Gert Bange
@bangebalcony.bsky.social
Professor and Vice President for Research at University of Marburg. Proud member of SYNMIKRO. Fellow at the Max Planck Institute for terrestrial Microbiology. Interested in the response of organisms to stress.
http://www.bangelab.org
http://www.bangelab.org
In @elife.bsky.social: Membrane binding properties of the cytoskeletal protein bactofilin doi.org/10.7554/eLif...
Membrane binding properties of the cytoskeletal protein bactofilin
A combination of cell biological, biochemical, and computational approaches characterizes the conserved membrane-targeting sequence of bactofilins and reveals a mutual influence of membrane binding an...
doi.org
September 19, 2025 at 9:51 PM
In @elife.bsky.social: Membrane binding properties of the cytoskeletal protein bactofilin doi.org/10.7554/eLif...
Reposted by Gert Bange
How do beneficial gut microbes 'read' their habitat? A study by Victor Sourjik`s lab together with @bangebalcony.bsky.social investigated the chemical preferences of gut microbes. The study highlights the important role of #microbes in #health and #ecosystems. 👉 s.academiccloud.de/zSKBRb
What Gut Bacteria Like
An international team of researchers has addressed a question that has received little attention to date: how do beneficial gut microorganisms perceive their environment? Led by Prof. Dr Victor Sourji...
www.mpi-marburg.mpg.de
August 27, 2025 at 10:32 AM
How do beneficial gut microbes 'read' their habitat? A study by Victor Sourjik`s lab together with @bangebalcony.bsky.social investigated the chemical preferences of gut microbes. The study highlights the important role of #microbes in #health and #ecosystems. 👉 s.academiccloud.de/zSKBRb
Reposted by Gert Bange
It is out now 🥳🥂
I am very happy to be part of this nice collaboration in which we were able to characterize different bacterial chemoreceptors and their ligand specificities. Amazing teamwork with Wenhao Xu, the Sourjik lab, @bangebalcony.bsky.social, et. al 🤩
👇👇👇
www.pnas.org/doi/10.1073/...
I am very happy to be part of this nice collaboration in which we were able to characterize different bacterial chemoreceptors and their ligand specificities. Amazing teamwork with Wenhao Xu, the Sourjik lab, @bangebalcony.bsky.social, et. al 🤩
👇👇👇
www.pnas.org/doi/10.1073/...
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
August 26, 2025 at 9:06 PM
It is out now 🥳🥂
I am very happy to be part of this nice collaboration in which we were able to characterize different bacterial chemoreceptors and their ligand specificities. Amazing teamwork with Wenhao Xu, the Sourjik lab, @bangebalcony.bsky.social, et. al 🤩
👇👇👇
www.pnas.org/doi/10.1073/...
I am very happy to be part of this nice collaboration in which we were able to characterize different bacterial chemoreceptors and their ligand specificities. Amazing teamwork with Wenhao Xu, the Sourjik lab, @bangebalcony.bsky.social, et. al 🤩
👇👇👇
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/... @synmikro.bsky.social @unimarburg.bsky.social @mpimicrobiomarburg.bsky.social
Specificities of chemosensory receptors in the human gut microbiota | PNAS
The human gut is rich in metabolites and harbors a complex microbial community, yet
surprisingly little is known about the spectrum of chemical sig...
