@BaSyCresearch
@basycresearch.bsky.social
Building a Synthetic Cell (BaSyC) is a research programme with the goal of building an autonomous, self-reproducing synthetic cell.
www.basyc.nl
www.basyc.nl
www.sciencelink.net/verdieping/e...
Another interesting interview with Liedewij Laan (in Dutch).
Another interesting interview with Liedewij Laan (in Dutch).
‘Er zijn meerdere routes om als bèta impact te hebben’
Het is onder bèta's bon ton om te klagen over het gebrek aan bèta's bij de overheid. Tegelijkertijd wordt een loopbaan in beleid of bestuur door diezelfde groep nauwelijks voor vol aangezien. Die houding is natuurkundige Liedewij Laan een doorn in het oog.
www.sciencelink.net
November 3, 2025 at 10:14 AM
www.sciencelink.net/verdieping/e...
Another interesting interview with Liedewij Laan (in Dutch).
Another interesting interview with Liedewij Laan (in Dutch).
Nice interview with Liedewij Laan, Nico Claassens and Kristin Grußmayer (in Dutch): bionieuws.nl/article/1875...
Levensechte labcellen
DOOR RUBEN BOOT - ILLUSTRATIE: CEES DEKKER LAB / SCIXEL - 20-06-2025 - Celbiologie
bionieuws.nl
November 3, 2025 at 10:12 AM
Nice interview with Liedewij Laan, Nico Claassens and Kristin Grußmayer (in Dutch): bionieuws.nl/article/1875...
Reposted by @BaSyCresearch
Gisteren kunstproject 'Am I alive?' gezien van de enthousiaste 'Emergence' studenten van TUDelft & kunstacademies. Geïnspireerd door ons onderzoek hebben zij afgelopen half een installatie rond 'synthetische cellen' gebouwd
www.emergencedelft.nl/nmp4-synthet...
www.dehavenloods.nl/agenda/2025/...
www.emergencedelft.nl/nmp4-synthet...
www.dehavenloods.nl/agenda/2025/...
June 26, 2025 at 9:39 AM
Gisteren kunstproject 'Am I alive?' gezien van de enthousiaste 'Emergence' studenten van TUDelft & kunstacademies. Geïnspireerd door ons onderzoek hebben zij afgelopen half een installatie rond 'synthetische cellen' gebouwd
www.emergencedelft.nl/nmp4-synthet...
www.dehavenloods.nl/agenda/2025/...
www.emergencedelft.nl/nmp4-synthet...
www.dehavenloods.nl/agenda/2025/...
Reposted by @BaSyCresearch
Building a synthetic cell together - nice common perspective written by many leading scientists who gathered in Shenzhen China for the inaugural ‘SynCell Global Summit’.
Check it out in Nature Comm: www.nature.com/articles/s41...
Check it out in Nature Comm: www.nature.com/articles/s41...
August 13, 2025 at 7:19 AM
Building a synthetic cell together - nice common perspective written by many leading scientists who gathered in Shenzhen China for the inaugural ‘SynCell Global Summit’.
Check it out in Nature Comm: www.nature.com/articles/s41...
Check it out in Nature Comm: www.nature.com/articles/s41...
Reposted by @BaSyCresearch
WORK: 5 (!) openings in our #CDlab, check it out: ceesdekkerlab.nl/come-join-us/
August 22, 2025 at 8:38 AM
WORK: 5 (!) openings in our #CDlab, check it out: ceesdekkerlab.nl/come-join-us/
Reposted by @BaSyCresearch
As in so many ways I very much still feel like a novice student in exploring biology, I am very grateful and proud for this Award of the Biochemical Society 'for significant achievements in nanoscale molecular biology, especially the contribution to developing methodologies'.
Congratulations to Cees Dekker @ceesdekker.bsky.social who showcased his work on single-molecule biophysics studies of DNA loop extrusion in his 2026 #BiochemAward Lecture for Significant Breakthrough or Achievement! We hope everyone enjoyed Prokaryotic Chromosomes VII!
September 19, 2025 at 12:46 PM
As in so many ways I very much still feel like a novice student in exploring biology, I am very grateful and proud for this Award of the Biochemical Society 'for significant achievements in nanoscale molecular biology, especially the contribution to developing methodologies'.
Congrats @ceesdekker.bsky.social! 🎉
Cornelis (Cees) Dekker to Receive the 2026 Kazuhiko Kinosita Award in Single-Molecule Biophysics buff.ly/fIexyZu
September 29, 2025 at 10:40 AM
Congrats @ceesdekker.bsky.social! 🎉
Nice article from @mkeulemans.bsky.social who interviews BaSyC PI John van der Oost (in Dutch) www.volkskrant.nl/wetenschap/a...
