Anna Lehmann
@aelehmann.bsky.social
PhD candidate in the Heitman lab @dukemedschool studying genetics of antimicrobial resistance in fungal pathogens | @dartmouthartsci alum | runner, skier, outdoor enthusiast
Excited to share our new preprint in collaboration with @kellerlab.bsky.social! We identified unstable aneuploidy in Aspergillus fumigatus and explore how aneuploidy-mediated transcriptional and metabolic changes influence antifungal resistance.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Whole-chromosome duplications drive antimicrobial resistance in Aspergillus fumigatus
Aneuploidy causes genome plasticity and enables adaptive responses that confer drug resistance in eukaryotes ranging from fungal pathogens to human cancer cells. Aspergillus fumigatus is a soil-reside...
www.biorxiv.org
October 4, 2025 at 9:53 PM
Excited to share our new preprint in collaboration with @kellerlab.bsky.social! We identified unstable aneuploidy in Aspergillus fumigatus and explore how aneuploidy-mediated transcriptional and metabolic changes influence antifungal resistance.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Anna Lehmann
Extremely excited to present our latest preprint in which we mapped a thermoregulation network that governs virulence in a human fungal pathogen through genetic suppressors, TurboID proximity ligation assay, and functional regulation via domain-truncation alleles.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
August 20, 2025 at 3:00 AM
Extremely excited to present our latest preprint in which we mapped a thermoregulation network that governs virulence in a human fungal pathogen through genetic suppressors, TurboID proximity ligation assay, and functional regulation via domain-truncation alleles.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Anna Lehmann
Thrilled to share that the final chapter of my PhD with @rokaslab.bsky.social is now out in @natcomms.nature.com 🎉
Read it to find out how population structure impacts pathogenicity in Aspergillus flavus, a fungus that infects humans 🧪
rdcu.be/eAToj
Read it to find out how population structure impacts pathogenicity in Aspergillus flavus, a fungus that infects humans 🧪
rdcu.be/eAToj
Population structure in a fungal human pathogen is potentially linked to pathogenicity
Nature Communications - Genetic diversity between clinical and environmental fungal isolates of Aspergillus flavus is poorly studied. Here, the authors analysed genomic data from a global set of...
rdcu.be
August 18, 2025 at 9:48 PM
Thrilled to share that the final chapter of my PhD with @rokaslab.bsky.social is now out in @natcomms.nature.com 🎉
Read it to find out how population structure impacts pathogenicity in Aspergillus flavus, a fungus that infects humans 🧪
rdcu.be/eAToj
Read it to find out how population structure impacts pathogenicity in Aspergillus flavus, a fungus that infects humans 🧪
rdcu.be/eAToj
Reposted by Anna Lehmann
🚨 Fungi + viruses + mammalian lungs? Buckle up! Our new paper in
@natmicrobiol.nature.com
uncovers the story of a deadly fungus and its gnarly viral hitchhiker — and how this duo may change how we diagnose & treat fungal disease 🍄🫁🚨 doi.org/10.1038/s415... ⬇️
@natmicrobiol.nature.com
uncovers the story of a deadly fungus and its gnarly viral hitchhiker — and how this duo may change how we diagnose & treat fungal disease 🍄🫁🚨 doi.org/10.1038/s415... ⬇️
Aspergillus fumigatus dsRNA virus promotes fungal fitness and pathogenicity in the mammalian host - Nature Microbiology
A mycovirus infecting the pathogenic fungus Aspergillus fumigatus enhances its stress tolerance and virulence in mice.
doi.org
August 14, 2025 at 9:46 AM
🚨 Fungi + viruses + mammalian lungs? Buckle up! Our new paper in
@natmicrobiol.nature.com
uncovers the story of a deadly fungus and its gnarly viral hitchhiker — and how this duo may change how we diagnose & treat fungal disease 🍄🫁🚨 doi.org/10.1038/s415... ⬇️
@natmicrobiol.nature.com
uncovers the story of a deadly fungus and its gnarly viral hitchhiker — and how this duo may change how we diagnose & treat fungal disease 🍄🫁🚨 doi.org/10.1038/s415... ⬇️