Buttitta Lab
@buttittalab.bsky.social
Studying cell cycle regulation during development at the University of Michigan. also at buttitta@drosophila.social
Reposted by Buttitta Lab
🧪🧪 Nobel laureate Hamilton Smith, who discovered molecular 'scissors' to cut DNA, dies at 94 -- Smith, a microbiologist whose discovery revolutionized the field of genetic engineering, was a Johns Hopkins School of Medicine alumnus and professor emeritus
hub.jhu.edu/2025/11/04/n...
hub.jhu.edu/2025/11/04/n...
Nobel laureate Hamilton Smith, who discovered molecular 'scissors' to cut DNA, dies at 94
Smith, a microbiologist whose discovery revolutionize the field of genetic engineering, was a Johns Hopkins School of Medicine alumnus and professor emeritus
hub.jhu.edu
November 11, 2025 at 7:55 PM
🧪🧪 Nobel laureate Hamilton Smith, who discovered molecular 'scissors' to cut DNA, dies at 94 -- Smith, a microbiologist whose discovery revolutionized the field of genetic engineering, was a Johns Hopkins School of Medicine alumnus and professor emeritus
hub.jhu.edu/2025/11/04/n...
hub.jhu.edu/2025/11/04/n...
Reposted by Buttitta Lab
Reposted by Buttitta Lab
The FlyBase situation has made the national news www.nbcnews.com/science/scie...
Trump's Harvard cuts threaten a giant in biomedical research: A database about the tiny fruit fly
This spring, the Trump administration rescinded a grant that maintained FlyBase, a pillar of global basic research, as part of its broader $2.2 billion funding cuts at Harvard.
www.nbcnews.com
September 16, 2025 at 1:08 PM
The FlyBase situation has made the national news www.nbcnews.com/science/scie...
Reposted by Buttitta Lab
New cell cycle meeting starts next summer!
events.faseb.org/event/c40174...
events.faseb.org/event/c40174...
Cell Cycle Regulation in Health and Disease.
Explore breakthroughs in cell cycle regulation and its impact on disease and therapies at this new multidisciplinary scientific meeting.
events.faseb.org
September 15, 2025 at 9:19 PM
New cell cycle meeting starts next summer!
events.faseb.org/event/c40174...
events.faseb.org/event/c40174...
Reposted by Buttitta Lab
Don't miss the next #SDBPostdocSeminar this Friday, September 12 at 3pm ET featuring @sarahcolijn.bsky.social from Washington University in St. Louis and @shyama13.bsky.social from the University of Pittsburgh. Register today and join us. bit.ly/4649fWS
September 9, 2025 at 9:42 PM
Don't miss the next #SDBPostdocSeminar this Friday, September 12 at 3pm ET featuring @sarahcolijn.bsky.social from Washington University in St. Louis and @shyama13.bsky.social from the University of Pittsburgh. Register today and join us. bit.ly/4649fWS
Reposted by Buttitta Lab
New in #GENETICS: From a genetic screen, Yi-Ting Huang and Brian Calvi identified the Src42A-Shark-Slpr pathway as an upstream regulator of JNK in induced endocycling cells in #Drosophila wing disc. buff.ly/wJmn8lp
September 3, 2025 at 8:03 PM
New in #GENETICS: From a genetic screen, Yi-Ting Huang and Brian Calvi identified the Src42A-Shark-Slpr pathway as an upstream regulator of JNK in induced endocycling cells in #Drosophila wing disc. buff.ly/wJmn8lp
Reposted by Buttitta Lab
'The ship is going down and we are powerless'- The Impact of Federal Funding Changes on Researchers Training the Next Generation of Scientists https://www.biorxiv.org/content/10.1101/2025.08.22.671828v1
August 28, 2025 at 5:03 AM
'The ship is going down and we are powerless'- The Impact of Federal Funding Changes on Researchers Training the Next Generation of Scientists https://www.biorxiv.org/content/10.1101/2025.08.22.671828v1
Thank you for featuring this work on #polyploidy and organ growth.
