Benoit Miotto
@benoitmiotto.bsky.social
PI at Institut Cochin. CNRS, INSERM u1016, University Paris Cité. Focus on Epigenetics, DNA replication & diseases.
📌New paper📌
Targeting SUV4-20H Epigenetic Enzymes Enhances Topoisomerase II Poisoning in Prostate Cancer url: aacrjournals-org.insb.bib.cnrs.fr/cancerres/ar...
Targeting SUV4-20H Epigenetic Enzymes Enhances Topoisomerase II Poisoning in Prostate Cancer url: aacrjournals-org.insb.bib.cnrs.fr/cancerres/ar...
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aacrjournals-org.insb.bib.cnrs.fr
October 23, 2025 at 2:07 PM
📌New paper📌
Targeting SUV4-20H Epigenetic Enzymes Enhances Topoisomerase II Poisoning in Prostate Cancer url: aacrjournals-org.insb.bib.cnrs.fr/cancerres/ar...
Targeting SUV4-20H Epigenetic Enzymes Enhances Topoisomerase II Poisoning in Prostate Cancer url: aacrjournals-org.insb.bib.cnrs.fr/cancerres/ar...
Reposted by Benoit Miotto
Join us for this fantastic meeting in the heart of Paris with an amazing line up of dendritic cell and macrophage experts! And 2 Keynote speakers: Yasmine Belkaid and Dan Littman 🤩
🚨 The early bird registration deadline for the French DC Society meeting has been extended to October 24th, 2025!
Don’t miss the chance — register now!
Registration👇
docs.google.com/forms/d/e/1F...
Program 👇
www.cfcd.fr/meeting/prog...
Don’t miss the chance — register now!
Registration👇
docs.google.com/forms/d/e/1F...
Program 👇
www.cfcd.fr/meeting/prog...
October 18, 2025 at 1:06 PM
Join us for this fantastic meeting in the heart of Paris with an amazing line up of dendritic cell and macrophage experts! And 2 Keynote speakers: Yasmine Belkaid and Dan Littman 🤩
Reposted by Benoit Miotto
Come join us in Geneva for everything epigenetics and gene regulation. It will be a great meeting! Please repost!
www.keystonesymposia.org/conferences/...
www.keystonesymposia.org/conferences/...
Epigenetics and Gene Regulation in Health and Disease: Linking Basic Mechanisms with Therapeutic Opportunities | Keystone Symposia
Join us at the Keystone Symposia on Epigenetics and Gene Regulation in Health and Disease: Linking Basic Mechanisms with Therapeutic Opportunities, March 2026, in Geneva, with field leaders!
www.keystonesymposia.org
October 17, 2025 at 2:36 PM
Come join us in Geneva for everything epigenetics and gene regulation. It will be a great meeting! Please repost!
www.keystonesymposia.org/conferences/...
www.keystonesymposia.org/conferences/...
Reposted by Benoit Miotto
Consultez le programme complet de la #FDS2025 à l' @institutcochin.bsky.social :https://institutcochin.fr/lanimation/science-societe/fete-science/fete-science-2025
Rendez-vous tous, petits et grands, pour une plongée fascinante dans l’infiniment petit à l' @institutcochin.bsky.social
#FDS2025
#science
#microscopie 🔬
#Recherche
@inserm.fr
@cnrsbiologie.bsky.social
@upcite.bsky.social
#FDS2025
#science
#microscopie 🔬
#Recherche
@inserm.fr
@cnrsbiologie.bsky.social
@upcite.bsky.social
September 17, 2025 at 4:31 PM
Consultez le programme complet de la #FDS2025 à l' @institutcochin.bsky.social :https://institutcochin.fr/lanimation/science-societe/fete-science/fete-science-2025
RAD51 and Cancer. A must read by Bernard Lopez in Oncogene.
In a review article published in the Journal #Oncogene, Bernard Lopez proposes that #RAD51 -mediated homologous recombination is a Pro-tumour driver pathway, contradicting the generally accepted dogma
institutcochin.fr/en/news/plot...
@cnrsbiologie.bsky.social @inserm.fr @upcite.bsky.social
institutcochin.fr/en/news/plot...
@cnrsbiologie.bsky.social @inserm.fr @upcite.bsky.social
Plot twist: homologous recombination promotes cancer development
The prevailing view considers homologous recombination to be a tumour-suppressing mechanism. However, a re-analysis of data and concepts published in the journal Oncogene concludes that, in fact, homo...
institutcochin.fr
October 4, 2025 at 12:28 PM
RAD51 and Cancer. A must read by Bernard Lopez in Oncogene.
