BioLamina
@biolaminaab.bsky.social
#StemCells and beyond! The world’s only manufacturer of full-length human recombinant laminins, Biolaminin®. We support scientists in advancing reproducible discoveries—from bench to clinic.
A research team discovered a beneficial subtype of macrophages that are drastically exhausted in an atopic dermatitis mouse model and restored these cells by reinforcing a natural cue from fibroblasts: full-length laminin proteins.
Read more in Cell. Mol. Life Sci: link.springer.com/article/10.1...
Read more in Cell. Mol. Life Sci: link.springer.com/article/10.1...
January 22, 2025 at 5:04 PM
A research team discovered a beneficial subtype of macrophages that are drastically exhausted in an atopic dermatitis mouse model and restored these cells by reinforcing a natural cue from fibroblasts: full-length laminin proteins.
Read more in Cell. Mol. Life Sci: link.springer.com/article/10.1...
Read more in Cell. Mol. Life Sci: link.springer.com/article/10.1...
Have you already read about the ALPA #cloning system?
Arrayed #CRISPR libraries w/ quadruple-gRNAs enhance gene perturbation efficiency and enable previously inaccessible screens.
#Gene knockout and ablation efficiencies were studied in #iPSCs and #kidney organoids.
www.nature.com/articles/s41...
Arrayed #CRISPR libraries w/ quadruple-gRNAs enhance gene perturbation efficiency and enable previously inaccessible screens.
#Gene knockout and ablation efficiencies were studied in #iPSCs and #kidney organoids.
www.nature.com/articles/s41...
Arrayed CRISPR libraries for the genome-wide activation, deletion and silencing of human protein-coding genes - Nature Biomedical Engineering
Arrayed CRISPR libraries with each plasmid encoding an array of four non-overlapping single-guide RNAs allow for the efficient genome-wide ablation, activation and epigenetic silencing of human protei...
www.nature.com
December 13, 2024 at 12:55 PM
#MSCs from #StemCells and osteoblastic differentiation—challenging!
At least the matrix of choice is easy: after extensive comparisons, Tian et al. conclude #LN521 performs the best. Consistently high
- proliferation
- MSC marker expression
- osteogenic differentiation
pubs.rsc.org/en/content/a...
At least the matrix of choice is easy: after extensive comparisons, Tian et al. conclude #LN521 performs the best. Consistently high
- proliferation
- MSC marker expression
- osteogenic differentiation
pubs.rsc.org/en/content/a...
Effect of extracellular matrix proteins on the differentiation of human pluripotent stem cells into mesenchymal stem cells
The transplantation of human mesenchymal stem cells (hMSCs), such as bone marrow stem cells (BMSCs) and adipose-derived stem cells (ADSCs), has shown beneficial effects in protecting transplanted tiss...
pubs.rsc.org
December 2, 2024 at 12:40 PM
#MSCs from #StemCells and osteoblastic differentiation—challenging!
At least the matrix of choice is easy: after extensive comparisons, Tian et al. conclude #LN521 performs the best. Consistently high
- proliferation
- MSC marker expression
- osteogenic differentiation
pubs.rsc.org/en/content/a...
At least the matrix of choice is easy: after extensive comparisons, Tian et al. conclude #LN521 performs the best. Consistently high
- proliferation
- MSC marker expression
- osteogenic differentiation
pubs.rsc.org/en/content/a...
Why not learn about #laminins and #cancer for a few minutes?
These basement membrane proteins influence how #cells sense ECM stiffness, affecting whether malignant cells breach barriers—a key step in #metastasis.
Read more on the recent review: www.sciencedirect.com/science/arti...
Redirecting
doi.org
November 29, 2024 at 6:51 PM
Why not learn about #laminins and #cancer for a few minutes?
These basement membrane proteins influence how #cells sense ECM stiffness, affecting whether malignant cells breach barriers—a key step in #metastasis.
Read more on the recent review: www.sciencedirect.com/science/arti...
How do you keep your stem cells genomically stable?
1q gain is a frequent aberration and is linked to culture conditions.
N. Krivec et al. showed that 1q-gained hPSCs can also take over during differentiation resulting in more immature cells.
Read more: doi.org/10.1038/s414...
#StemCell
1q gain is a frequent aberration and is linked to culture conditions.
N. Krivec et al. showed that 1q-gained hPSCs can also take over during differentiation resulting in more immature cells.
Read more: doi.org/10.1038/s414...
#StemCell
Gain of 1q confers an MDM4-driven growth advantage to undifferentiated and differentiating hESC while altering their differentiation capacity - Cell Death & Disease
Cell Death & Disease - Gain of 1q confers an MDM4-driven growth advantage to undifferentiated and differentiating hESC while altering their differentiation capacity
doi.org
November 25, 2024 at 8:54 AM
How do you keep your stem cells genomically stable?
1q gain is a frequent aberration and is linked to culture conditions.
N. Krivec et al. showed that 1q-gained hPSCs can also take over during differentiation resulting in more immature cells.
Read more: doi.org/10.1038/s414...
#StemCell
1q gain is a frequent aberration and is linked to culture conditions.
N. Krivec et al. showed that 1q-gained hPSCs can also take over during differentiation resulting in more immature cells.
Read more: doi.org/10.1038/s414...
#StemCell
We're looking forward to sharing, learning, and working together here!
We'd like to invite you to our webinar. Experts will discuss the latest advancements in #PSC therapy, sharing insights into how it is already transforming vision restoration, and what lies ahead ⏬
tinyurl.com/ajrh3k64
#stemcell
We'd like to invite you to our webinar. Experts will discuss the latest advancements in #PSC therapy, sharing insights into how it is already transforming vision restoration, and what lies ahead ⏬
tinyurl.com/ajrh3k64
#stemcell
November 21, 2024 at 1:36 PM
We're looking forward to sharing, learning, and working together here!
We'd like to invite you to our webinar. Experts will discuss the latest advancements in #PSC therapy, sharing insights into how it is already transforming vision restoration, and what lies ahead ⏬
tinyurl.com/ajrh3k64
#stemcell
We'd like to invite you to our webinar. Experts will discuss the latest advancements in #PSC therapy, sharing insights into how it is already transforming vision restoration, and what lies ahead ⏬
tinyurl.com/ajrh3k64
#stemcell