Alex Wiesman
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alexwiesman.bsky.social
Alex Wiesman
@alexwiesman.bsky.social
Scientist studying neural dynamics in Parkinson's disease at SFU.

Tryhard home cook | sci-fi nerd | movie buff. Views my own.
Pinned
Now published OA in Movement Disorders: doi.org/10.1002/mds....

We find that MEG can be used to quantify the "off-target" effects of dopamine therapies in people living with #Parkinson's disease

#neuroskyence

🧵👇

(1/9)
Cortical Effects of Dopamine Replacement Account for Clinical Response Variability in Parkinson's Disease
Background Individual variability in clinical response to dopamine replacement therapy (DRT) is a key barrier to efficacious treatment for patients with Parkinson's disease (PD). A better understand...
doi.org
Reposted by Alex Wiesman
Exciting news from the chairs of Biomag 2026, Prof. Jiahong Gao and Prof. Huan Luo — the conference website is now live: biomag2026.scimeeting.cn The meetings take place in Beijing, 23–25 August 2026. Save the date and start thinking about ideas for posters and symposia! Please share with colleagues
BIOMAG 2025,在线会议,会议直播平台,网络会议直播,美迪康会务通,学术会议管理系统,会议活动管理,注册签到管理,会场幻灯片传输转播,PPT传输,会议网络直播,电子壁报管理系统,医学会,会员管理系统
biomag2026.scimeeting.cn
November 11, 2025 at 5:28 PM
Reposted by Alex Wiesman
🚨🧠🚨 POSTDOC POSITION 🚨🧠🚨 in my lab: www.ru.nl/en/working-a... Connectivity in Working Memory. Deadline 12 Nov! Apply via website; please repost.
Postdoc Position: Neural Circuitry Underlying Working Memory | Radboud University
Do you want to work as a Postdoc Position: Neural Circuitry Underlying Working Memory at the Faculty of Social Sciences? Check our vacancy!
www.ru.nl
November 9, 2025 at 9:17 AM
Reposted by Alex Wiesman
We just published a paper in PNAS, showing microstructural changes to the hippocampus in aging and presymptomatic Alzheimer's disease - in humans, in vivo.

We continue to show the value of structural MRI beyond simply measuring large-scale atrophy!

Read here: ow.ly/1NvV50XkXnX
November 9, 2025 at 5:00 PM
Reposted by Alex Wiesman
🚨 Brain Age vs Direct Models in Alzheimer’s disease (AD) 🚨 A thread 🧵

1/ Brain age is a powerful indicator of general brain health, trained on massive datasets. But does this translate to better prediction for specific outcomes, like AD?

Preprint by @twktan.bsky.social : doi.org/10.1101/2024...
November 20, 2024 at 3:06 AM
Reposted by Alex Wiesman
New paper out in npj Digital Medicine! Fayed Rassoulou demonstrates how electrophysiology + machine learning can help identify the optimal contact for deep brain stimulation. rdcu.be/eNgG1
Electrophysiological signatures predict the therapeutic window of deep brain stimulation electrode contacts
npj Digital Medicine - Electrophysiological signatures predict the therapeutic window of deep brain stimulation electrode contacts
rdcu.be
October 30, 2025 at 4:11 PM
Reposted by Alex Wiesman
Stoked to see our study out in final form! Big kudos to @jonathanamichaels.bsky.social for driving this along for the past 5 years.
October 29, 2025 at 4:47 PM
Reposted by Alex Wiesman
Don't miss next week's seminar! We will host Jason Chan for a talk titled "From cognition to action in Parkinson’s disease and movement disorders." Please note that the in-person location of the seminar has changed to ASB 10908. For more info, visit: rebrand.ly/e4hu4yn
We are excited to announce our upcoming seminar series! Join us on October 30th, at 2:30 pm PDT, for a talk from @jlchan.bsky.social, titled "From cognition to action in Parkinson’s disease and movement disorders." For more information, visit: rebrand.ly/e4hu4yn
October 27, 2025 at 3:00 PM
Reposted by Alex Wiesman
Next week, we launch our first Research Training Workshop! Join us to learn about PCA, ICA, and SVD. All are welcome to attend. For more information, visit: rebrand.ly/z9umlrp
We are excited to announce the launch of our Research Training Workshop series! Our first workshop will be an introduction to dimensionality reduction, including PCA, ICA and SVD. All are welcome. To learn more, visit: rebrand.ly/ee5864b
October 23, 2025 at 3:03 PM
Reposted by Alex Wiesman
Tune in next week as we host Jason Chan for a talk titled "From cognition to action in Parkinson’s disease and movement disorders." For more info, visit: rebrand.ly/e4hu4yn
We are excited to announce our upcoming seminar series! Join us on October 30th, at 2:30 pm PDT, for a talk from @jlchan.bsky.social, titled "From cognition to action in Parkinson’s disease and movement disorders." For more information, visit: rebrand.ly/e4hu4yn
October 22, 2025 at 3:02 PM
Reposted by Alex Wiesman
#CNS2026 Satellite - International Sleep Replay Workshop, Friday, March 6, 2026, 8:00 am - 6:00 pm, Grand Ballroom