Targeting SUV4-20H Epigenetic Enzymes Enhances Topoisomerase II Poisoning in Prostate Cancer url: aacrjournals.org/cancerres/ar...
Targeting SUV4-20H Epigenetic Enzymes Enhances Topoisomerase II Poisoning in Prostate Cancer
Abstract. Commonly used in cancer therapy, topoisomerase II (TOP2) poisons are designed to stabilize the normally transient DNA TOP2 cleavage complexes in chromatin, leading to deleterious DNA double-...
aacrjournals.org
October 3, 2025 at 7:21 PM
Targeting SUV4-20H Epigenetic Enzymes Enhances Topoisomerase II Poisoning in Prostate Cancer url: aacrjournals.org/cancerres/ar...
Reposted by Benoit Miotto
Pleased to announce launching Institut Cochin Foundation, on Sept. 18 at 6 p.m., upon registration, either in the Rosalind Franklin room, 22 rue Méchain, Paris or via video conference: presentation of @institutcochin.bsky.social, meet researchers and call for donations-thanks for your support!
September 6, 2025 at 6:46 AM
Pleased to announce launching Institut Cochin Foundation, on Sept. 18 at 6 p.m., upon registration, either in the Rosalind Franklin room, 22 rue Méchain, Paris or via video conference: presentation of @institutcochin.bsky.social, meet researchers and call for donations-thanks for your support!
Reposted by Benoit Miotto
Pour ma part, j'ai toujours été pour le droit de mourir dans la dignité.
Mais il faut entendre les soignants, les malades et les personnes handicapées qui alertent : sans un système de santé capable d’accompagner dignement, la liberté de choisir sa fin existe t-elle réellement ?
Mais il faut entendre les soignants, les malades et les personnes handicapées qui alertent : sans un système de santé capable d’accompagner dignement, la liberté de choisir sa fin existe t-elle réellement ?
May 27, 2025 at 10:36 AM
Pour ma part, j'ai toujours été pour le droit de mourir dans la dignité.
Mais il faut entendre les soignants, les malades et les personnes handicapées qui alertent : sans un système de santé capable d’accompagner dignement, la liberté de choisir sa fin existe t-elle réellement ?
Mais il faut entendre les soignants, les malades et les personnes handicapées qui alertent : sans un système de santé capable d’accompagner dignement, la liberté de choisir sa fin existe t-elle réellement ?
Reposted by Benoit Miotto
Targeting SUV4-20H epigenetic enzymes as therapeutic strategy for enhancing topoisomerase II poisoning in prostate cancer https://www.biorxiv.org/content/10.1101/2025.03.11.642623v1
March 14, 2025 at 3:50 PM
Targeting SUV4-20H epigenetic enzymes as therapeutic strategy for enhancing topoisomerase II poisoning in prostate cancer https://www.biorxiv.org/content/10.1101/2025.03.11.642623v1
😍😍
Targeting SUV4-20H epigenetic enzymes as therapeutic strategy for enhancing topoisomerase II poisoning in prostate cancer https://www.biorxiv.org/content/10.1101/2025.03.11.642623v1
March 18, 2025 at 7:31 AM
😍😍
Reposted by Benoit Miotto
🌊 Nestled in the heart of the Calanques of Marseille, the IBDM offers an exceptional work environment 🌿✨
🔬 Conduct research with a sea view
🌞 Work in an inspiring natural setting
🌍 Combine scientific excellence with quality of life
Join us as a Group Leader: https://tinyurl.com/ukf2rn2x
🔬 Conduct research with a sea view
🌞 Work in an inspiring natural setting
🌍 Combine scientific excellence with quality of life
Join us as a Group Leader: https://tinyurl.com/ukf2rn2x
March 14, 2025 at 9:02 AM
🌊 Nestled in the heart of the Calanques of Marseille, the IBDM offers an exceptional work environment 🌿✨
🔬 Conduct research with a sea view
🌞 Work in an inspiring natural setting
🌍 Combine scientific excellence with quality of life
Join us as a Group Leader: https://tinyurl.com/ukf2rn2x
🔬 Conduct research with a sea view
🌞 Work in an inspiring natural setting
🌍 Combine scientific excellence with quality of life
Join us as a Group Leader: https://tinyurl.com/ukf2rn2x
Reposted by Benoit Miotto
Nature research paper: Mechanism for local attenuation of DNA replication at double-strand breaks
https://go.nature.com/4k8AdCX
https://go.nature.com/4k8AdCX
Mechanism for local attenuation of DNA replication at double-strand breaks - Nature
DNA double-strand breaks induce local genome maintenance and inhibition of replication initiation at nearby topologically associating domains without affecting global DNA synthesis.
go.nature.com
February 20, 2025 at 6:57 PM
Nature research paper: Mechanism for local attenuation of DNA replication at double-strand breaks
https://go.nature.com/4k8AdCX
https://go.nature.com/4k8AdCX
Reposted by Benoit Miotto
Interested in exploring epigenetic cell memory? Join us!! 6 PhD and postdoc positions available in our new center, EpiC.
