Alex Fellows
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alexfellows1.bsky.social
Alex Fellows
@alexfellows1.bsky.social
Post-doc in the Carter lab MRC-LMB,
Schiavo lab alumni,
#Axonaltransport
#Neurons 🧠
#Singlemolecule 🔬
Pinned
I meant to do this last week but hi everyone, I'm Alex. I love all things neuronal and spend most of my time trying to image motor proteins and organelle movement in the axon.
Reposted by Alex Fellows
November 5, 2025 at 9:18 AM
Reposted by Alex Fellows
The latest from our group (@lapassmore.bsky.social)! Congrats to James and the rest of the authors!

Phosphorylation-dependent tuning of mRNA deadenylation rates

www.nature.com/articles/s41...
Phosphorylation-dependent tuning of mRNA deadenylation rates - Nature Structural & Molecular Biology
Stowell et al. show that the intrinsically disordered region (IDR) of Puf3 binds the Ccr4–Not deadenylase complex using an extended interface. Phosphorylation of the IDR regulates the interaction to t...
www.nature.com
November 3, 2025 at 12:45 PM
Reposted by Alex Fellows
Get out your calendars! The motors are out of quarantine and we plan to assemble in person on 8th May 2026 at University of Warwick Campus for a fun day on motors and the filaments they walk along. Livestream is planned too. More details on registration, travel bursaries etc. will be revealed soon.
October 30, 2025 at 2:18 PM
Reposted by Alex Fellows
Excited to share a new chapter of my scientific journey in Chris Russo's group — developing a way to freeze proteins faster than they diffuse, paving the way for cryo-EM without air–water interface damage.
Chris Russo and Anastasiia Gusach have developed a new method to prepare #cryoEM samples that avoids protein damage during freezing

Read more: www2.mrc-lmb.cam.ac.uk/a-new-method...

#LMBResearch
October 22, 2025 at 9:33 PM
Reposted by Alex Fellows
🚨 We’re hiring a postdoc! 🚨
Interested in lysosomes, Parkinson’s disease, cell biology, microscopy — or all of the above? Come work with us at the Bonet-Ponce Lab!
Reach out directly: luis.bonetponce@osumc.edu
Learn more: bonetponcelab.com
Let’s chat!
October 14, 2025 at 5:00 PM
Reposted by Alex Fellows
Register for the Dynamic Cell VI conference, Reading, UK, April 2026! This conference focusses on all aspects of cell dynamics, co-organised by @bscb-official.bsky.social and @biochemsoc.bsky.social with @royalmicrosoc.bsky.social and the Chinese Society for Cell Biology.
bit.ly/Dynamic-Cell-VI
October 10, 2025 at 2:24 PM
Reposted by Alex Fellows
Do you know an outstanding cell biologist? Nominations are open for our 2026 medals:

🔬Hooke Medal for outstanding contribution in cell biology
👩‍🔬Women in Cell Biology medal
🧫 Postdoctoral Researcher medal
🔬Raff PhD medal award

Deadline 1st November
September 22, 2025 at 1:21 PM
Reposted by Alex Fellows
Great review of the super #NeuroBioUK2025 meeting in September. Well done to everyone who organised it @exdrososcientia.bsky.social @alexfellows1.bsky.social and @dozenoaks.bsky.social for putting together such a great meeting for the community! 👏🧠🔬 tinyurl.com/4jn7yrmt roll on next year!
NeuroBio UK 2025: Insights, Innovation, and Inspiration in Neuroscience - FocalPlane
NeuroBio UK 2025: Insights, Innovation, and Inspiration in Neuroscience -
tinyurl.com
October 6, 2025 at 7:32 PM
Reposted by Alex Fellows
Happy to share the inaugural paper from the lab. We describe a molecular mechanism for the activation of outer dynein arm motors that power the vital motion of cilia.

Open access link below:
www.nature.com/articles/s41...

Here's a cool animated summary
September 29, 2025 at 7:09 PM
Reposted by Alex Fellows
Wonderful to see our paper on the #organelle signatures of #neurons and #astrocytes out in final form - congratulations, Shannon Rhoads and team!🎉 t.co/BPxKlbU6Ou
September 17, 2025 at 5:38 PM
Reposted by Alex Fellows
Poster boards are ready and waiting for #NeuroBioUK - let’s get this science party started 🥳
September 12, 2025 at 7:37 AM
In York for #NeuroBioUk25! As you can tell from my face..I'm excited!
September 11, 2025 at 4:58 PM
Reposted by Alex Fellows
🚨WiNUK Day 2026 is coming to Birmingham this April!🚨
This year’s theme is neurodiversity🧠🌈
🗓️ Happening during #AutismAwarenessMonth
🗣️ Open call for talks, posters & panels (all genders welcome!)
📅 Deadline: Sun 14 Sept
#WiNUKDay2026 #Neurodiversity #WomenInSTEM
September 8, 2025 at 12:16 PM
Reposted by Alex Fellows
September 9, 2025 at 10:01 AM
Reposted by Alex Fellows
Our new collection offers cell biologists practical, expert-driven guidance and best practices in the design, execution, and analysis of experiments, and the subsequent communication of their results to their peers. 👉 rupress.org/jcb/collecti...