Adult growth in the Drosophila ejaculatory duct is driven by an evolutionarily conserved Juvenile Hormone–endocycle–protein synthesis axis essential for male fertility
by Navyashree Ramesh, Allison Box, Laura Buttitta
www.sciencedirect.com/science/arti...
#DBfeature #Drosophila #ReproductiveBiology
by Navyashree Ramesh, Allison Box, Laura Buttitta
www.sciencedirect.com/science/arti...
#DBfeature #Drosophila #ReproductiveBiology
August 17, 2025 at 2:19 AM
Thank you for featuring this work on #polyploidy and organ growth.
Reposted by Buttitta Lab
Highly frequent undesired insertional mutagenesis during Drosophila genome editing https://www.biorxiv.org/content/10.1101/2025.08.11.669658v1
August 12, 2025 at 4:17 AM
Highly frequent undesired insertional mutagenesis during Drosophila genome editing https://www.biorxiv.org/content/10.1101/2025.08.11.669658v1
This 👇🏻
FlyBase is that thing that weird little thing that props up all of modern health and genetics and ... oy
xkcd.com/2347/
xkcd.com/2347/
August 12, 2025 at 1:40 AM
This 👇🏻
Reposted by Buttitta Lab
Congrats to Kristen Verhey @kjverhey1.bsky.social, winner of
@ascbiology.bsky.social's Sandra Masur Senior Leadership Award. She combines remarkable scientific insight into molecular motors with leadership and mentoring in cell biology 🧪
www.ascb.org/society-news...
@ascbiology.bsky.social's Sandra Masur Senior Leadership Award. She combines remarkable scientific insight into molecular motors with leadership and mentoring in cell biology 🧪
www.ascb.org/society-news...
August 4, 2025 at 11:18 PM
Congrats to Kristen Verhey @kjverhey1.bsky.social, winner of
@ascbiology.bsky.social's Sandra Masur Senior Leadership Award. She combines remarkable scientific insight into molecular motors with leadership and mentoring in cell biology 🧪
www.ascb.org/society-news...
@ascbiology.bsky.social's Sandra Masur Senior Leadership Award. She combines remarkable scientific insight into molecular motors with leadership and mentoring in cell biology 🧪
www.ascb.org/society-news...
Reposted by Buttitta Lab
A window of cell cycle plasticity enables imperfect regeneration of an adult postmitotic organ in Drosophila https://www.biorxiv.org/content/10.1101/2025.06.05.658044v1
June 6, 2025 at 11:33 AM
A window of cell cycle plasticity enables imperfect regeneration of an adult postmitotic organ in Drosophila https://www.biorxiv.org/content/10.1101/2025.06.05.658044v1
Reposted by Buttitta Lab
Evidence for Transcriptomic Conservation Between the Main Cells of the Drosophila Prostate-Like Accessory Gland and Basal Cells of the Mammalian Prostate. https://www.biorxiv.org/content/10.1101/2025.06.05.658085v1
June 9, 2025 at 6:37 AM
Evidence for Transcriptomic Conservation Between the Main Cells of the Drosophila Prostate-Like Accessory Gland and Basal Cells of the Mammalian Prostate. https://www.biorxiv.org/content/10.1101/2025.06.05.658085v1
Reposted by Buttitta Lab
Thank you for the highlight of our work! #drosophila #cancer model.
Probing Prostate Cancer: Adult male fruit fly accessory gland-cancer as a model for studying human prostate cancer
Image made with @leicamicrosystems.bsky.social
microscopy
📷 S. Jaimian Church, @buttittalab.bsky.social et al
@umich.edu in @dmmjournal.bsky.social
➡️ bpod.org.uk/archive/2025...
Image made with @leicamicrosystems.bsky.social
microscopy
📷 S. Jaimian Church, @buttittalab.bsky.social et al
@umich.edu in @dmmjournal.bsky.social
➡️ bpod.org.uk/archive/2025...
June 5, 2025 at 10:37 PM
Thank you for the highlight of our work! #drosophila #cancer model.
Thank you for the highlight of our work! #drosophila #cancer model.