Als grondlegger van het revolutionaire knippen in DNA greep hij net naast de Nobelprijs. Maar wie weet wat er nog komt…
Scheidend hoogleraar John van der Oost stond aan de basis van de grootste biologische doorbraak van afgelopen decennia – de Nobelprijs ontglipte hem maar net. De echte DNA-revolutie moet nog komen, ze...
www.volkskrant.nl
August 20, 2025 at 2:44 PM
Nice article from @mkeulemans.bsky.social who interviews BaSyC PI John van der Oost (in Dutch) www.volkskrant.nl/wetenschap/a...
Another BaSyC PhD thesis defense coming up! 🙂
Céline Cleij will defend her PhD thesis 🎓on 18 September 2025 at 12:30 in Delft. Title of her dissertation: ‘Building the genome of a minimal synthetic cell’.
Good luck Céline!
Céline Cleij will defend her PhD thesis 🎓on 18 September 2025 at 12:30 in Delft. Title of her dissertation: ‘Building the genome of a minimal synthetic cell’.
Good luck Céline!
August 20, 2025 at 11:49 AM
Another BaSyC PhD thesis defense coming up! 🙂
Céline Cleij will defend her PhD thesis 🎓on 18 September 2025 at 12:30 in Delft. Title of her dissertation: ‘Building the genome of a minimal synthetic cell’.
Good luck Céline!
Céline Cleij will defend her PhD thesis 🎓on 18 September 2025 at 12:30 in Delft. Title of her dissertation: ‘Building the genome of a minimal synthetic cell’.
Good luck Céline!
BaSyC PhD thesis defense coming up! 🙂
Yash Jawale will defend his PhD thesis 🎓on 12 September 2025 at 12:30 in Delft. Title of his dissertation: ‘Building Minimal Spindles: Reconstituting spindle positioning in synthetic cells’. Good luck @ykjawale.bsky.social!
Yash Jawale will defend his PhD thesis 🎓on 12 September 2025 at 12:30 in Delft. Title of his dissertation: ‘Building Minimal Spindles: Reconstituting spindle positioning in synthetic cells’. Good luck @ykjawale.bsky.social!
August 20, 2025 at 11:43 AM
BaSyC PhD thesis defense coming up! 🙂
Yash Jawale will defend his PhD thesis 🎓on 12 September 2025 at 12:30 in Delft. Title of his dissertation: ‘Building Minimal Spindles: Reconstituting spindle positioning in synthetic cells’. Good luck @ykjawale.bsky.social!
Yash Jawale will defend his PhD thesis 🎓on 12 September 2025 at 12:30 in Delft. Title of his dissertation: ‘Building Minimal Spindles: Reconstituting spindle positioning in synthetic cells’. Good luck @ykjawale.bsky.social!
Congrats Timon!
Delighted to announce that I'm awarded an @nronl.bsky.social Comenius Leadership Fellow grant to work on co-creation of interactive open textbooks as an educational tool. Excited to explore this with and for our students in the coming years. See edu.nl/w78qp for a description of the project.
Comenius Fellows
edu.nl
July 16, 2025 at 11:24 AM
Congrats Timon!
Nice picture taken during the BaSyC/EVOLF spring meeting last month! In the picture the EVOLF community, growing rapidly 👭👫👬
Onze EVOLF community groeit flink, zie bv deze foto van ons overleg gisteren
#EvolvingLIfeFromNonlife
#EvolvingLIfeFromNonlife
July 16, 2025 at 11:10 AM
Nice picture taken during the BaSyC/EVOLF spring meeting last month! In the picture the EVOLF community, growing rapidly 👭👫👬
Reposted by @BaSyCresearch
Just spoke with PhD student Olga Rook.
She did a survey on public attitudes to synthetic cells, see journals.plos.org/plosone/arti...
Overall she finds great support, with only ~10% of people objecting to synthetic cell research and applications.
She did a survey on public attitudes to synthetic cells, see journals.plos.org/plosone/arti...
Overall she finds great support, with only ~10% of people objecting to synthetic cell research and applications.
June 17, 2025 at 12:24 PM
Just spoke with PhD student Olga Rook.
She did a survey on public attitudes to synthetic cells, see journals.plos.org/plosone/arti...
Overall she finds great support, with only ~10% of people objecting to synthetic cell research and applications.
She did a survey on public attitudes to synthetic cells, see journals.plos.org/plosone/arti...
Overall she finds great support, with only ~10% of people objecting to synthetic cell research and applications.
BPS2026 Annual meeting is in San Francisco next year from 21-25 February.
