Dr. Curmudgeon
@altgovdoc.altgov.info
General health and science information
#medsky #emedsky
Posts 🚫 med advice. Please, seek the care of your physician if you have any concerns.
#medsky #emedsky
Posts 🚫 med advice. Please, seek the care of your physician if you have any concerns.
Pinned
Dr. Curmudgeon
@altgovdoc.altgov.info
· Nov 10
a doctor with a stethoscope on his head and the words what seems to be the trouble below him
Alt: a doctor with a stethoscope on his head and the words what seems to be the trouble below him
media.tenor.com
Hello, curmudgeon doctor is in Allow time for orientation before adopting my list, am searching for relevant medical/science follows Recommendations welcome
I’m here for you.
Rules
Ask questions about articles, zero are stupid
No politics
Be kind
I have Long Covid & dyslexia & will make mistakes
I’m here for you.
Rules
Ask questions about articles, zero are stupid
No politics
Be kind
I have Long Covid & dyslexia & will make mistakes
Reposted by Dr. Curmudgeon
With tomorrow being #NoKingsDay, we have a unique opportunity to piss the other side off, to protect yourself and those around you. Wearing a mask at the marches and events does this. The bonus bonus affect is that it will also help mitigate the fall Covid boom! How the fuck about that?!?!
Devastating changes to vaccine policy will be catastrophic for the fall/winter flu and covid season. Last season 2500 covid deaths per week. There will likely be a significant increase
Mask 😷 up, air quality, isolate when ill, spread the word, take care of each other
www.nejm.org/doi/full/10....
Mask 😷 up, air quality, isolate when ill, spread the word, take care of each other
www.nejm.org/doi/full/10....
An Evidence-Based Approach to Covid-19 Vaccination | NEJM
This article from the FDA compares broad U.S. recommendations on Covid vaccination with those from other countries and announces the adoption of an evidence-based approach to such recommendations.
www.nejm.org
June 13, 2025 at 4:48 PM
With tomorrow being #NoKingsDay, we have a unique opportunity to piss the other side off, to protect yourself and those around you. Wearing a mask at the marches and events does this. The bonus bonus affect is that it will also help mitigate the fall Covid boom! How the fuck about that?!?!
Devastating changes to vaccine policy will be catastrophic for the fall/winter flu and covid season. Last season 2500 covid deaths per week. There will likely be a significant increase
Mask 😷 up, air quality, isolate when ill, spread the word, take care of each other
www.nejm.org/doi/full/10....
Mask 😷 up, air quality, isolate when ill, spread the word, take care of each other
www.nejm.org/doi/full/10....
An Evidence-Based Approach to Covid-19 Vaccination | NEJM
This article from the FDA compares broad U.S. recommendations on Covid vaccination with those from other countries and announces the adoption of an evidence-based approach to such recommendations.
www.nejm.org
June 13, 2025 at 3:46 PM
Devastating changes to vaccine policy will be catastrophic for the fall/winter flu and covid season. Last season 2500 covid deaths per week. There will likely be a significant increase
Mask 😷 up, air quality, isolate when ill, spread the word, take care of each other
www.nejm.org/doi/full/10....
Mask 😷 up, air quality, isolate when ill, spread the word, take care of each other
www.nejm.org/doi/full/10....
Korea has some promising Pan-coronavirus vaccine research pmc.ncbi.nlm.nih.gov/articles/PMC...
Pan‐Variant SARS‐CoV‐2 Vaccines Induce Protective Immunity by Targeting Conserved Epitopes
The development of a globally effective COVID‐19 vaccine faces significant challenges, particularly in redirecting the B‐cell response from immunodominant yet variable regions of viral proteins toward...
pmc.ncbi.nlm.nih.gov
June 12, 2025 at 3:52 PM
Korea has some promising Pan-coronavirus vaccine research pmc.ncbi.nlm.nih.gov/articles/PMC...
This was promising research for a vaccine that would encompass the class of coronaviruses. The NIG grants for vax development are cancelled taggs.hhs.gov/Content/Data...
www.nature.com/articles/s41...
www.nature.com/articles/s41...