🚨𝐌𝐚𝐣𝐨𝐫 𝐉𝐨𝐛 𝐀𝐥𝐞𝐫𝐭!🚨The Groth @groth-anja.bsky.social, Mailand, Nilsson @nilssonlab.bsky.social & Krietenstein @nilskrietenstein.bsky.social labs are hiring 𝟔 𝐏𝐡𝐃&𝐩𝐨𝐬𝐭𝐝𝐨𝐜𝐬 to join the new Center for Epigenetic Cell Memory (EpiC) in Copenhagen, Denmark. Apply here: tinyurl.com/yvd93na2 & please share!
6 Postdoctoral and PhD positions in Center for Epigenetic Cell Memory (EpiC)
The Center for Epigenetic Cell Memory (EpiC) is a new Center of Excellence that will be established based on funding by the Danish National Research Foundation.
tinyurl.com
February 12, 2025 at 11:11 PM
Interested in exploring epigenetic cell memory? Join us!! 6 PhD and postdoc positions available in our new center, EpiC.
Reposted by Benoit Miotto
The 4th of February is commemorated as World Cancer Day.
Cancer research is a strong focus of the Institut Cochin, with 15 teams involved in the studying molecular and cellular mechanisms that favor the development of cancers. A major aim of our research is to develop novel therapies.
Cancer research is a strong focus of the Institut Cochin, with 15 teams involved in the studying molecular and cellular mechanisms that favor the development of cancers. A major aim of our research is to develop novel therapies.
February 4, 2025 at 2:45 PM
The 4th of February is commemorated as World Cancer Day.
Cancer research is a strong focus of the Institut Cochin, with 15 teams involved in the studying molecular and cellular mechanisms that favor the development of cancers. A major aim of our research is to develop novel therapies.
Cancer research is a strong focus of the Institut Cochin, with 15 teams involved in the studying molecular and cellular mechanisms that favor the development of cancers. A major aim of our research is to develop novel therapies.
Reposted by Benoit Miotto
📢 We are recruiting group leaders!
We seek researchers who address fundamental questions in biology, including the development, the function, and the dynamics of complex biological systems.
APPLY before March 30th 2025 👉 www.ibdm.univ-amu.fr/we-are-recru...
#ScienceCareers #Marseille
We seek researchers who address fundamental questions in biology, including the development, the function, and the dynamics of complex biological systems.
APPLY before March 30th 2025 👉 www.ibdm.univ-amu.fr/we-are-recru...
#ScienceCareers #Marseille
January 21, 2025 at 8:58 AM
📢 We are recruiting group leaders!
We seek researchers who address fundamental questions in biology, including the development, the function, and the dynamics of complex biological systems.
APPLY before March 30th 2025 👉 www.ibdm.univ-amu.fr/we-are-recru...
#ScienceCareers #Marseille
We seek researchers who address fundamental questions in biology, including the development, the function, and the dynamics of complex biological systems.
APPLY before March 30th 2025 👉 www.ibdm.univ-amu.fr/we-are-recru...
#ScienceCareers #Marseille
Reposted by Benoit Miotto
We are looking for a #Postdoc to join our team to work on a funded project by La Ligue investigating the role of #gut permeability as a cause of #cancer with #age. 🐟🐟🐟
#zebrafish #telomerase #microbiome DEADLINE: 29/Jan/2025
Please help us spread the word! 🙏
#zebrafish #telomerase #microbiome DEADLINE: 29/Jan/2025
Please help us spread the word! 🙏
January 18, 2025 at 11:50 AM
We are looking for a #Postdoc to join our team to work on a funded project by La Ligue investigating the role of #gut permeability as a cause of #cancer with #age. 🐟🐟🐟
#zebrafish #telomerase #microbiome DEADLINE: 29/Jan/2025
Please help us spread the word! 🙏
#zebrafish #telomerase #microbiome DEADLINE: 29/Jan/2025
Please help us spread the word! 🙏
Reposted by Benoit Miotto
📣Paris-Munich Epigenetics (Workshop and Symposium)
📆 April 9-11, 2025
📍Buffon amphitheater, Université Paris Cité, France
Free of charge but registration is mandatory.
