Arwen Gao
@arwengao.bsky.social
Assistant Professor&PI | Amsterdam UMC - Location AMC | Aging & Longevity | C. elegans | Lysosome | Metabolism | Genetics | Mother of two boys
Pinned
Arwen Gao
@arwengao.bsky.social
· Jun 26
A lysosomal surveillance response to stress extends healthspan - Nature Cell Biology
Li et al. uncover a lysosomal surveillance response whereby intestinal lumen deacidification induces a transcriptional programme that boosts lysosomal activity and improves protein aggregate clearance...
www.nature.com
Thrilled to share our new study:
“A lysosomal surveillance response to stress extends healthspan”
Knockdown of vha-6 in C. elegans activates LySR—a protective program that boosts lysosomal activity, clears aggregates, and extends lifespan.
www.nature.com/articles/s41...
#lysosomes #LySR #aging
“A lysosomal surveillance response to stress extends healthspan”
Knockdown of vha-6 in C. elegans activates LySR—a protective program that boosts lysosomal activity, clears aggregates, and extends lifespan.
www.nature.com/articles/s41...
#lysosomes #LySR #aging
More than 100 participants, it’s happening NOW! #DuSRA2025
November 10, 2025 at 11:11 AM
More than 100 participants, it’s happening NOW! #DuSRA2025
Check out our newly published paper at IScience! We showed that knocking down a fat-processing enzyme gene, plag-15, can switch on lysosome programs and extend lifespan in worms! cell.com/iscience/ful...
#Healthyaging #lysosome #Celegans
#Healthyaging #lysosome #Celegans
Targeting phospholipase PLAG-15 promotes healthy aging in C. elegans via lysosomal-related genes
Molecular physiology; Lipidomics; Transcriptomics
cell.com
September 8, 2025 at 7:57 PM
Check out our newly published paper at IScience! We showed that knocking down a fat-processing enzyme gene, plag-15, can switch on lysosome programs and extend lifespan in worms! cell.com/iscience/ful...
#Healthyaging #lysosome #Celegans
#Healthyaging #lysosome #Celegans
Registration is now open! As one of the organizers, I am looking forward to meeting all the aging researchers in the Netherlands at our annual meeting!
dusra.nl/annual-meeti...
#DuSRA #AmsterdamUMC #Agingresearch #Netherlands
dusra.nl/annual-meeti...
#DuSRA #AmsterdamUMC #Agingresearch #Netherlands
Annual meeting 2025
Welcome message from the organizing committee
In 2025, the Dutch Society for Aging Research (DuSRA) is proud to host its Annual Scientific Meeting on 10–11 November 2025 in Amsterdam.
Over two days, ...
dusra.nl
August 19, 2025 at 9:08 AM
Registration is now open! As one of the organizers, I am looking forward to meeting all the aging researchers in the Netherlands at our annual meeting!
dusra.nl/annual-meeti...
#DuSRA #AmsterdamUMC #Agingresearch #Netherlands
dusra.nl/annual-meeti...
#DuSRA #AmsterdamUMC #Agingresearch #Netherlands
Reposted by Arwen Gao
Congrats to the Terytty, @arwengao.bsky.social and colleagues for identifying the importance of Lysosomal Surveillance Response (LysR) in fighting age-related protein accumulation. news.epfl.ch/news/a-recyc...
www.nature.com/articles/s41...
www.nature.com/articles/s41...
A recycling mechanism that helps cells fight aging
An international team led by EPFL has discovered a powerful anti-aging pathway in roundworms, revealing how boosting the cell’s lysosomes can help clear waste and promote healthy aging. The findings o...
news.epfl.ch
July 3, 2025 at 2:03 PM
Congrats to the Terytty, @arwengao.bsky.social and colleagues for identifying the importance of Lysosomal Surveillance Response (LysR) in fighting age-related protein accumulation. news.epfl.ch/news/a-recyc...
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Thrilled to share our new study:
“A lysosomal surveillance response to stress extends healthspan”
Knockdown of vha-6 in C. elegans activates LySR—a protective program that boosts lysosomal activity, clears aggregates, and extends lifespan.
www.nature.com/articles/s41...
#lysosomes #LySR #aging
“A lysosomal surveillance response to stress extends healthspan”
Knockdown of vha-6 in C. elegans activates LySR—a protective program that boosts lysosomal activity, clears aggregates, and extends lifespan.
www.nature.com/articles/s41...
#lysosomes #LySR #aging
A lysosomal surveillance response to stress extends healthspan - Nature Cell Biology
Li et al. uncover a lysosomal surveillance response whereby intestinal lumen deacidification induces a transcriptional programme that boosts lysosomal activity and improves protein aggregate clearance...
www.nature.com
June 26, 2025 at 11:02 AM
Thrilled to share our new study:
“A lysosomal surveillance response to stress extends healthspan”
Knockdown of vha-6 in C. elegans activates LySR—a protective program that boosts lysosomal activity, clears aggregates, and extends lifespan.
www.nature.com/articles/s41...
#lysosomes #LySR #aging
“A lysosomal surveillance response to stress extends healthspan”
Knockdown of vha-6 in C. elegans activates LySR—a protective program that boosts lysosomal activity, clears aggregates, and extends lifespan.
www.nature.com/articles/s41...
#lysosomes #LySR #aging
Reposted by Arwen Gao
Save the date! DTMC 2025 is promising to be super exciting! Watch this space for updates, or sign up for the newsletter!
December 3, 2024 at 7:38 PM
Save the date! DTMC 2025 is promising to be super exciting! Watch this space for updates, or sign up for the newsletter!
Team members from our group are presenting at #DTMC2025😊😊
May 28, 2025 at 11:09 AM
Team members from our group are presenting at #DTMC2025😊😊