www.pnas.org
August 26, 2025 at 7:20 PM
In @elife.bsky.social: Membrane binding properties of the cytoskeletal protein bactofilin doi.org/10.7554/eLif... @synmikro.bsky.social @unimarburg.bsky.social
doi.org
August 21, 2025 at 9:57 PM
In @elife.bsky.social: Membrane binding properties of the cytoskeletal protein bactofilin doi.org/10.7554/eLif... @synmikro.bsky.social @unimarburg.bsky.social
Reposted by Gert Bange
👍🏼COOL🆕Christof Wegscheid-Gerlach @cwgmr.bsky.social (Koord. d. eh.LOEWE-GLUE) übernimmt Staffelstab🧪von Prof. Stefanie Dehnen (ehem.👩🏼🔬bei LOEWE-MOSLA, heute Direktorin des Instituts für Nanotechnologie am KIT in Karlsruhe).Wir gratulieren dem🆕Direktor des Chemikum #Marburg!!! @unimarburg.bsky.social
August 12, 2025 at 4:30 PM
👍🏼COOL🆕Christof Wegscheid-Gerlach @cwgmr.bsky.social (Koord. d. eh.LOEWE-GLUE) übernimmt Staffelstab🧪von Prof. Stefanie Dehnen (ehem.👩🏼🔬bei LOEWE-MOSLA, heute Direktorin des Instituts für Nanotechnologie am KIT in Karlsruhe).Wir gratulieren dem🆕Direktor des Chemikum #Marburg!!! @unimarburg.bsky.social
Reposted by Gert Bange
From bacterial virulence to human disease, researchers gathered in Marburg exploring how Ap₄A and other dinucleoside polyphosphates are rewriting the rules of cellular signaling across life. 🚀 Huge thanks to all speakers, participants, and organizers. 🙌 @synmikro.bsky.social @unimarburg.bsky.social
Dinucleoside Polyphosphates in Cellular Signaling: Function and Evolution Across Life
Although discovered more than 50 years ago, the cellular functions of Ap4A and related dinucleotides remain largely enigmatic. To address this knowledge gap, we organized a conference showcasing rece....
onlinelibrary.wiley.com
August 8, 2025 at 10:28 AM
From bacterial virulence to human disease, researchers gathered in Marburg exploring how Ap₄A and other dinucleoside polyphosphates are rewriting the rules of cellular signaling across life. 🚀 Huge thanks to all speakers, participants, and organizers. 🙌 @synmikro.bsky.social @unimarburg.bsky.social
From bacterial virulence to human disease, researchers gathered in Marburg exploring how Ap₄A and other dinucleoside polyphosphates are rewriting the rules of cellular signaling across life. 🚀 Huge thanks to all speakers, participants, and organizers. 🙌 @synmikro.bsky.social @unimarburg.bsky.social
Dinucleoside Polyphosphates in Cellular Signaling: Function and Evolution Across Life
Although discovered more than 50 years ago, the cellular functions of Ap4A and related dinucleotides remain largely enigmatic. To address this knowledge gap, we organized a conference showcasing rece....
onlinelibrary.wiley.com
August 8, 2025 at 10:28 AM
From bacterial virulence to human disease, researchers gathered in Marburg exploring how Ap₄A and other dinucleoside polyphosphates are rewriting the rules of cellular signaling across life. 🚀 Huge thanks to all speakers, participants, and organizers. 🙌 @synmikro.bsky.social @unimarburg.bsky.social
Reposted by Gert Bange
🍾 GOOD🆕s:➡️𝗗ü𝗿𝗿𝗲𝗮𝗻𝗽𝗮𝘀𝘀𝘂𝗻𝗴➡️𝗔𝗻𝘁𝗶𝗳𝗲𝗺𝗶𝗻𝗶𝘀𝗺𝗲𝗻➡️𝗽𝗲𝗿𝘀𝗼𝗻𝗮𝗹is. 𝗠𝗲𝗱𝗶𝘇𝗶𝗻𝘁𝗲𝗰𝗵𝗻𝗶𝗸: 38𝗠𝗶𝗼.€ 𝗳ü𝗿 hess.F𝗼𝗿𝘀𝗰𝗵𝘂𝗻𝗴:1️⃣𝗟𝗢𝗘𝗪𝗘-𝗭𝗲𝗻𝘁𝗿𝘂𝗺,4️⃣𝗦𝗰𝗵𝘄𝗲𝗿𝗽𝘂𝗻𝗸𝘁𝗲+🔟𝗟𝗢𝗘𝗪𝗘-𝗣𝗿𝗼𝗷𝗲𝗸𝘁𝗲-𝗪𝗶𝗿 🫶🏼 𝗴𝗿𝗮𝘁𝘂𝗹𝗶𝗲𝗿𝗲𝗻! @tuda.bsky.social @jlugiessen.bsky.social @goetheuni.bsky.social @unikassel.bsky.social @unimarburg.bsky.social ➡️ wissenschaft.hessen.de
