his visits to Starbucks and McDonald’s.
You can be dismayed by insurance practices AND oppose vigilante violence.
Oh, that anti-corporate hero? Undone by his visits to Starbucks and McDonald’s.
Reposted by C. Andrew Frank
Score Update:
NYJ 26 - 32 MIA
Final
That's Scorigami!! It's the 1089th unique final score in NFL history.
NYJ 26 - 32 MIA
Final
That's Scorigami!! It's the 1089th unique final score in NFL history.
December 8, 2024 at 9:35 PM
Score Update:
NYJ 26 - 32 MIA
Final
That's Scorigami!! It's the 1089th unique final score in NFL history.
NYJ 26 - 32 MIA
Final
That's Scorigami!! It's the 1089th unique final score in NFL history.
We should all be fine with President Joe Biden's blanket pardon of Hunter Biden. After all, this is what the voters said they wanted in 2020, and a POTUS's pardon power is absolute.
That's how this works, right? I, for one, am glad that we can all play by the same rules.
That's how this works, right? I, for one, am glad that we can all play by the same rules.
December 2, 2024 at 9:19 PM
We should all be fine with President Joe Biden's blanket pardon of Hunter Biden. After all, this is what the voters said they wanted in 2020, and a POTUS's pardon power is absolute.
That's how this works, right? I, for one, am glad that we can all play by the same rules.
That's how this works, right? I, for one, am glad that we can all play by the same rules.