Cameron Myhrvold
cambearon.bsky.social
Cameron Myhrvold
@cambearon.bsky.social
Assistant Professor of Molecular Biology at Princeton, developing Cas13-based biotechnologies for studying RNA. Co-founder of Carver Biosciences.
My lab has developed mSHINE, allowing for both highly multiplexed and portable nucleic acid detection. Very exciting work led by the talented @sijbren-kramer.bsky.social, who is off to do a PhD at Stanford at the end of the month!
Multiplexed nucleic acid detection is critical for the surveillance of pathogens and mutations, but existing technologies either require extensive lab equipment or have low multiplexing. We built a portable microfluidic manifold for massively multiplexed CRISPR-based detection. (1/12)
A handheld microfluidic manifold for massively multiplexed CRISPR-based nucleic acid detection
Multiplexed methods for nucleic acid detection are immensely challenging to deploy outside of laboratory settings. Conversely, field-deployable methods are limited to low levels of multiplexing. Durin...
www.biorxiv.org
August 15, 2025 at 6:45 PM
Reposted by Cameron Myhrvold
Multiplexed nucleic acid detection is critical for the surveillance of pathogens and mutations, but existing technologies either require extensive lab equipment or have low multiplexing. We built a portable microfluidic manifold for massively multiplexed CRISPR-based detection. (1/12)
A handheld microfluidic manifold for massively multiplexed CRISPR-based nucleic acid detection
Multiplexed methods for nucleic acid detection are immensely challenging to deploy outside of laboratory settings. Conversely, field-deployable methods are limited to low levels of multiplexing. Durin...
www.biorxiv.org
August 15, 2025 at 6:34 PM
Our latest paper using SHINE for TB detection directly from sputum just came out in Science Advances! See the thread from co-first author Alex Bell for more details...
Despite antibiotic treatments, tuberculosis (TB) remains an enormous global health burden, in part driven by the difficulties in timely and accurate diagnosis. Can we use CRISPR to improve TB diagnosis to make it faster, simpler, and more accessible? (1/21)
August 7, 2025 at 4:10 PM