Andreas Beyer Group
@beyerlab.bsky.social
We use computers to understand biology.
Reposted by Andreas Beyer Group
How Leucine boosts energy production! 🚀
A research team around Professor Dr Thorsten Hoppe at @cecad.bsky.social has discovered how the amino acid Leucine from food increases cell energy and opens up new possibilities for treating metabolic diseases. 🌟
Read more 👇
uni.koeln/XMMXS
A research team around Professor Dr Thorsten Hoppe at @cecad.bsky.social has discovered how the amino acid Leucine from food increases cell energy and opens up new possibilities for treating metabolic diseases. 🌟
Read more 👇
uni.koeln/XMMXS
From food to fuel: How leucine enhances mitochondrial energy production
Researchers from the University of Cologne discovered how a specific dietary amino acid increases cellular energy, opening new possibilities for treating metabolic diseases
uni.koeln
October 31, 2025 at 1:33 PM
How Leucine boosts energy production! 🚀
A research team around Professor Dr Thorsten Hoppe at @cecad.bsky.social has discovered how the amino acid Leucine from food increases cell energy and opens up new possibilities for treating metabolic diseases. 🌟
Read more 👇
uni.koeln/XMMXS
A research team around Professor Dr Thorsten Hoppe at @cecad.bsky.social has discovered how the amino acid Leucine from food increases cell energy and opens up new possibilities for treating metabolic diseases. 🌟
Read more 👇
uni.koeln/XMMXS
Reposted by Andreas Beyer Group
🎤 Science gets loud!
Our #CRC1678 postdoc @nishahemandhar.bsky.social hits the stage at the Medical Faculty’s Science Slam!
🗓️ Nov 12, 6:30 PM
📍 Gebäude 9, Cologne
Join for a night of fast, fun, fascinating research!
🎟️ Info + Tickets: medfak.uni-koeln.de/en/fakultaet...
Our #CRC1678 postdoc @nishahemandhar.bsky.social hits the stage at the Medical Faculty’s Science Slam!
🗓️ Nov 12, 6:30 PM
📍 Gebäude 9, Cologne
Join for a night of fast, fun, fascinating research!
🎟️ Info + Tickets: medfak.uni-koeln.de/en/fakultaet...
Science Slam 2025
medfak.uni-koeln.de
October 31, 2025 at 2:25 PM
🎤 Science gets loud!
Our #CRC1678 postdoc @nishahemandhar.bsky.social hits the stage at the Medical Faculty’s Science Slam!
🗓️ Nov 12, 6:30 PM
📍 Gebäude 9, Cologne
Join for a night of fast, fun, fascinating research!
🎟️ Info + Tickets: medfak.uni-koeln.de/en/fakultaet...
Our #CRC1678 postdoc @nishahemandhar.bsky.social hits the stage at the Medical Faculty’s Science Slam!
🗓️ Nov 12, 6:30 PM
📍 Gebäude 9, Cologne
Join for a night of fast, fun, fascinating research!
🎟️ Info + Tickets: medfak.uni-koeln.de/en/fakultaet...
Reposted by Andreas Beyer Group
📢 We are thrilled that our Research Unit #FOR5762 is hosting this joint seminar with #CRC1678!
Don't miss Prof. Bernd Bukau's talk about 'Mechanisms of Co-Translational Folding and Assembly of Proteins' !
Don't miss Prof. Bernd Bukau's talk about 'Mechanisms of Co-Translational Folding and Assembly of Proteins' !
🚨 Speaker Alert! 🚨
We’re excited to welcome Prof. Bernd Bukau (ZMBH Heidelberg) for the next #CRC1678 Seminar!
🧬 Talking About Mechanisms of Co-Translational Folding and Assembly of Proteins
📅 October 23
📍 Auditorium, MPI for Biology of Ageing
⏰ 2:00 PM
Join us!
We’re excited to welcome Prof. Bernd Bukau (ZMBH Heidelberg) for the next #CRC1678 Seminar!
🧬 Talking About Mechanisms of Co-Translational Folding and Assembly of Proteins
📅 October 23
📍 Auditorium, MPI for Biology of Ageing
⏰ 2:00 PM
Join us!
October 20, 2025 at 8:51 AM
Reposted by Andreas Beyer Group
PhD studentship available in our lab to study ageing, longevity and cellular rejuvenation using computational methods and machine learning/AI.
Applications are open to UK and international students.
Deadline: 27 November 2025.
www.findaphd.com/phds/project...
Applications are open to UK and international students.
Deadline: 27 November 2025.
www.findaphd.com/phds/project...