A trivalent protein-based pan-Betacoronavirus vaccine elicits cross-neutralizing antibodies against a panel of coronavirus pseudoviruses - npj Vaccines
npj Vaccines - A trivalent protein-based pan-Betacoronavirus vaccine elicits cross-neutralizing antibodies against a panel of coronavirus pseudoviruses
www.nature.com
June 12, 2025 at 3:36 PM
This was promising research for a vaccine that would encompass the class of coronaviruses. The NIG grants for vax development are cancelled taggs.hhs.gov/Content/Data...
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Males and females process pain through different brain pathways. Current pain management has been directed to how males process pain. This might also explain why females suffer more from chronic pain. pmc.ncbi.nlm.nih.gov/articles/PMC...
Self-regulated analgesia in males but not females is mediated by endogenous opioids
Converging lines of preclinical and clinical research indicate that females, in stark contrast to males, display an increased prevalence of chronic pain. Females also demonstrate weaker analgesic effi...
pmc.ncbi.nlm.nih.gov
June 2, 2025 at 2:12 PM
Males and females process pain through different brain pathways. Current pain management has been directed to how males process pain. This might also explain why females suffer more from chronic pain. pmc.ncbi.nlm.nih.gov/articles/PMC...
A prospective study in Lancet reveals 2% of those with Long Covid resolve, most have symptoms that continue at 2-3 years affecting their quality of life and mental health. “Long COVID-associated differences across multiple physical health outcomes, including overall
1/3
1/3
March 21, 2025 at 1:45 PM
A prospective study in Lancet reveals 2% of those with Long Covid resolve, most have symptoms that continue at 2-3 years affecting their quality of life and mental health. “Long COVID-associated differences across multiple physical health outcomes, including overall
1/3
1/3
Please, forgive my absence of late. PASC/Long Covid can really take over your life. Even missing the day set aside to recognize this very illness that has affected 1/20 Americans. Will be interested in bringing you updates concerning this as well as some of the other latest health issues of note.
March 17, 2025 at 3:09 AM
Please, forgive my absence of late. PASC/Long Covid can really take over your life. Even missing the day set aside to recognize this very illness that has affected 1/20 Americans. Will be interested in bringing you updates concerning this as well as some of the other latest health issues of note.
Stanford has developed new antibody therapy for Covid effective against the non-mutating portions of the virus
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Bispecific antibodies targeting the N-terminal and receptor binding domains potently neutralize SARS-CoV-2 variants of concern
Bispecific antibodies incorporating a cross-reactive NTD-specific antibody are resilient to SARS-CoV-2 variants of concern.
www.science.org
March 10, 2025 at 2:20 AM
Stanford has developed new antibody therapy for Covid effective against the non-mutating portions of the virus
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Dr. Curmudgeon
Thank you Doc.
There are many "alt" accounts who haven't requested to join, have dropped out of vetting, some outright ghosted, and some who didn't make the cut.
Stick with the starter pack. They're added immediately after vetting & have agreed to the standards for which #AltGov is known.
There are many "alt" accounts who haven't requested to join, have dropped out of vetting, some outright ghosted, and some who didn't make the cut.
Stick with the starter pack. They're added immediately after vetting & have agreed to the standards for which #AltGov is known.
March 1, 2025 at 10:02 PM
Thank you Doc.
There are many "alt" accounts who haven't requested to join, have dropped out of vetting, some outright ghosted, and some who didn't make the cut.
Stick with the starter pack. They're added immediately after vetting & have agreed to the standards for which #AltGov is known.
There are many "alt" accounts who haven't requested to join, have dropped out of vetting, some outright ghosted, and some who didn't make the cut.
Stick with the starter pack. They're added immediately after vetting & have agreed to the standards for which #AltGov is known.
Some new folks have cleared the #AltGov verification and vetting process. See the official list at @altspaceforce.altgov.info
In your enthusiasm for democracy, please also remember caution in these times. Disinformation has been and will be the greatest weapon.
In your enthusiasm for democracy, please also remember caution in these times. Disinformation has been and will be the greatest weapon.
March 1, 2025 at 9:47 PM
Some new folks have cleared the #AltGov verification and vetting process. See the official list at @altspaceforce.altgov.info
In your enthusiasm for democracy, please also remember caution in these times. Disinformation has been and will be the greatest weapon.
In your enthusiasm for democracy, please also remember caution in these times. Disinformation has been and will be the greatest weapon.
“What we know about the illnesses that have sickened over 400 people and killed more than 50 in Congo” medicalxpress.com/news/2025-02...