Probing Prostate Cancer: Adult male fruit fly accessory gland-cancer as a model for studying human prostate cancer
Image made with @leicamicrosystems.bsky.social
microscopy
📷 S. Jaimian Church, @buttittalab.bsky.social et al
@umich.edu in @dmmjournal.bsky.social
➡️ bpod.org.uk/archive/2025...
Image made with @leicamicrosystems.bsky.social
microscopy
📷 S. Jaimian Church, @buttittalab.bsky.social et al
@umich.edu in @dmmjournal.bsky.social
➡️ bpod.org.uk/archive/2025...
June 5, 2025 at 10:37 PM
Thank you for the highlight of our work! #drosophila #cancer model.
As a “fly person” even I have to admit this is pretty cool! 😎
This is how worm people cast their imaging molds. Consider me (i) jealous and (ii) full of questions #DevBio 🧪
June 1, 2025 at 12:54 PM
As a “fly person” even I have to admit this is pretty cool! 😎
Reposted by Buttitta Lab
Proposed cut to NSF Biology budget is 70%.
70%. Seventy.
Call your senators & reps nonstop. Give them numbers on NSF impact for state/district. tableau.external.nsf.gov/views/NSFbyN... explain this will decimate the economy if their districts, especially if it has a major research univ. 🧪
70%. Seventy.
Call your senators & reps nonstop. Give them numbers on NSF impact for state/district. tableau.external.nsf.gov/views/NSFbyN... explain this will decimate the economy if their districts, especially if it has a major research univ. 🧪
May 31, 2025 at 12:58 AM
Proposed cut to NSF Biology budget is 70%.
70%. Seventy.
Call your senators & reps nonstop. Give them numbers on NSF impact for state/district. tableau.external.nsf.gov/views/NSFbyN... explain this will decimate the economy if their districts, especially if it has a major research univ. 🧪
70%. Seventy.
Call your senators & reps nonstop. Give them numbers on NSF impact for state/district. tableau.external.nsf.gov/views/NSFbyN... explain this will decimate the economy if their districts, especially if it has a major research univ. 🧪
Pleased to share and amplify our most recent paper. Looking at #oncogene effects in the #drosophila #prostate which is #postmitotic and #polyploid. 🧪
The fruitfly prostate-like accessory gland is a postmitotic and polyploid tissue. S. Jaimian Church, @buttittalab.bsky.social & co show similarities between the oncogenic activity in the Drosophila accessory gland and in polyploid prostate cancer. doi.org/10.1242/dmm....
#prostatecancer #cancer
#prostatecancer #cancer
May 16, 2025 at 10:04 PM
Pleased to share and amplify our most recent paper. Looking at #oncogene effects in the #drosophila #prostate which is #postmitotic and #polyploid. 🧪
Reposted by Buttitta Lab
Love seeing the cancer cell biology collection @jcb.org! The image they went with for the cover is also pretty great 😜. rupress.org/collection/6...
Cancer Cell Biology 2025 | Rockefeller University Press
This collection comprises mechanisms underlying cancer cell invasion, including analyses of lipogenesis, lysosomal phosphoinositide homeostasis, and the la
rupress.org
April 23, 2025 at 3:42 PM
Love seeing the cancer cell biology collection @jcb.org! The image they went with for the cover is also pretty great 😜. rupress.org/collection/6...
Reposted by Buttitta Lab
If using Bloomigton #Drosophila Stock Center stocks, pls. acknowledge them & their NIH funding (P40 OD018537). Papers listing this no. are being harvested as evidence. We massively depend on the @bdsc.bsky.social & they need our support in these dire times! @flybase.bsky.social @fly-eds.bsky.social
April 10, 2025 at 6:06 AM
If using Bloomigton #Drosophila Stock Center stocks, pls. acknowledge them & their NIH funding (P40 OD018537). Papers listing this no. are being harvested as evidence. We massively depend on the @bdsc.bsky.social & they need our support in these dire times! @flybase.bsky.social @fly-eds.bsky.social
Reposted by Buttitta Lab
Published an op-ed for @cnn.com: “Nobel laureate: I owe America my success. Today, its scientific future is in danger.”