Developing and applying computational methods to study ageing and cellular rejuvenation at University of Birmingham on FindAPhD.com
PhD Project - Developing and applying computational methods to study ageing and cellular rejuvenation at University of Birmingham, listed on FindAPhD.com
www.findaphd.com
October 19, 2025 at 7:00 PM
PhD studentship available in our lab to study ageing, longevity and cellular rejuvenation using computational methods and machine learning/AI.
Applications are open to UK and international students.
Deadline: 27 November 2025.
www.findaphd.com/phds/project...
Applications are open to UK and international students.
Deadline: 27 November 2025.
www.findaphd.com/phds/project...
Reposted by Andreas Beyer Group
Don't miss our cool event in Cologne @mpiage.bsky.social on 14 November!
We would like to invite all Rhineland RNA enthusiasts to attend our next series of in-person talks, featuring local and invited speakers. Highlights include the external talks by Didier Stainier, Simon Bekker-Jensen and Ranen Aviner. Please, register: tinyurl.com/RhinelandRNA
October 21, 2025 at 10:17 AM
Don't miss our cool event in Cologne @mpiage.bsky.social on 14 November!
Reposted by Andreas Beyer Group
My lab @mpi-muenster.bsky.social is looking for a computational biologist with a passion for imaging and spatial biology. A staff scientist position with long-term perspective! Apply and spread the word 🙏 jobs.mpi-muenster.mpg.de/jobposting/0...
Computational image analyst (m/f/d)
The Max Planck Institute for Molecular Biomedicine in Münster, Germany, has an opening for a
jobs.mpi-muenster.mpg.de
September 12, 2025 at 6:17 AM
My lab @mpi-muenster.bsky.social is looking for a computational biologist with a passion for imaging and spatial biology. A staff scientist position with long-term perspective! Apply and spread the word 🙏 jobs.mpi-muenster.mpg.de/jobposting/0...
This review of our @crc1678.bsky.social member @bjornschumacher.bsky.social and @meyerdh.bsky.social is greatly summarizing fundamentals of the molecular biology of aging. What causes aging? Read the answer!
🔥🔥🔥Out now: our Perspectives article in @nataging.nature.com outlining how aging is driven by molecular damage leading to increasing molecular noise whose quantification could track aging with the precision of a clock @meyerdh.bsky.social @alexeimaklakov.bsky.social
www.nature.com/articles/s43...
www.nature.com/articles/s43...
Aging by the clock and yet without a program - Nature Aging
Meyer and colleagues refute the idea that, as aging can be tracked precisely by clocks, it must be driven by a biological program. They propose that imperfect maintenance and repair processes resultin...
www.nature.com
September 22, 2025 at 11:22 AM
This review of our @crc1678.bsky.social member @bjornschumacher.bsky.social and @meyerdh.bsky.social is greatly summarizing fundamentals of the molecular biology of aging. What causes aging? Read the answer!
Our PhD student @larahi.bsky.social l is now in Zurich @ethz.ch in the @picottilab.bsky.social with funding from @crc1678.bsky.social
Lara, enjoy your time on the Hönggerberg 🏔️ in one of the best proteomics labs of the world!! 🧪
Lara, enjoy your time on the Hönggerberg 🏔️ in one of the best proteomics labs of the world!! 🧪
September 7, 2025 at 4:56 PM
Our PhD student @larahi.bsky.social l is now in Zurich @ethz.ch in the @picottilab.bsky.social with funding from @crc1678.bsky.social
Lara, enjoy your time on the Hönggerberg 🏔️ in one of the best proteomics labs of the world!! 🧪
Lara, enjoy your time on the Hönggerberg 🏔️ in one of the best proteomics labs of the world!! 🧪
Reposted by Andreas Beyer Group
🚀 Don’t miss out the poster of our #CRC1678 member @nishahemandhar.bsky.social at the #EMBL Protein Conference — hands down, one of the most mind-blowing presentations out there! 🤯🤯
I'll be presenting our latest work, that explores proteo-transcriptomic changes that occur with brain aging and their impact on protein synthesis at the #EMBLProtein conference.
If you want to know more about it, come and spin my poster #129.
#proteinsynthesis #brainaging
If you want to know more about it, come and spin my poster #129.
#proteinsynthesis #brainaging
September 4, 2025 at 4:05 PM
🚀 Don’t miss out the poster of our #CRC1678 member @nishahemandhar.bsky.social at the #EMBL Protein Conference — hands down, one of the most mind-blowing presentations out there! 🤯🤯
Reposted by Andreas Beyer Group
📣CRC 1678 is funding research visits for three early career scientists!