What we know about the illnesses that have sickened over 400 people and killed more than 50 in Congo
Unidentified illnesses in northwestern Congo have killed more than 50 people over the past five weeks, nearly half of them within hours after they felt sick.
medicalxpress.com
February 28, 2025 at 2:54 AM
“What we know about the illnesses that have sickened over 400 people and killed more than 50 in Congo” medicalxpress.com/news/2025-02...
Predictors for sever Covid infections->age, chronic kidney disease, chronic obstructive pulmonary disease, Alzheimer's disease, heart failure, anaemia, and glucocorticoid use.
www.thelancet.com/journals/ecl...
www.thelancet.com/journals/ecl...
Leveraging near-real-time patient and population data to incorporate fluctuating risk of severe COVID-19: development and prospective validation of a personalised risk prediction tool
Our novel risk prediction tool uses a simple method to adjust for temporal changes
and can be implemented to facilitate uptake of evidence-based therapies. The study
provides proof-of-concept for leve...
www.thelancet.com
February 23, 2025 at 7:22 PM
Predictors for sever Covid infections->age, chronic kidney disease, chronic obstructive pulmonary disease, Alzheimer's disease, heart failure, anaemia, and glucocorticoid use.
www.thelancet.com/journals/ecl...
www.thelancet.com/journals/ecl...
Long Covid effects on the brain have been numerous to include many new psychiatric symptoms.
Anxiety, depression and even psychosis in patients without any previous underlying conditions or worsened when they do. www.thelancet.com/journals/ecl...
Anxiety, depression and even psychosis in patients without any previous underlying conditions or worsened when they do. www.thelancet.com/journals/ecl...
First-Episode Psychosis incidence pre-, during, and post-COVID-19 pandemic: a six-year natural quasi-experimental study in South London
FEP incidence in South London increased during the peak of the COVID-19 pandemic,
particularly among Black and Asian individuals.
www.thelancet.com
February 23, 2025 at 7:15 PM
Long Covid effects on the brain have been numerous to include many new psychiatric symptoms.
Anxiety, depression and even psychosis in patients without any previous underlying conditions or worsened when they do. www.thelancet.com/journals/ecl...
Anxiety, depression and even psychosis in patients without any previous underlying conditions or worsened when they do. www.thelancet.com/journals/ecl...
A thread about those who shy away from vaccinations 🧵
Having had long conversations with many of these, the predominant characteristic of their decision making is fear. Consumption of propaganda and lack of trusted sources for information. In the choice between data and fear, the more powerful motivator wins, fear wins. It takes
February 9, 2025 at 10:31 PM
A thread about those who shy away from vaccinations 🧵
Continued ability to develop this H5N1 avian flu vaccine would be an important step. This would of course require continued funding of the science.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Development of a nucleoside-modified mRNA vaccine against clade 2.3.4.4b H5 highly pathogenic avian influenza virus - Nature Communications
Highly pathogenic avian influenza viruses from H5 clade 2.3.4.4b are circulating widely in birds and have recently caused large outbreaks in mammals. Here, Furey et al. develop a clade 2.3.4.4b HA-exp...
www.nature.com
February 9, 2025 at 4:24 PM
Continued ability to develop this H5N1 avian flu vaccine would be an important step. This would of course require continued funding of the science.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Measles outbreak expands in West Texas around county with low vaccination rate | CNN
Record numbers of children are not being vaccinated. You must have 95% to prevent epidemics.
www.cdc.gov/schoolvaxvie...
This is in addition
Record numbers of children are not being vaccinated. You must have 95% to prevent epidemics.
www.cdc.gov/schoolvaxvie...
This is in addition
Vaccination Coverage and Exemptions among Kindergartners
View national and state-level school vaccination coverage and exemption estimates.
www.cdc.gov
February 8, 2025 at 2:18 PM
Measles outbreak expands in West Texas around county with low vaccination rate | CNN
Record numbers of children are not being vaccinated. You must have 95% to prevent epidemics.
www.cdc.gov/schoolvaxvie...
This is in addition
Record numbers of children are not being vaccinated. You must have 95% to prevent epidemics.
www.cdc.gov/schoolvaxvie...