Deadline for abstract submissions and workshop applications is tomorrow
🔗 urls.fr/1VRiOh
📆 April 9-11, 2025
📍Buffon amphitheater, Université Paris Cité, France
Free of charge but registration is mandatory.
Deadline for abstract submissions and workshop applications is tomorrow
🔗 urls.fr/1VRiOh
January 14, 2025 at 9:17 AM
📣Paris-Munich Epigenetics (Workshop and Symposium)
📆 April 9-11, 2025
📍Buffon amphitheater, Université Paris Cité, France
Free of charge but registration is mandatory.
Deadline for abstract submissions and workshop applications is tomorrow
🔗 urls.fr/1VRiOh
📆 April 9-11, 2025
📍Buffon amphitheater, Université Paris Cité, France
Free of charge but registration is mandatory.
Deadline for abstract submissions and workshop applications is tomorrow
🔗 urls.fr/1VRiOh
Reposted by Benoit Miotto
📢 #Yeast2025 News!
Registration and abstract submission are NOW OPEN!
Join us at the 32nd ICYGMB
📅 Save the Date: 21-24 July 2025
📍 Location: Paris @sorbonne-universite.fr
🔗 Submit: premc.org/yeast2025/su...
🕒 Register now to take advantage of the Early Bird fee premc.org/yeast2025/re...
Registration and abstract submission are NOW OPEN!
Join us at the 32nd ICYGMB
📅 Save the Date: 21-24 July 2025
📍 Location: Paris @sorbonne-universite.fr
🔗 Submit: premc.org/yeast2025/su...
🕒 Register now to take advantage of the Early Bird fee premc.org/yeast2025/re...
January 14, 2025 at 7:28 AM
📢 #Yeast2025 News!
Registration and abstract submission are NOW OPEN!
Join us at the 32nd ICYGMB
📅 Save the Date: 21-24 July 2025
📍 Location: Paris @sorbonne-universite.fr
🔗 Submit: premc.org/yeast2025/su...
🕒 Register now to take advantage of the Early Bird fee premc.org/yeast2025/re...
Registration and abstract submission are NOW OPEN!
Join us at the 32nd ICYGMB
📅 Save the Date: 21-24 July 2025
📍 Location: Paris @sorbonne-universite.fr
🔗 Submit: premc.org/yeast2025/su...
🕒 Register now to take advantage of the Early Bird fee premc.org/yeast2025/re...
Reposted by Benoit Miotto
Please RT. Join the sixth edition of our Training Unit @institut_curie
international course on Genome Instability & Human Disease open to master students, PhDs and researchers! Amazing program. Registration dead line 2nd March 2025 at training.institut-curie.org/courses/geno...
international course on Genome Instability & Human Disease open to master students, PhDs and researchers! Amazing program. Registration dead line 2nd March 2025 at training.institut-curie.org/courses/geno...
January 4, 2025 at 11:42 AM
Please RT. Join the sixth edition of our Training Unit @institut_curie
international course on Genome Instability & Human Disease open to master students, PhDs and researchers! Amazing program. Registration dead line 2nd March 2025 at training.institut-curie.org/courses/geno...
international course on Genome Instability & Human Disease open to master students, PhDs and researchers! Amazing program. Registration dead line 2nd March 2025 at training.institut-curie.org/courses/geno...
Reposted by Benoit Miotto
@institutcochin.bsky.social is opening a position for a scientist wishing to establish his/her independent team. Application deadline 21/01/2025. For details and application:
institutcochin.fr/en/node/24264
institutcochin.fr/en/node/24264
December 6, 2024 at 3:37 PM
@institutcochin.bsky.social is opening a position for a scientist wishing to establish his/her independent team. Application deadline 21/01/2025. For details and application:
institutcochin.fr/en/node/24264
institutcochin.fr/en/node/24264
Reposted by Benoit Miotto
ok, I tried to make a starter pack on genome stability/DNA replication/DNA repair etc. Sorry if I couldn't find someone, please nominate yourself and your colleagues in comments or DMs, looking forward to connecting with everyone!
go.bsky.app/9jdDNxG
go.bsky.app/9jdDNxG
November 12, 2024 at 1:11 AM
ok, I tried to make a starter pack on genome stability/DNA replication/DNA repair etc. Sorry if I couldn't find someone, please nominate yourself and your colleagues in comments or DMs, looking forward to connecting with everyone!
go.bsky.app/9jdDNxG
go.bsky.app/9jdDNxG