Anne Vassalli
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annevassalli.bsky.social
Anne Vassalli
@annevassalli.bsky.social
56 followers 88 following 4 posts
Sleep and hypothalamic control of brain states & cell fates | Arousal disorders incl Narcolepsy, ADHD, OCD 🔶@Innosuisse "Proof-of-concept of narcolepsy reversal by epigenetic therapy"
https://wp.unil.ch/vassallilab/
Migrated from https://x.com/AnneVassalli
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annevassalli.bsky.social
Excited to share our new preprint!
www.biorxiv.org/content/10.1...
Divergent modulation of dopaminergic neurons by hypocretin/orexin receptors-1 and -2 shapes dopaminergic cell activity and socio-emotional behavior
Tzanoulinou et al

Supported by @snsf.ch
Summary depiction of divergent neuromodulation of dopaminergic neurons by hypocretin/orexin receptors-1 and -2 as reflected at electrophysiological and behavioral levels
July 25, 2025 at 4:06 PM
Reposted by Anne Vassalli
shukryjhabib.bsky.social
Join us in Lausanne 🇨🇭 for the Lac Léman Regenerative Medicine Symposium, Sept 17–19, 2025! 🔬

Stem cells, aging, bioengineering — shaping the future of regenerative medicine.

habiblab.org/l2rm

🎟️ Students 25 CHF | Postdocs/Faculty 50 CHF | Industry 150 CHF
#L2RM #RegenMed #StemCells
May 4, 2025 at 2:51 PM
annevassalli.bsky.social
Our follow-up study on the orexin↔dopamine neuronal interplay is here to share! We discover opposite action of #hypocretin/orexin A vs B via #OX1R vs #OX2R on VTADA cell excitability +demonstrate striking distinct impact of DA cell Ox1 vs 2R loss on mouse behavior in socioemotional&cognitive domain
Divergent modulation of dopaminergic neurons by hypocretin/orexin receptors-1 and -2 shapes dopaminergic cell activity and socio-emotional behavior
Many neuropsychiatric disorders involve dysregulation of the dopaminergic (DA) input to the forebrain. Of particular relevance are DA projections originating from the midbrain ventral tegmental area (...
www.biorxiv.org
February 18, 2025 at 5:27 AM