#Reproducibility
September 3, 2025 at 2:15 PM
Reposted by Alex Fellows
The programme is up for #NeuroBioUK25 - take a look! And don’t forget to register by the 3rd of September…. neurobiouk.sites.sheffield.ac.uk/programme
NeuroBioUK - Programme
9 AM Arrival, registration & coffee Session 1: Organelle and synaptic signalling Session Chair: 9:45 AM Introduction 9:50 AM Sally Horton, The Francis Crick Institute, "CDKL5 in synaptic formation,...
neurobiouk.sites.sheffield.ac.uk
August 28, 2025 at 9:11 AM
Do you love the brain? So do we!

Poster and registration deadline is the 3rd September for NeurobioUK 2025. We have an awesome line up of speakers this year. Come and join us in York!

neurobiouk.sites.sheffield.ac.uk/registration
August 18, 2025 at 11:51 AM
Reposted by Alex Fellows
It's an honour to become a Professor at such a wonderful institution @uclqsion.bsky.social @uclbrainscience.bsky.social. The @uclqsneuromuscular.bsky.social is an amazing place to work and I couldn't have done it without my fantastic team, mentors and collaborators:

www.ucl.ac.uk/brain-scienc...
Senior Academic and Early Career Promotions 2024-25
Huge congratulations to the UCL Queen Square Institute of Neurology staff who have been awarded a promotion in this year's promotions round.
www.ucl.ac.uk
August 12, 2025 at 9:22 PM
Reposted by Alex Fellows
Excited to share our latest work with @simonbullock11.bsky.social! We looked at how diverse mRNAs get selected for subcellular localization and it turns out that a single protein can recognize different RNA elements using shared features that weren’t apparent before.
www.biorxiv.org/content/10.1...
August 5, 2025 at 10:43 AM
Reposted by Alex Fellows
Our latest work, in collaboration with the terrific @kashishsingh.bsky.social in the Carter lab @mrclmb.bsky.social is out. So proud of this study and everyone involved...
Cryo-EM structures of Egl-BicD-RNA complexes reveal how diverse mRNAs are selected for subcellular localization https://www.biorxiv.org/content/10.1101/2025.08.02.668268v1
August 5, 2025 at 8:13 AM
Reposted by Alex Fellows
Great talk by @sami-c.bsky.social about the proper use and caveats of AlphaFold2/3 predictions, highly recommended to watch www.youtube.com/watch?v=z7vy...
Structure Prediction and Design using AlphaFold – Sami Chaaban
YouTube video by MRC Laboratory of Molecular Biology
www.youtube.com
August 1, 2025 at 9:53 AM
Reposted by Alex Fellows
Full lineup now announced for the 2026 #JCSimaging! Everything from #cryo #CLEM #superresolution #ExM #tissueimaging and more! Save the date and spread the word!
After the success of our 2023 Imaging Cell Dynamics conference, we’ll be hosting a second #JCSImaging meeting in 2026, organised by @franbottanelli.bsky.social, @guijacquemet.bsky.social‬, @drmichaelway.bsky.social‬ & Giulia Zanetti.
To register your interest: www.biologists.com/meetings/jcs...
July 9, 2025 at 7:00 AM
Reposted by Alex Fellows
Really, really amazing conference. We went last year and the scientific programme and atmosphere were incredible! I 100% recommend attending + submitting an abstract for a talk - spread the word! 🧠
Registration is now open for NeuroBioUK 2025!
This year we're looking forward to hearing from our plenary speaker @cathyabbott.bsky.social. As ever, all other talks chosen from submitted abstracts so get submitting - we can't wait to see you there!

neurobiouk.sites.sheffield.ac.uk/registration
July 8, 2025 at 9:17 AM
Neurobiologists 🧠!! If you want to give a talk at NeurobioUK this year, the deadline is the 1st August. Don't miss your chance to be part of an absolutely awesome meeting.
Registration is now open for NeuroBioUK 2025!
This year we're looking forward to hearing from our plenary speaker @cathyabbott.bsky.social. As ever, all other talks chosen from submitted abstracts so get submitting - we can't wait to see you there!

neurobiouk.sites.sheffield.ac.uk/registration
July 8, 2025 at 9:14 AM
Reposted by Alex Fellows
Registration is now open for NeuroBioUK 2025!
This year we're looking forward to hearing from our plenary speaker @cathyabbott.bsky.social. As ever, all other talks chosen from submitted abstracts so get submitting - we can't wait to see you there!

neurobiouk.sites.sheffield.ac.uk/registration
June 6, 2025 at 3:17 PM