BPS is in San Francisco next year! www.biophysics.org/2026meeting
BPS2026 Annual Meeting | Biophysical Society
www.biophysics.org
July 16, 2025 at 10:57 AM
BPS2026 Annual meeting is in San Francisco next year from 21-25 February.
Reposted by @BaSyCresearch
Telomeres stall DNA loop extrusion by condensin
Telomeres stall DNA loop extrusion by condensin
Analikwu et al. show that dense linear arrays of the telomeric protein Rap1 on DNA block DNA loop extrusion by condensin. Rap1-induced stalling depends on array length and protein density and leads to a local chromatin decompaction during anaphase, revealing how protein arrays can regulate SMC-driven genome organization.
dlvr.it
July 2, 2025 at 7:50 PM
Telomeres stall DNA loop extrusion by condensin
Reposted by @BaSyCresearch
SynCell conferences - Save the dates!
SynCell2025: 9-11 September 2025 at Stanford, USA.
Further info: www.buildacell.org/syncell2025
SynCell2026: 22-24 April 2026, Institute of Physics in London, UK. Registration opens in Autumn 2025. More info will follow in due course at syntheticcell.eu
SynCell2025: 9-11 September 2025 at Stanford, USA.
Further info: www.buildacell.org/syncell2025
SynCell2026: 22-24 April 2026, Institute of Physics in London, UK. Registration opens in Autumn 2025. More info will follow in due course at syntheticcell.eu
April 10, 2025 at 12:27 PM
SynCell conferences - Save the dates!
SynCell2025: 9-11 September 2025 at Stanford, USA.
Further info: www.buildacell.org/syncell2025
SynCell2026: 22-24 April 2026, Institute of Physics in London, UK. Registration opens in Autumn 2025. More info will follow in due course at syntheticcell.eu
SynCell2025: 9-11 September 2025 at Stanford, USA.
Further info: www.buildacell.org/syncell2025
SynCell2026: 22-24 April 2026, Institute of Physics in London, UK. Registration opens in Autumn 2025. More info will follow in due course at syntheticcell.eu
Reposted by @BaSyCresearch
Let's get an update on @comeincell.bsky.social, the MSCA doctoral network that aims to develop advanced cellular mimics to shed light on complex cellular mechanisms and accelerate innovation. We interviewed Rumiana @dimovalab.bsky.social, the consortium's coordinator
syntheticcell.eu/update-on-co...
syntheticcell.eu/update-on-co...
Update on ComeInCell, MSCA Doctoral Network
Interview with Rumiana Dimova on ComeInCell, a doctoral network to shed light on complex cellular mechanisms and accelerate innovation
syntheticcell.eu
May 1, 2025 at 12:33 PM
Let's get an update on @comeincell.bsky.social, the MSCA doctoral network that aims to develop advanced cellular mimics to shed light on complex cellular mechanisms and accelerate innovation. We interviewed Rumiana @dimovalab.bsky.social, the consortium's coordinator
syntheticcell.eu/update-on-co...
syntheticcell.eu/update-on-co...
Reposted by @BaSyCresearch
Wow, I feel greatly honored by being awarded the 2026 Biochemical Society Award for Significant Breakthrough or Achievement, as was just announced!
www.biochemistry.org/about-us/new...
It is wonderful that the Biochemical Society honors our contributions to single-molecule biophysics in this way!
www.biochemistry.org/about-us/new...
It is wonderful that the Biochemical Society honors our contributions to single-molecule biophysics in this way!
The 2026 Biochemical Society Award for Significant Breakthrough or Achievement is presented to Cees Dekker @ceesdekker.bsky.social! Celebrating his ground-breaking contributions to nanotechnology, Cees has pioneered research on solid-state nanopores and nanopore-based DNA sequencing.
April 8, 2025 at 8:30 AM
Wow, I feel greatly honored by being awarded the 2026 Biochemical Society Award for Significant Breakthrough or Achievement, as was just announced!
www.biochemistry.org/about-us/new...
It is wonderful that the Biochemical Society honors our contributions to single-molecule biophysics in this way!
www.biochemistry.org/about-us/new...
It is wonderful that the Biochemical Society honors our contributions to single-molecule biophysics in this way!
Reposted by @BaSyCresearch
Now out in print, our review 'Single-molecule protein sequencing with nanopores' in Nature Reviews Bioengineering: www.nature.com/articles/s44...
April 14, 2025 at 3:06 PM
Now out in print, our review 'Single-molecule protein sequencing with nanopores' in Nature Reviews Bioengineering: www.nature.com/articles/s44...
Congrats @ceesdekker.bsky.social!