🔬 @thancbn.bsky.social visits @landthalerm.bsky.social @ MDC Berlin
🧬 @larahi.bsky.social & Car Elias Kutzner visit @picottilab.bsky.social @ ETH Zürich
We wish our fellows an inspiring and productive time abroad!
🔬 @thancbn.bsky.social visits @landthalerm.bsky.social @ MDC Berlin
🧬 @larahi.bsky.social & Car Elias Kutzner visit @picottilab.bsky.social @ ETH Zürich
We wish our fellows an inspiring and productive time abroad!
August 29, 2025 at 10:02 AM
📣CRC 1678 is funding research visits for three early career scientists!
🔬 @thancbn.bsky.social visits @landthalerm.bsky.social @ MDC Berlin
🧬 @larahi.bsky.social & Car Elias Kutzner visit @picottilab.bsky.social @ ETH Zürich
We wish our fellows an inspiring and productive time abroad!
🔬 @thancbn.bsky.social visits @landthalerm.bsky.social @ MDC Berlin
🧬 @larahi.bsky.social & Car Elias Kutzner visit @picottilab.bsky.social @ ETH Zürich
We wish our fellows an inspiring and productive time abroad!
Congratulations to our new postdoc Domenico DiFraia for his amazing paper in @science.org! 🥂 A tour de force on brain aging in the killifish. 🐟 Transcriptomics, proteomics, including ribosome profiling, PTMs, etc... Translation is key for understanding brain aging!🧬🎉
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Altered translation elongation contributes to key hallmarks of aging in the killifish brain
Aging is a major risk factor for neurodegeneration and is characterized by diverse cellular and molecular hallmarks. To understand the origin of these hallmarks, we studied the effects of aging on the...
www.science.org
August 2, 2025 at 8:41 AM
Congratulations to our new postdoc Domenico DiFraia for his amazing paper in @science.org! 🥂 A tour de force on brain aging in the killifish. 🐟 Transcriptomics, proteomics, including ribosome profiling, PTMs, etc... Translation is key for understanding brain aging!🧬🎉
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Andreas Beyer Group
🧪Move over CUT&Tag, there’s a new #TranscriptionFactor mapping method in town.
Our newly developed DynaTag is faster, cleaner, more sensitive than #ChIPseq, #CUT&RUN and #CUT&Tag.
🔗 Our @natcomms.nature.com paper: www.nature.com/articles/s41...
🧵Let’s break down what makes DynaTag so powerful (1/7)
Our newly developed DynaTag is faster, cleaner, more sensitive than #ChIPseq, #CUT&RUN and #CUT&Tag.
🔗 Our @natcomms.nature.com paper: www.nature.com/articles/s41...
🧵Let’s break down what makes DynaTag so powerful (1/7)
July 28, 2025 at 9:10 AM
🧪Move over CUT&Tag, there’s a new #TranscriptionFactor mapping method in town.
Our newly developed DynaTag is faster, cleaner, more sensitive than #ChIPseq, #CUT&RUN and #CUT&Tag.
🔗 Our @natcomms.nature.com paper: www.nature.com/articles/s41...
🧵Let’s break down what makes DynaTag so powerful (1/7)
Our newly developed DynaTag is faster, cleaner, more sensitive than #ChIPseq, #CUT&RUN and #CUT&Tag.
🔗 Our @natcomms.nature.com paper: www.nature.com/articles/s41...
🧵Let’s break down what makes DynaTag so powerful (1/7)
Reposted by Andreas Beyer Group
🚨 Happy to share our first pre-print 🎉 on the causes of ribosome-associated degradation of CFTR and other transmembrane proteins.
We explore how protein folding, ER insertion, and elongation dynamics influence translation arrests in this new class of RQC targets.👇
www.biorxiv.org/content/10.1...
We explore how protein folding, ER insertion, and elongation dynamics influence translation arrests in this new class of RQC targets.👇
www.biorxiv.org/content/10.1...
Principles of ribosome-associated protein quality control during the synthesis of CFTR
Prolonged translational arrests caused by defective mRNAs activate the ribosome-associated protein quality control (RQC) pathway, which marks harmful incomplete proteins for degradation. Multipass tra...
www.biorxiv.org
August 1, 2025 at 10:36 AM
🚨 Happy to share our first pre-print 🎉 on the causes of ribosome-associated degradation of CFTR and other transmembrane proteins.
We explore how protein folding, ER insertion, and elongation dynamics influence translation arrests in this new class of RQC targets.👇
www.biorxiv.org/content/10.1...
We explore how protein folding, ER insertion, and elongation dynamics influence translation arrests in this new class of RQC targets.👇
www.biorxiv.org/content/10.1...