July 29, 2025 at 9:42 AM
🍾 GOOD🆕s:➡️𝗗ü𝗿𝗿𝗲𝗮𝗻𝗽𝗮𝘀𝘀𝘂𝗻𝗴➡️𝗔𝗻𝘁𝗶𝗳𝗲𝗺𝗶𝗻𝗶𝘀𝗺𝗲𝗻➡️𝗽𝗲𝗿𝘀𝗼𝗻𝗮𝗹is. 𝗠𝗲𝗱𝗶𝘇𝗶𝗻𝘁𝗲𝗰𝗵𝗻𝗶𝗸: 38𝗠𝗶𝗼.€ 𝗳ü𝗿 hess.F𝗼𝗿𝘀𝗰𝗵𝘂𝗻𝗴:1️⃣𝗟𝗢𝗘𝗪𝗘-𝗭𝗲𝗻𝘁𝗿𝘂𝗺,4️⃣𝗦𝗰𝗵𝘄𝗲𝗿𝗽𝘂𝗻𝗸𝘁𝗲+🔟𝗟𝗢𝗘𝗪𝗘-𝗣𝗿𝗼𝗷𝗲𝗸𝘁𝗲-𝗪𝗶𝗿 🫶🏼 𝗴𝗿𝗮𝘁𝘂𝗹𝗶𝗲𝗿𝗲𝗻! @tuda.bsky.social @jlugiessen.bsky.social @goetheuni.bsky.social @unikassel.bsky.social @unimarburg.bsky.social ➡️ wissenschaft.hessen.de
Reposted by Gert Bange
Rebekka is presenting their recent publication in #NAR
academic.oup.com/nar/article/...
Collaboration with @thanbichlerlab.bsky.social and also with @bangebalcony.bsky.social - thus beautiful crystal structures involved
#BACELL2025
academic.oup.com/nar/article/...
Collaboration with @thanbichlerlab.bsky.social and also with @bangebalcony.bsky.social - thus beautiful crystal structures involved
#BACELL2025
A conserved nuclease facilitates environmental DNA uptake
Abstract. Bacteria acquire new traits through the uptake of genetic material from the environment, a process requiring DNA processing. However, the molecul
academic.oup.com
June 18, 2025 at 9:48 AM
Rebekka is presenting their recent publication in #NAR
academic.oup.com/nar/article/...
Collaboration with @thanbichlerlab.bsky.social and also with @bangebalcony.bsky.social - thus beautiful crystal structures involved
#BACELL2025
academic.oup.com/nar/article/...
Collaboration with @thanbichlerlab.bsky.social and also with @bangebalcony.bsky.social - thus beautiful crystal structures involved
#BACELL2025
Reposted by Gert Bange
Thank you for being a part of RobuCop!@olallalab.bsky.social @bangebalcony.bsky.social @danielschindler.bsky.social @hoeferlab.bsky.social @schullerjm.bsky.social @georghochberg.bsky.social
May 22, 2025 at 7:31 AM
Thank you for being a part of RobuCop!@olallalab.bsky.social @bangebalcony.bsky.social @danielschindler.bsky.social @hoeferlab.bsky.social @schullerjm.bsky.social @georghochberg.bsky.social
Reposted by Gert Bange
If you want to know how to tell an N from an O, you can get some ideas in our new paper. This was a great team effort, introducing us to new methods: MD w/ Ferran Feixas & Marc Garcia Borràs (Girona) + HDX-MS w/ Wieland Steinchen & Gert Bange @bangebalcony.bsky.social
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...
How to Tell an N from an O: Controlling the Chemoselectivity of Methyltransferases
S-Adenosyl-l-methionine (SAM)-dependent methyltransferases (MTs) are important enzymes in numerous biological pathways. They share a common SN2 mechanism but act on different nucleophilic substrates i...
pubs.acs.org
April 4, 2025 at 3:36 PM
If you want to know how to tell an N from an O, you can get some ideas in our new paper. This was a great team effort, introducing us to new methods: MD w/ Ferran Feixas & Marc Garcia Borràs (Girona) + HDX-MS w/ Wieland Steinchen & Gert Bange @bangebalcony.bsky.social
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...
Reposted by Gert Bange
Prophages in the infant gut are pervasively induced and may modulate the functionality of their hosts
NPJ Biofilms and Microbiomes - from Copenhagen University Hospital and University of Copenhagen
www.nature.com/articles/s41...