A personal reflection on what’s at stake as science funding gets slashed. I’d be grateful if you could amplify both in and beyond the science world.
www.cnn.com/2025/04/09/h...
A personal reflection on what’s at stake as science funding gets slashed. I’d be grateful if you could amplify both in and beyond the science world.
www.cnn.com/2025/04/09/h...
Nobel laureate: I owe America my success. Today, its scientific future is in danger | CNN
Dr. Ardem Patapoutian says he watches “with deep sadness as the United States’ remarkable scientific enterprise, which took generations of hard work and national investment to build, faces a concerted...
www.cnn.com
April 9, 2025 at 11:30 AM
Published an op-ed for @cnn.com: “Nobel laureate: I owe America my success. Today, its scientific future is in danger.”
A personal reflection on what’s at stake as science funding gets slashed. I’d be grateful if you could amplify both in and beyond the science world.
www.cnn.com/2025/04/09/h...
A personal reflection on what’s at stake as science funding gets slashed. I’d be grateful if you could amplify both in and beyond the science world.
www.cnn.com/2025/04/09/h...
Reposted by Buttitta Lab
Why Publish in Developmental Biology?
1/8
Reason #1 - DB is strongly committed to supporting trainees and junior scientists. Publish your first paper with us!
DB is the official journal of the SDB @socdevbio.bsky.social
Learn more here
elsevier.com/locate/ydbio
1/8
Reason #1 - DB is strongly committed to supporting trainees and junior scientists. Publish your first paper with us!
DB is the official journal of the SDB @socdevbio.bsky.social
Learn more here
elsevier.com/locate/ydbio
April 4, 2025 at 11:17 AM
Why Publish in Developmental Biology?
1/8
Reason #1 - DB is strongly committed to supporting trainees and junior scientists. Publish your first paper with us!
DB is the official journal of the SDB @socdevbio.bsky.social
Learn more here
elsevier.com/locate/ydbio
1/8
Reason #1 - DB is strongly committed to supporting trainees and junior scientists. Publish your first paper with us!
DB is the official journal of the SDB @socdevbio.bsky.social
Learn more here
elsevier.com/locate/ydbio
Reposted by Buttitta Lab
Developmental biology research leads to fundamental discoveries for biomedical research.
12/12
RNA Interference. Fire et al., 1998 PMID: 9486653
Worm image by Tokiko Furuta
@socdevbio.bsky.social
@rrbehringer.bsky.social
12/12
RNA Interference. Fire et al., 1998 PMID: 9486653
Worm image by Tokiko Furuta
@socdevbio.bsky.social
@rrbehringer.bsky.social
April 3, 2025 at 11:36 AM
Developmental biology research leads to fundamental discoveries for biomedical research.
12/12
RNA Interference. Fire et al., 1998 PMID: 9486653
Worm image by Tokiko Furuta
@socdevbio.bsky.social
@rrbehringer.bsky.social
12/12
RNA Interference. Fire et al., 1998 PMID: 9486653
Worm image by Tokiko Furuta
@socdevbio.bsky.social
@rrbehringer.bsky.social
Reposted by Buttitta Lab
Developmental biology research leads to fundamental discoveries for biomedical research.
5/12
In Situ Hybridization
Gall & Pardue, 1969. PMID: 4895535
Frog image by Brandy Walker (Rachel Miller Lab)
@socdevbio.bsky.social
@rrbehringer.bsky.social
5/12
In Situ Hybridization
Gall & Pardue, 1969. PMID: 4895535
Frog image by Brandy Walker (Rachel Miller Lab)
@socdevbio.bsky.social
@rrbehringer.bsky.social
March 25, 2025 at 11:36 AM
Developmental biology research leads to fundamental discoveries for biomedical research.
5/12
In Situ Hybridization
Gall & Pardue, 1969. PMID: 4895535
Frog image by Brandy Walker (Rachel Miller Lab)
@socdevbio.bsky.social
@rrbehringer.bsky.social
5/12
In Situ Hybridization
Gall & Pardue, 1969. PMID: 4895535
Frog image by Brandy Walker (Rachel Miller Lab)
@socdevbio.bsky.social
@rrbehringer.bsky.social