CNS 2026 will be preceded by a one-day satellite event focusing on sleep and memory - the 5th International Sleep Replay Workshop. Learn more: isrw.bio.uci.edu

@cnsnews.bsky.social
October 14, 2025 at 7:32 PM
Reposted by Alex Wiesman
𝗘𝗻𝗱 𝗼𝗳 𝘁𝗵𝗲 𝗲𝗺𝗽𝗶𝗿𝗲 𝗼𝗳 𝗻𝗲𝘂𝗿𝗼𝗻𝘀 𝗶𝗻 𝘁𝗵𝗲 𝗯𝗿𝗮𝗶𝗻??
Astrocytes in the regulation of fear memories!
www.nature.com/articles/s41...
#neuroskyence
h/t @claeneuro.bsky.social
The astrocytic ensemble acts as a multiday trace to stabilize memory - Nature
Emotional experience evokes signalling in astrocytes, which form an ensemble that is reinforced by secondary astrocytic state changes resulting from repeated experience, leading to memory stabilizatio...
www.nature.com
October 21, 2025 at 5:57 PM
Reposted by Alex Wiesman
📢 To Prospective Ph.D. students: I am planning to accept a #PhD graduate student for Fall 2026 through the Brown #Neuroscience Department. Learn more about our research and how to apply on our lab website! 🧠👇👇👇

sites.brown.edu/oh-ctnlab/av...
Available Positions
Full-time Research Assistant/Lab Manager [OPEN] A highly motivated, recent college graduate is sought to join our lab and play a vital role as Research Assistant/Lab Manager in studying visual memory,...
sites.brown.edu
October 17, 2025 at 2:08 PM
Reposted by Alex Wiesman
Excited to share our latest work is up on bioRxiv! Looking at capillary flow speed changes we show that psilocybin prolongs the neurovascular coupling response to a visual stimulus. 🍄🔬🧠🩸

@chris-schaffer.bsky.social @alexkwan.bsky.social @sn-lab.bsky.social

Preprint:
www.biorxiv.org/content/10.1...
August 1, 2025 at 5:06 PM
Reposted by Alex Wiesman
SFU is Canada’s top comprehensive university! 🍁

Continuing a tradition of excellence, Maclean's has ranked SFU in the top spot for 17 of the last 18 years, describing it as a "contemporary, inventive, and forward thinking" institution.