Congratulations to @ceesdekker.bsky.social #TUDelft, winner of the 2026 Biochemical Society Award for a Significant Breakthrough or Achievement! www.biochemistry.org/about-us/new...
#nanopores for #proteinsequencing; #chromosome structure; #building living #syntheticcell from lifeless #molecules.
#nanopores for #proteinsequencing; #chromosome structure; #building living #syntheticcell from lifeless #molecules.
Biochemical Society announces 2026 award recipients
Following another record year of nominations, the work and contribution of seventeen eminent bioscientists, outstanding educators and exceptional early career researchers has been acknowledged in the ...
www.biochemistry.org
May 8, 2025 at 12:37 PM
Congrats @ceesdekker.bsky.social!
Nice coverstory in Pioneering Tech (ENG+NL) about the synthetic cell: 'Factory of the future' with BaSyC PI Marileen Dogterom @marileend.bsky.social (and check out the brand new image of synthetic cells from BaSyC PhD Federico Ramirez Gomez (Koenderink & Danelon labs).
The factory of the future is a synthetic cell, these cells can become efficient and sustainable factories a.o. extract a lot of #CO2 from the air. Article in #PioneeringTech #TUDelft with @marileend.bsky.social, professor #Bionanoscience at TU Delft www.tudelft.nl/en/innovatio...
The factory of the future is a synthetic cell
So far, synthetic cells have been cause for excitement, especially for fundamental scientists. But take note: they can become efficient and sustainable factories that make all kinds of things for us a...
www.tudelft.nl
May 8, 2025 at 12:29 PM
Nice coverstory in Pioneering Tech (ENG+NL) about the synthetic cell: 'Factory of the future' with BaSyC PI Marileen Dogterom @marileend.bsky.social (and check out the brand new image of synthetic cells from BaSyC PhD Federico Ramirez Gomez (Koenderink & Danelon labs).
Reposted by @BaSyCresearch
Interested in engineering bacteria to turn #C1feedstocks into high-value chemicals for #bioproduction? Here is a thread summarizing our latest review on the roadblocks and how we might bio-hack our way past them 🧵 1/n academic.oup.com/femsre/advan...
Seven Critical Challenges in Synthetic One-Carbon Assimilation and Their Potential Solutions
Abstract. Synthetic C1 assimilation holds the promise of facilitating carbon capture while mitigating greenhouse gas emissions, yet practical implementatio
academic.oup.com
April 4, 2025 at 11:19 AM
Interested in engineering bacteria to turn #C1feedstocks into high-value chemicals for #bioproduction? Here is a thread summarizing our latest review on the roadblocks and how we might bio-hack our way past them 🧵 1/n academic.oup.com/femsre/advan...
Reposted by @BaSyCresearch
Onderzoeker en viroloog John van der Oost wint de #Beijerinck #Virologie Prijs voor zijn CRISPR-Cas onderzoek. Early career onderzoekers Carmen Embregts & Puck van Kasteren ontvangen de #BeijerinckPremie. www.knaw.nl/nieuws/voorb... @rdo-erasmusmc.bsky.social @rivm-nl.bsky.social @w-u-r.bsky.social
February 11, 2025 at 10:48 AM
Onderzoeker en viroloog John van der Oost wint de #Beijerinck #Virologie Prijs voor zijn CRISPR-Cas onderzoek. Early career onderzoekers Carmen Embregts & Puck van Kasteren ontvangen de #BeijerinckPremie. www.knaw.nl/nieuws/voorb... @rdo-erasmusmc.bsky.social @rivm-nl.bsky.social @w-u-r.bsky.social
Reposted by @BaSyCresearch
Latest #CDlab paper online in @labonachip.rsc.org: pubs.rsc.org/en/content/a...
Here, 1st authors Alex Joesaar & Martin Holub developed a microfluidics platform to extract and study full length megabase-size genomes in microfluidic chambers (where they are protected against shearing by flow)!
Here, 1st authors Alex Joesaar & Martin Holub developed a microfluidics platform to extract and study full length megabase-size genomes in microfluidic chambers (where they are protected against shearing by flow)!
March 3, 2025 at 9:13 AM
Latest #CDlab paper online in @labonachip.rsc.org: pubs.rsc.org/en/content/a...
Here, 1st authors Alex Joesaar & Martin Holub developed a microfluidics platform to extract and study full length megabase-size genomes in microfluidic chambers (where they are protected against shearing by flow)!
Here, 1st authors Alex Joesaar & Martin Holub developed a microfluidics platform to extract and study full length megabase-size genomes in microfluidic chambers (where they are protected against shearing by flow)!