Aslan
@aslantasdogan.bsky.social
Assoc. Prof. for Dermatology @UniklinikEssen
,Alumni @SJMorrison_. Physician-Scientist. Emmy Noether Fellow,
@ERC_Research, Focus on Cancer Metabolism/Metastasis
,Alumni @SJMorrison_. Physician-Scientist. Emmy Noether Fellow,
@ERC_Research, Focus on Cancer Metabolism/Metastasis
Reposted by Aslan
1/Patient-derived xenografts (PDXs) are used in preclinical testing of cancer therapies, including metabolic therapies. We determined which metabolic properties are retained, and which are lost, when melanomas from patients are implanted and passaged as PDXs in mice.
www.nature.com/articles/s42...
www.nature.com/articles/s42...
Conservation and divergence of metabolic phenotypes between patient tumours and matched xenografts - Nature Metabolism
Rao and Cai et al. perform a detailed metabolic comparison between primary tumours from patients and their matching xenografts, which identify conserved as well as divergent metabolic patterns.
www.nature.com
July 29, 2025 at 2:56 PM
1/Patient-derived xenografts (PDXs) are used in preclinical testing of cancer therapies, including metabolic therapies. We determined which metabolic properties are retained, and which are lost, when melanomas from patients are implanted and passaged as PDXs in mice.
www.nature.com/articles/s42...
www.nature.com/articles/s42...