This was fantastic! So much fun, so nice people and a lot of exciting discussions about science, life and everything ✨🧬👩🔬🥂🎳 #CRC1678 #ECRetreat #ScienceCommunity
Today marks the first day of our very first CRC 1678 Early Career Researcher Retreat! We’re proud to have such an amazing group of scientists with us—full of curiosity, energy, and team spirit. 💥🧠 🥳💪 #CRC1678 #ECRetreat #ScienceCommunity
July 20, 2025 at 11:14 AM
This was fantastic! So much fun, so nice people and a lot of exciting discussions about science, life and everything ✨🧬👩🔬🥂🎳 #CRC1678 #ECRetreat #ScienceCommunity
Reposted by Andreas Beyer Group
Today marks the first day of our very first CRC 1678 Early Career Researcher Retreat! We’re proud to have such an amazing group of scientists with us—full of curiosity, energy, and team spirit. 💥🧠 🥳💪 #CRC1678 #ECRetreat #ScienceCommunity
July 14, 2025 at 6:38 PM
Today marks the first day of our very first CRC 1678 Early Career Researcher Retreat! We’re proud to have such an amazing group of scientists with us—full of curiosity, energy, and team spirit. 💥🧠 🥳💪 #CRC1678 #ECRetreat #ScienceCommunity
Reposted by Andreas Beyer Group
Freshly launched! 🚀 Check out the new CRC 1678 website 🌐
👉 crc1678.uni-koeln.de
👉 crc1678.uni-koeln.de
About CRC 1678 - CRC1678 - Collaborative Research Center
CRC 1678 investigates how age and stress-driven declines in the accuracy of mRNA and protein production affect cellular and organismal health. By taking an
crc1678.uni-koeln.de
July 11, 2025 at 3:48 PM
Freshly launched! 🚀 Check out the new CRC 1678 website 🌐
👉 crc1678.uni-koeln.de
👉 crc1678.uni-koeln.de
Reposted by Andreas Beyer Group
I am very proud to present you the first paper from the main research line of my group at the @mpiage.bsky.social in collaboration with my current group @molepi.bsky.social @bds-lumc.bsky.social at the LUMC, which is now published in @geroscience.bsky.social!
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Functional characterisation of rare variants in genes encoding the MAPK/ERK signalling pathway identified in long-lived Leiden Longevity Study participants - GeroScience
Human longevity, which is coupled to compression of age-related disease, is a heritable trait. However, only few common genetic variants have been linked to longevity, suggesting that rare, family-spe...
link.springer.com
May 29, 2025 at 7:50 PM
I am very proud to present you the first paper from the main research line of my group at the @mpiage.bsky.social in collaboration with my current group @molepi.bsky.social @bds-lumc.bsky.social at the LUMC, which is now published in @geroscience.bsky.social!
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Reposted by Andreas Beyer Group
🚨 Your PhD journey starts NOW! Join our #webinar on Sept 4, 1-3 PM (CEST) & explore #PhD opportunities at Max Planck's IMPRS in NRW, Germany! 🇩🇪
👀 Gain insights into groundbreaking research & register here: events.gwdg.de/e/PhDatMaxPl... #MaxPlanck #Research #Germany #Science
👀 Gain insights into groundbreaking research & register here: events.gwdg.de/e/PhDatMaxPl... #MaxPlanck #Research #Germany #Science
July 8, 2025 at 10:13 AM
🚨 Your PhD journey starts NOW! Join our #webinar on Sept 4, 1-3 PM (CEST) & explore #PhD opportunities at Max Planck's IMPRS in NRW, Germany! 🇩🇪
👀 Gain insights into groundbreaking research & register here: events.gwdg.de/e/PhDatMaxPl... #MaxPlanck #Research #Germany #Science
👀 Gain insights into groundbreaking research & register here: events.gwdg.de/e/PhDatMaxPl... #MaxPlanck #Research #Germany #Science
Welcome Alice! Great to have you here!
Currently our Mercator Fellow Alice E. Lee from Harvard Medical School is visiting us. We very much welcome Alice in Cologne and we are looking forward to many stimulating discussions with her! 👉 labs.childrenshospital.org/lee-lab
July 9, 2025 at 12:27 PM
Welcome Alice! Great to have you here!