NPJ Biofilms and Microbiomes - from Copenhagen University Hospital and University of Copenhagen
www.nature.com/articles/s41...
Prophages in the infant gut are pervasively induced and may modulate the functionality of their hosts - npj Biofilms and Microbiomes
npj Biofilms and Microbiomes - Prophages in the infant gut are pervasively induced and may modulate the functionality of their hosts
www.nature.com
March 22, 2025 at 9:33 AM
Prophages in the infant gut are pervasively induced and may modulate the functionality of their hosts
NPJ Biofilms and Microbiomes - from Copenhagen University Hospital and University of Copenhagen
www.nature.com/articles/s41...
NPJ Biofilms and Microbiomes - from Copenhagen University Hospital and University of Copenhagen
www.nature.com/articles/s41...
A doctor is born: congratulations Victor Zegarra!!! @synmikro.bsky.social @unimarburg.bsky.social
March 17, 2025 at 3:05 PM
A doctor is born: congratulations Victor Zegarra!!! @synmikro.bsky.social @unimarburg.bsky.social
Reposted by Gert Bange
🫴 Mechanistic insights into the regulatory framework underlying acetyl-CoA biosynthesis from acetate in Bacillus subtilis:
👇👇👇
www.nature.com/articles/s41...
@bangebalcony.bsky.social #subtiwiki #subtilis @naturecomms.bsky.social
👇👇👇
www.nature.com/articles/s41...
@bangebalcony.bsky.social #subtiwiki #subtilis @naturecomms.bsky.social
Regulation of acetyl-CoA biosynthesis via an intertwined acetyl-CoA synthetase/acetyltransferase complex - Nature Communications
Here the authors investigate the regulatory mechanisms of acetyl-CoA (Ac-CoA) biosynthesis in Bacillus subtilis, probing the interaction between acetyl-CoA synthetase (AcsA) and acetyltransferase (Acu...
www.nature.com
March 17, 2025 at 10:21 AM
🫴 Mechanistic insights into the regulatory framework underlying acetyl-CoA biosynthesis from acetate in Bacillus subtilis:
👇👇👇
www.nature.com/articles/s41...
@bangebalcony.bsky.social #subtiwiki #subtilis @naturecomms.bsky.social
👇👇👇
www.nature.com/articles/s41...
@bangebalcony.bsky.social #subtiwiki #subtilis @naturecomms.bsky.social
Reposted by Gert Bange
Happy to share our latest @biorxiv-plants.bsky.social led by @manuelgonzalezfuen.bsky.social “Effector-triggered processing body formation attenuates host translation via ER stress responses and autophagy upon bacterial infection” #proteostasis #plantimmunity 🧵(1/16)
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
January 14, 2025 at 4:35 PM
Happy to share our latest @biorxiv-plants.bsky.social led by @manuelgonzalezfuen.bsky.social “Effector-triggered processing body formation attenuates host translation via ER stress responses and autophagy upon bacterial infection” #proteostasis #plantimmunity 🧵(1/16)
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Gert Bange
Wow! The Proteasome generates antimicrobial peptides that directly affect bacterial membranes #proteostasis
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Cell-autonomous innate immunity by proteasome-derived defence peptides - Nature
Proteasomal degradation of cellular proteins generate defence peptides constitutively and in response to bacterial infection. Such peptides might provide a source of natural antibiotics that...
www.nature.com
March 5, 2025 at 7:46 PM
Wow! The Proteasome generates antimicrobial peptides that directly affect bacterial membranes #proteostasis
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Gert Bange
Structure of human PINK1 at a mitochondrial TOM-VDAC array | Science www.science.org/doi/10.1126/...
Structure of human PINK1 at a mitochondrial TOM-VDAC array
Mutations in the ubiquitin kinase PINK1 cause early onset Parkinson’s Disease, but how PINK1 is stabilized at depolarized mitochondrial translocase complexes has remained poorly understood. We determi...
www.science.org
March 14, 2025 at 5:34 AM
Structure of human PINK1 at a mitochondrial TOM-VDAC array | Science www.science.org/doi/10.1126/...