This is in addition
Notes from the Field: Long COVID and Significant Long COVID–Associated Activity Limitation Among Adults, by Jurisdiction — United States, 2023 | MMWR
February 5, 2025 at 4:35 PM
Notes from the Field: Long COVID and Significant Long COVID–Associated Activity Limitation Among Adults, by Jurisdiction — United States, 2023 | MMWR
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a disabling chronic illness. Most often contracted after an infection. Present in 85% of those with Long Covid (LC) that affects 7.5% of the population, costing $7 trillion in lost wages. Patients experience 1/4
February 5, 2025 at 4:30 PM
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a disabling chronic illness. Most often contracted after an infection. Present in 85% of those with Long Covid (LC) that affects 7.5% of the population, costing $7 trillion in lost wages. Patients experience 1/4
In this study they looked at how they used oxygen and used a chemical marker type MRI to look at the hearts of people who had mild Covid ≈3 yrs prior. These ppl had normal hearts before Covid and normal hearts at rest. When they exercised about 1/3 showed signs of damage from
February 4, 2025 at 3:47 PM
In this study they looked at how they used oxygen and used a chemical marker type MRI to look at the hearts of people who had mild Covid ≈3 yrs prior. These ppl had normal hearts before Covid and normal hearts at rest. When they exercised about 1/3 showed signs of damage from
When patients get into trouble with their congestive heart failure the would come see me. This is what I sent them home with for years. Because it works!
Do you know your dry weight? Have a discussion with your physician & plan. Keeping you healthy & out of the ER saves you & your expenses.
Do you know your dry weight? Have a discussion with your physician & plan. Keeping you healthy & out of the ER saves you & your expenses.
Patient self-directed sliding scale furosemide is an underutilized tool in CHF management
Can a simple weight-based dosing strategy empower patients to manage CHF, prevent exacerbations, and reduce ED visits? Let's dive in! 👇 #medsky #pharmsky #cardiosky #EMsky #GPsky #MedEd 1/
Can a simple weight-based dosing strategy empower patients to manage CHF, prevent exacerbations, and reduce ED visits? Let's dive in! 👇 #medsky #pharmsky #cardiosky #EMsky #GPsky #MedEd 1/
a person is measuring their weight on a scale that goes up to 40
ALT: a person is measuring their weight on a scale that goes up to 40
media.tenor.com
February 4, 2025 at 4:06 AM
When patients get into trouble with their congestive heart failure the would come see me. This is what I sent them home with for years. Because it works!
Do you know your dry weight? Have a discussion with your physician & plan. Keeping you healthy & out of the ER saves you & your expenses.
Do you know your dry weight? Have a discussion with your physician & plan. Keeping you healthy & out of the ER saves you & your expenses.
You can print up the chart and discuss strategies with your physician. The more you know, the better you are able to participate in your care.
Strategies to Help Patients Afford Their Medicines in the US | Clinical Pharmacy and Pharmacology | JAMA | JAMA Network
Strategies to Help Patients Afford Their Medicines in the US | Clinical Pharmacy and Pharmacology | JAMA | JAMA Network
February 3, 2025 at 3:06 AM
You can print up the chart and discuss strategies with your physician. The more you know, the better you are able to participate in your care.
Strategies to Help Patients Afford Their Medicines in the US | Clinical Pharmacy and Pharmacology | JAMA | JAMA Network
Strategies to Help Patients Afford Their Medicines in the US | Clinical Pharmacy and Pharmacology | JAMA | JAMA Network
A Practical Approach to Reducing Patients' Prescription Costs www.aafp.org/pubs/fpm/iss...
A Practical Approach to Reducing Patients' Prescription Costs
A single screening question and an arsenal of cost-reducing strategies can help you help your patients afford their medications.
www.aafp.org
February 3, 2025 at 3:02 AM
A Practical Approach to Reducing Patients' Prescription Costs www.aafp.org/pubs/fpm/iss...
Good information to have as the patient as well.
Strategies to Help Patients Navigate High Prescription Drug Costs | Health Care Economics, Insurance, Payment | JAMA | JAMA Network
Strategies to Help Patients Navigate High Prescription Drug Costs | Health Care Economics, Insurance, Payment | JAMA | JAMA Network
February 3, 2025 at 2:59 AM
Good information to have as the patient as well.
Strategies to Help Patients Navigate High Prescription Drug Costs | Health Care Economics, Insurance, Payment | JAMA | JAMA Network
Strategies to Help Patients Navigate High Prescription Drug Costs | Health Care Economics, Insurance, Payment | JAMA | JAMA Network