Learn more at the link below.
SFU tops national rankings again as Canada’s leading comprehensive university
www.sfu.ca
October 15, 2025 at 9:04 PM
Reposted by Alex Wiesman
Check out our latest paper, a collaboration with @tobiasuhauser.bsky.social using gamified computational psychiatry measures to explore brain-behavioral correlates of decision making!
1/ To explore or to exploit? I’m excited to share my new preprint with @tobiasuhauser.bsky.social and @micahgallen.com, correlating variations in cortical microstructures with individual differences in exploration-exploitation behaviours, using a gamified task! 🧵 www.biorxiv.org/content/10.1...
October 15, 2025 at 12:10 PM
Reposted by Alex Wiesman
🧪🧠 My lab is seeking Experimental Psychology (Psych Science) graduate trainees for Fall 2026.

Please consider applying

www.torontomu.ca/psychology/p...

Deadline for applications is December 1, 2025

#neurosky #phd
How to Apply
www.torontomu.ca
October 15, 2025 at 2:33 PM
Reposted by Alex Wiesman
We are excited to announce the launch of our Research Training Workshop series! Our first workshop will be an introduction to dimensionality reduction, including PCA, ICA and SVD. All are welcome. To learn more, visit: rebrand.ly/ee5864b
October 15, 2025 at 3:00 PM
Reposted by Alex Wiesman
Exciting news for SFU and BC students.
www.sfu.ca/sfunews/stor...
SFU School of Medicine opens applications, announces plans for new Surrey location
www.sfu.ca
October 14, 2025 at 7:49 PM
Reposted by Alex Wiesman
So great to see this moving forward.
October 15, 2025 at 2:03 AM
Incredibly grateful for this support from the Canada Foundation for Innovation

With the new infrastructure, our Neurophysiology of Aging and Neurodegeneration Lab at @sfu.ca has already begun to develop exciting research - stay tuned! 🧠 👀
Eight SFU researchers have received over $1.4M through the John R. Evans Leadership Fund from the Canada Foundation for Innovation. From advancing clean energy and trustworthy AI to Indigenous sovereignty and more, these projects are driving research that benefits communities across Canada.
Eight outstanding SFU researchers awarded over $1.4 million from John R. Evans Leadership Fund
www.sfu.ca
October 11, 2025 at 12:03 AM
Reposted by Alex Wiesman
🚨 New paper in Nature Methods:
HippoMaps: multiscale cartography of the human hippocampus

Open-source tools & data to explore structure and function of the 🍤🧠 (histology, in/ex vivo MRI, iEEG)

Led by @jordandekraker.bsky.social

docs: hippomaps.readthedocs.io
paper: doi.org/10.1038/s415...
October 2, 2025 at 11:50 AM
Reposted by Alex Wiesman
This is a major milestone for @sylviavilleneuve.bsky.social & PREVENT-AD. Their vision & dedication have led to a series of impactful studies & high-profile publications, and the future promises insights as this unique dataset continues to grow.

alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
The PREVENT‐AD cohort: Accelerating Alzheimer's disease research and treatment in Canada and beyond
The PResymptomatic EValuation of Experimental or Novel Treatments for Alzheimer's Disease (PREVENT-AD) is an investigator-driven study that was created in 2011 and enrolled cognitively normal older ...
alz-journals.onlinelibrary.wiley.com
September 29, 2025 at 5:24 PM
Reposted by Alex Wiesman
A fascinating update about how deep and fast MEG noninvasive imaging can be: differentiation b/w thalamus subnuclei, slow vs fast sleep spindles, and the talent and skills of Emily Coffey & her team. Grateful for being aboard this collaborative work.

doi.org/10.1002/hbm....
Exploring Deep Magnetoencephalography via Thalamo‐Cortical Sleep Spindles
Results from functional connectivity analyses of MEG data (left) show that many thalamic nuclei can be distinguished via functional connectivity (right). However, results depend on the metric and con...
doi.org
September 26, 2025 at 7:01 PM
Reposted by Alex Wiesman
A lot of money & effort goes into building large cohorts that then shape analysis and models that are used for treatment planning - let’s try our best to be inclusive in their creation! End/
September 27, 2025 at 4:27 PM