Reposted by Andreas Beyer Group
Online now!✨RESEARCH: Gkioni et al @mpiage.bsky.social show that trametinib and rapamycin treatment combine additively to extend lifespan and healthspan in female and male mice, reducing tumor growth and inflammation www.nature.com/articles/s43... rdcu.be/eo3gS
The geroprotectors trametinib and rapamycin combine additively to extend mouse healthspan and lifespan - Nature Aging
Gkioni et al. show that trametinib, which targets the Ras–Mek–Erk pathway, extends lifespan in male and female mice and that co-treatment with the known geroprotector rapamycin additively extends life...
www.nature.com
June 2, 2025 at 10:24 AM
Online now!✨RESEARCH: Gkioni et al @mpiage.bsky.social show that trametinib and rapamycin treatment combine additively to extend lifespan and healthspan in female and male mice, reducing tumor growth and inflammation www.nature.com/articles/s43... rdcu.be/eo3gS
Reposted by Andreas Beyer Group
👏 Congratulations to Professor Aleksandra Trifunovic on receiving the Max Delbrück Research Prize 2025 from the University of Cologne for her groundbreaking work on #mitochondria, #aging, and cellular stress responses. A proud moment for #CECAD!
➡️ uni.koeln/Y6WSC
@unicologne.bsky.social
➡️ uni.koeln/Y6WSC
@unicologne.bsky.social
Aleksandra Trifunovic receives Max Delbrück Research Prize 2025
CECAD congratulates Professor Aleksandra Trifunovic on receiving the University of Cologne’s Max Delbrück Prize for her pioneering contributions to mitochondrial biology.
uni.koeln
May 19, 2025 at 11:31 AM
👏 Congratulations to Professor Aleksandra Trifunovic on receiving the Max Delbrück Research Prize 2025 from the University of Cologne for her groundbreaking work on #mitochondria, #aging, and cellular stress responses. A proud moment for #CECAD!
➡️ uni.koeln/Y6WSC
@unicologne.bsky.social
➡️ uni.koeln/Y6WSC
@unicologne.bsky.social
Reposted by Andreas Beyer Group
CECAD receives renewed DFG funding! 🎉 We continue to unlock the biology of aging 🧬 and advance healthy aging for all! 👵👴
➡️ uni.koeln/GAPGK
#CECAD #AgingResearch #ExcellenceCluster #DFG #HealthyAging @unicologne.bsky.social
➡️ uni.koeln/GAPGK
#CECAD #AgingResearch #ExcellenceCluster #DFG #HealthyAging @unicologne.bsky.social
May 22, 2025 at 3:23 PM
CECAD receives renewed DFG funding! 🎉 We continue to unlock the biology of aging 🧬 and advance healthy aging for all! 👵👴
➡️ uni.koeln/GAPGK
#CECAD #AgingResearch #ExcellenceCluster #DFG #HealthyAging @unicologne.bsky.social
➡️ uni.koeln/GAPGK
#CECAD #AgingResearch #ExcellenceCluster #DFG #HealthyAging @unicologne.bsky.social
This was a great event! Very inspiring and collaborative.
Great Minerva workshop on Biology of Healthy Aging by BIU and @cecad.bsky.social with Keynotes by Jan Hoeijmakers, Rafa de Cabo, @nirbarzilaimd.bsky.social and @garinis.bsky.social and the Cohen, @spanier55.bsky.social, @beyerlab.bsky.social, @eitanokun.bsky.social, Korenblit, Moran labs
May 22, 2025 at 5:47 PM
This was a great event! Very inspiring and collaborative.
Hurray!!!!! @cecad.bsky.social got another round of funding! Thanks to everyone involved and especially to Carien Niessen!
🎉Celebrating five Clusters of Excellence!
Congratulations to our Clusters: @cecad.bsky.social for aging research🧬, @ceplas.bsky.social for plant sciences🌱, @econtribute.bsky.social for economics, ML4Q for quantum research⚛️ and 🆕DYNAVERSE for astrophysics🌌
Read more ➡️https://uni.koeln/2AKU3
Congratulations to our Clusters: @cecad.bsky.social for aging research🧬, @ceplas.bsky.social for plant sciences🌱, @econtribute.bsky.social for economics, ML4Q for quantum research⚛️ and 🆕DYNAVERSE for astrophysics🌌
Read more ➡️https://uni.koeln/2AKU3
May 22, 2025 at 5:45 PM
Hurray!!!!! @cecad.bsky.social got another round of funding! Thanks to everyone involved and especially to Carien Niessen!
I highly recommend reading this.
I'd like to share this short piece on a topic I hope you will find useful. It is the result of a personl journey and many discussions with friends and peers. Let me know your thoughts.
network.febs.org/posts/the-pr...
network.febs.org/posts/the-pr...
The Professional Self: The Enemy Inside
network.febs.org
May 16, 2025 at 4:53 PM
I highly recommend reading this.